Population pharmacokinetics of artesunate and dihydroartemisinin during long-term oral administration of artesunate to patients with metastatic breast cancer. (Q44872854)

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scientific article published on 25 September 2014

Language	Label	Description	Also known as
English	Population pharmacokinetics of artesunate and dihydroartemisinin during long-term oral administration of artesunate to patients with metastatic breast cancer.	scientific article published on 25 September 2014

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25248945%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

Population pharmacokinetics of artesunate and dihydroartemisinin during long-term oral administration of artesunate to patients with metastatic breast cancer (English)

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25248945%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

0 references

pharmacokinetics

1 reference

based on heuristic

inferred from title

Cornelia von Hagens

3

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25248945%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

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Therese Ericsson

1

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17 February 2020

Antje Blank

2

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17 February 2020

Michael Ashton

4

1 reference

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17 February 2020

Angela Äbelö

5

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17 February 2020

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25 September 2014

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17 February 2020

European Journal of Clinical Pharmacology

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Europe PubMed Central

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17 February 2020

70

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17 February 2020

12

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17 February 2020

1453-1463

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17 February 2020

Pharmacokinetics of artemisinin-type compounds

1 reference

https://api.crossref.org/works/10.1007%2FS00228-014-1754-2

21 January 2018

Artesunate/mefloquine treatment of multi-drug resistant falciparum malaria

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21 January 2018

Two fixed-dose artemisinin combinations for drug-resistant falciparum and vivax malaria in Papua, Indonesia: an open-label randomised comparison

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https://api.crossref.org/works/10.1007%2FS00228-014-1754-2

21 January 2018

Willmar Schwabe Award 2006: antiplasmodial and antitumor activity of artemisinin--from bench to bedside

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21 January 2018

Anticancer activities of artemisinin and its bioactive derivatives

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https://api.crossref.org/works/10.1007%2FS00228-014-1754-2

21 January 2018

Artesunate activates mitochondrial apoptosis in breast cancer cells via iron-catalyzed lysosomal reactive oxygen species production

1 reference

https://api.crossref.org/works/10.1007%2FS00228-014-1754-2

21 January 2018

Selective toxicity of dihydroartemisinin and holotransferrin toward human breast cancer cells

1 reference

https://api.crossref.org/works/10.1007%2FS00228-014-1754-2

21 January 2018

Review of the clinical pharmacokinetics of artesunate and its active metabolite dihydroartemisinin following intravenous, intramuscular, oral or rectal administration

1 reference

https://api.crossref.org/works/10.1007%2FS00228-014-1754-2

21 January 2018

Glucuronidation of dihydroartemisinin in vivo and by human liver microsomes and expressed UDP-glucuronosyltransferases

1 reference

https://api.crossref.org/works/10.1007%2FS00228-014-1754-2

21 January 2018

Antimalarial bioavailability and disposition of artesunate in acute falciparum malaria

1 reference

https://api.crossref.org/works/10.1007%2FS00228-014-1754-2

21 January 2018

Multiple dose pharmacokinetics of oral artemisinin and comparison of its efficacy with that of oral artesunate in falciparum malaria patients

1 reference

https://api.crossref.org/works/10.1007%2FS00228-014-1754-2

21 January 2018

Artemisinin kinetics and dynamics during oral and rectal treatment of uncomplicated malaria

1 reference

https://api.crossref.org/works/10.1007%2FS00228-014-1754-2

21 January 2018

Multiple dose pharmacokinetics of artemether in Chinese patients with uncomplicated falciparum malaria

1 reference

https://api.crossref.org/works/10.1007%2FS00228-014-1754-2

21 January 2018

Artemisinin autoinduction is caused by involvement of cytochrome P450 2B6 but not 2C9.

1 reference

https://api.crossref.org/works/10.1007%2FS00228-014-1754-2

21 January 2018

Artemisinin and CYP2A6 activity in healthy subjects

1 reference

https://api.crossref.org/works/10.1007%2FS00228-014-1754-2

21 January 2018

A model based assessment of the CYP2B6 and CYP2C19 inductive properties by artemisinin antimalarials: implications for combination regimens.

1 reference

https://api.crossref.org/works/10.1007%2FS00228-014-1754-2

21 January 2018

Perl-speaks-NONMEM (PsN)--a Perl module for NONMEM related programming

1 reference

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21 January 2018

PsN-Toolkit--a collection of computer intensive statistical methods for non-linear mixed effect modeling using NONMEM.

1 reference

https://api.crossref.org/works/10.1007%2FS00228-014-1754-2

21 January 2018

Ways to fit a PK model with some data below the quantification limit

1 reference

https://api.crossref.org/works/10.1007%2FS00228-014-1754-2

21 January 2018

Likelihood based approaches to handling data below the quantification limit using NONMEM VI.

1 reference

https://api.crossref.org/works/10.1007%2FS00228-014-1754-2

21 January 2018

Handling data below the limit of quantification in mixed effect models

1 reference

https://api.crossref.org/works/10.1007%2FS00228-014-1754-2

21 January 2018

Metabolism of antimalarial sesquiterpene lactones.

1 reference

https://api.crossref.org/works/10.1007%2FS00228-014-1754-2

21 January 2018

A semiphysiological pharmacokinetic model for artemisinin in healthy subjects incorporating autoinduction of metabolism and saturable first-pass hepatic extraction

1 reference

https://api.crossref.org/works/10.1007%2FS00228-014-1754-2

21 January 2018

Population pharmacokinetics of artesunate and dihydroartemisinin following single- and multiple-dosing of oral artesunate in healthy subjects

1 reference

https://api.crossref.org/works/10.1007%2FS00228-014-1754-2

21 January 2018

Population pharmacokinetics of artesunate and dihydroartemisinin in pregnant and non-pregnant women with malaria

1 reference

https://api.crossref.org/works/10.1007%2FS00228-014-1754-2

21 January 2018

Multiple peaking phenomena in pharmacokinetic disposition.

1 reference

https://api.crossref.org/works/10.1007%2FS00228-014-1754-2

21 January 2018

Pharmacokinetic parameters of artesunate and dihydroartemisinin in rats infected with Fasciola hepatica.

1 reference

https://api.crossref.org/works/10.1007%2FS00228-014-1754-2

21 January 2018

The distribution pattern of intravenous [(14)C] artesunate in rat tissues by quantitative whole-body autoradiography and tissue dissection techniques

1 reference

https://api.crossref.org/works/10.1007%2FS00228-014-1754-2

21 January 2018

Pharmacokinetics of a five-day oral dihydroartemisinin monotherapy regimen in patients with uncomplicated falciparum malaria

1 reference

https://api.crossref.org/works/10.1007%2FS00228-014-1754-2

21 January 2018

Absence of time-dependent artesunate pharmacokinetics in healthy subjects during 5-day oral administration

1 reference

https://api.crossref.org/works/10.1007%2FS00228-014-1754-2

21 January 2018

Rapid identification of phase I and II metabolites of artemisinin antimalarials using LTQ-Orbitrap hybrid mass spectrometer in combination with online hydrogen/deuterium exchange technique

1 reference

https://api.crossref.org/works/10.1007%2FS00228-014-1754-2

21 January 2018

Artemisinin antimalarials moderately affect cytochrome P450 enzyme activity in healthy subjects

1 reference

https://api.crossref.org/works/10.1007%2FS00228-014-1754-2

21 January 2018

Time course of enzyme induction in humans: effect of pentobarbital on nortriptyline metabolism

1 reference

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21 January 2018

Review: The physiology of saliva and transfer of drugs into saliva

1 reference

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21 January 2018

Use of saliva and capillary blood samples as substitutes for venous blood sampling in pharmacokinetic investigations of artemisinin

1 reference

https://api.crossref.org/works/10.1007%2FS00228-014-1754-2

21 January 2018

Protein binding and alpha : beta anomer ratio of dihydroartemisinin in vivo

1 reference

https://api.crossref.org/works/10.1007%2FS00228-014-1754-2

21 January 2018

Pharmacokinetic principles of drug distribution in saliva

1 reference

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21 January 2018

Estimation of area under the curve for drugs subject to enterohepatic cycling

1 reference

https://pubmed.ncbi.nlm.nih.gov/25248945

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Artemisinin pharmacokinetics is time-dependent during repeated oral administration in healthy male adults

1 reference

https://pubmed.ncbi.nlm.nih.gov/25248945

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Artemisinin-transferrin conjugate retards growth of breast tumors in the rat.

1 reference

https://pubmed.ncbi.nlm.nih.gov/25248945

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adverse effects in patients with acute falciparum malaria treated with artemisinin derivatives

1 reference

https://pubmed.ncbi.nlm.nih.gov/25248945

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Declining concentrations of dihydroartemisinin in plasma during 5-day oral treatment with artesunate for Falciparum malaria.

1 reference

https://pubmed.ncbi.nlm.nih.gov/25248945

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparative pharmacokinetics and effect kinetics of orally administered artesunate in healthy volunteers and patients with uncomplicated falciparum malaria

1 reference

https://pubmed.ncbi.nlm.nih.gov/25248945

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Artemisinin induces omeprazole metabolism in human beings

1 reference

https://pubmed.ncbi.nlm.nih.gov/25248945

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hepatic metabolism of artemisinin drugs—I. Drug metabolism in rat liver microsomes

1 reference

https://pubmed.ncbi.nlm.nih.gov/25248945

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics of artemisinin and artesunate after oral administration in healthy volunteers.

1 reference

https://pubmed.ncbi.nlm.nih.gov/25248945

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Involvement of the mitochondrial pathway and Bim/Bcl-2 balance in dihydroartemisinin-induced apoptosis in human breast cancer in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/25248945

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Estimating population kinetics.

1 reference

https://pubmed.ncbi.nlm.nih.gov/25248945

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Xpose--an S-PLUS based population pharmacokinetic/pharmacodynamic model building aid for NONMEM

1 reference

https://pubmed.ncbi.nlm.nih.gov/25248945

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of artemisinin dimers on rat breast cancer cells in vitro and in vivo.

1 reference

https://pubmed.ncbi.nlm.nih.gov/25248945

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Saliva-plasma drug concentration ratios during absorption: theoretical considerations and pharmacokinetic implications

1 reference

https://pubmed.ncbi.nlm.nih.gov/25248945

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A high-throughput LC-MS/MS assay for quantification of artesunate and its metabolite dihydroartemisinin in human plasma and saliva

1 reference

https://pubmed.ncbi.nlm.nih.gov/25248945

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A pharmacokinetic and pharmacodynamic study of artesunate for vivax malaria.

1 reference

https://pubmed.ncbi.nlm.nih.gov/25248945

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The pharmacokinetics of oral dihydroartemisinin and artesunate in healthy Thai volunteers.

1 reference

https://pubmed.ncbi.nlm.nih.gov/25248945

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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