Review of the clinical pharmacokinetics of artesunate and its active metabolite dihydroartemisinin following intravenous, intramuscular, oral or rectal administration (Q21034080)

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scientific article published on 13 September 2011

Language	Label	Description	Also known as
English	Review of the clinical pharmacokinetics of artesunate and its active metabolite dihydroartemisinin following intravenous, intramuscular, oral or rectal administration	scientific article published on 13 September 2011

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scholarly article

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5 references

22 June 2019

4 November 2019

7 November 2019

28 May 2020

18 July 2021

Review of the clinical pharmacokinetics of artesunate and its active metabolite dihydroartemisinin following intravenous, intramuscular, oral or rectal administration (English)

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infectious disease

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inorganic compound

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4 November 2019

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7 November 2019

pharmacokinetics

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based on heuristic

inferred from title

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18 July 2021

Lawrence Fleckenstein

6

object named as

Lawrence Fleckenstein

author given names

Lawrence

author last names

Fleckenstein

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PubMed publication ID

27 July 2022

author name string

Carrie A Morris

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author given names

Carrie A

author last names

Morris

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PubMed publication ID

27 July 2022

Stephan Duparc

2

author given names

Stephan

author last names

Duparc

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PubMed publication ID

27 July 2022

Isabelle Borghini-Fuhrer

3

author given names

Isabelle

author last names

Borghini-Fuhrer

1 reference

PubMed publication ID

27 July 2022

Donald Jung

4

author given names

Donald

author last names

Jung

1 reference

PubMed publication ID

27 July 2022

Chang-Sik Shin

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author given names

Chang-Sik

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Shin

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PubMed publication ID

27 July 2022

language of work or name

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publication date

13 September 2011

5 references

22 June 2019

4 November 2019

7 November 2019

28 May 2020

18 July 2021

Malaria Journal

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22 June 2019

4 November 2019

7 November 2019

28 May 2020

18 July 2021

10

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1

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263

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copyright license

Creative Commons Attribution 2.0 Generic

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Europe PubMed Central

22 June 2019

Europe PubMed Central

4 November 2019

Europe PubMed Central

7 November 2019

Europe PubMed Central

28 May 2020

Europe PubMed Central

18 July 2021

copyright status

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on focus list of Wikimedia project

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New Fixed-Dose Artesunate-Mefloquine Formulation against Multidrug-Resistant Plasmodium falciparum in Adults: a Comparative Phase IIb Safety and Pharmacokinetic Study with Standard-Dose Nonfixed Artesunate plus Mefloquine

1 reference

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Pharmacokinetics of artesunate after single oral administration to rats

1 reference

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19 March 2017

Artemisinin Resistance in Plasmodium falciparum Malaria

1 reference

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19 March 2017

Population pharmacokinetics of artesunate and dihydroartemisinin following intra-rectal dosing of artesunate in malaria patients

1 reference

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19 March 2017

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1 reference

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19 March 2017

Oral bioavailability of dihydroartemisinin in Vietnamese volunteers and in patients with falciparum malaria

1 reference

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19 March 2017

Population pharmacokinetics of artesunate and dihydroartemisinin in pregnant and non-pregnant women with malaria

1 reference

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12 September 2017

Pharmacokinetics and pharmacodynamics of artesunate and dihydroartemisinin following oral treatment in pregnant women with asymptomatic Plasmodium falciparum infections in Kinshasa DRC.

1 reference

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12 September 2017

Intravenous artesunate for the treatment of severe malaria

1 reference

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12 September 2017

Pharmacokinetics and pharmacodynamics of a new ACT formulation: Artesunate/Amodiaquine (TRIMALACT) following oral administration in African malaria patients.

1 reference

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12 September 2017

Population pharmacokinetics of artesunate and dihydroartemisinin following single- and multiple-dosing of oral artesunate in healthy subjects

1 reference

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12 September 2017

Pharmacokinetics of artemether-lumefantrine and artesunate-amodiaquine in children in Kampala, Uganda

1 reference

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12 September 2017

Population pharmacokinetics of artesunate and amodiaquine in African children

1 reference

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12 September 2017

Pharmacokinetics, tissue distribution and mass balance of radiolabeled dihydroartemisinin in male rats

1 reference

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12 September 2017

Pharmacokinetics and pharmacodynamics of endoperoxide antimalarials

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12 September 2017

Tolerability and pharmacokinetics of non-fixed and fixed combinations of artesunate and amodiaquine in Malaysian healthy normal volunteers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180444

12 September 2017

Major pitfalls in the measurement of artemisinin derivatives in plasma in clinical studies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180444

12 September 2017

Pharmacokinetics and tolerability of artesunate and amodiaquine alone and in combination in healthy volunteers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180444

12 September 2017

Pharmacokinetics of oral artesunate in thai patients with uncomplicated falciparum malaria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180444

12 September 2017

Comparative study of the effectiveness and pharmacokinetics of two rectal artesunate/oral mefloquine combination regimens for the treatment of uncomplicated childhood falciparum malaria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180444

12 September 2017

The pharmacokinetics of intravenous artesunate in adults with severe falciparum malaria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180444

12 September 2017

Comparative pharmacokinetics of intramuscular artesunate and artemether in patients with severe falciparum malaria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180444

12 September 2017

Disposition of artesunate and dihydroartemisinin after administration of artesunate suppositories in children from Papua New Guinea with uncomplicated malaria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180444

12 September 2017

Protein binding and alpha : beta anomer ratio of dihydroartemisinin in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180444

12 September 2017

Intramuscular bioavailability and clinical efficacy of artesunate in gabonese children with severe malaria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180444

12 September 2017

Comparison of oral artesunate and dihydroartemisinin antimalarial bioavailabilities in acute falciparum malaria

1 reference

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12 September 2017

The pharmacokinetic properties of intramuscular artesunate and rectal dihydroartemisinin in uncomplicated falciparum malaria

1 reference

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12 September 2017

Bioavailability and preliminary clinical efficacy of intrarectal artesunate in Ghanaian children with moderate malaria

1 reference

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Pharmacokinetics and pharmacodynamics of intravenous artesunate in severe falciparum malaria.

1 reference

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12 September 2017

Antimalarial bioavailability and disposition of artesunate in acute falciparum malaria

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12 September 2017

Effects of alpha-thalassemia on pharmacokinetics of the antimalarial agent artesunate.

1 reference

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12 September 2017

A pharmacokinetic and pharmacodynamic study of intravenous vs oral artesunate in uncomplicated falciparum malaria.

1 reference

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12 September 2017

Pharmacokinetics of oral artesunate in children with moderately severe Plasmodium falciparum malaria

1 reference

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12 September 2017

Assessment of the effect of mefloquine on artesunate pharmacokinetics in healthy male volunteers

1 reference

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30 May 2018

Pharmacokinetics of artesunate following oral and rectal administration in healthy Sudanese volunteers

1 reference

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30 May 2018

Comparative pharmacokinetic study of oral and rectal formulations of artesunic acid in healthy volunteers

1 reference

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30 May 2018

Pharmacokinetic profiles of artesunate after single intravenous doses at 0.5, 1, 2, 4, and 8 mg/kg in healthy volunteers: a phase I study

1 reference

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21 January 2018

Glucuronidation of dihydroartemisinin in vivo and by human liver microsomes and expressed UDP-glucuronosyltransferases

1 reference

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21 January 2018

Pharmacokinetic and bioequivalence evaluation of two generic formulations of oral artesunate.

1 reference

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21 January 2018

Absence of time-dependent artesunate pharmacokinetics in healthy subjects during 5-day oral administration

1 reference

https://api.crossref.org/works/10.1186%2F1475-2875-10-263

21 January 2018

Pharmacokinetics of chlorproguanil, dapsone, artesunate and their major metabolites in patients during treatment of acute uncomplicated Plasmodium falciparum malaria.

1 reference

https://api.crossref.org/works/10.1186%2F1475-2875-10-263

21 January 2018

Fixed-dose pyronaridine-artesunate combination for treatment of uncomplicated falciparum malaria in pediatric patients in Gabon

1 reference

https://api.crossref.org/works/10.1186%2F1475-2875-10-263

21 January 2018

Pharmacokinetics of two paediatric artesunate mefloquine drug formulations in the treatment of uncomplicated falciparum malaria in Gabon

1 reference

https://api.crossref.org/works/10.1186%2F1475-2875-10-263

21 January 2018

Pharmacokinetics of dihydroartemisinin following oral artesunate treatment of pregnant women with acute uncomplicated falciparum malaria

1 reference

https://api.crossref.org/works/10.1186%2F1475-2875-10-263

21 January 2018

Absence of an interaction between artesunate and atovaquone--proguanil

1 reference

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Lack of impact of artesunate on the disposition kinetics of sulfadoxine/pyrimethamine when the two drugs are concomitantly administered

1 reference

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1 reference

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Investigation of bioavailability, pharmacokinetics and safety of new pediatric formulations of artesunate and mefloquine.

1 reference

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1 reference

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1 reference

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29 November 2018

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1 reference

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A pharmacokinetic and pharmacodynamic study of artesunate for vivax malaria.

1 reference

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29 November 2018

Plasma levels of artesunate and dihydroartemisinin in children with Plasmodium falciparum malaria in Gabon after administration of 50-milligram artesunate suppositories.

1 reference

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29 November 2018

Pharmacokinetics of artemisinin and artesunate after oral administration in healthy volunteers.

1 reference

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29 November 2018

Identifiers

10.1186/1475-2875-10-263

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Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

Dimensions Publication ID

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9 September 2019

https://scigraph.springernature.com/pub.10.1186/1475-2875-10-263

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PMC publication ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PubMed publication ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

ResearchGate publication ID

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