Rapid identification of phase I and II metabolites of artemisinin antimalarials using LTQ-Orbitrap hybrid mass spectrometer in combination with online hydrogen/deuterium exchange technique (Q44710554)

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English	Rapid identification of phase I and II metabolites of artemisinin antimalarials using LTQ-Orbitrap hybrid mass spectrometer in combination with online hydrogen/deuterium exchange technique	scientific article

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scholarly article

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Europe PubMed Central

PubMed publication ID

5 December 2017

Rapid identification of phase I and II metabolites of artemisinin antimalarials using LTQ-Orbitrap hybrid mass spectrometer in combination with online hydrogen/deuterium exchange technique (English)

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Europe PubMed Central

PubMed publication ID

5 December 2017

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author name string

Tian Liu

1

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Europe PubMed Central

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5 December 2017

Fuying Du

2

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5 December 2017

Yakun Wan

3

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Europe PubMed Central

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5 December 2017

Fanping Zhu

4

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5 December 2017

Jie Xing

5

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5 December 2017

publication date

1 August 2011

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5 December 2017

Journal of Mass Spectrometry

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5 December 2017

46

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5 December 2017

8

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5 December 2017

725-733

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5 December 2017

Antimalarial drug resistance

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https://api.crossref.org/works/10.1002%2FJMS.1943

21 January 2018

Possible modes of action of the artemisinin-type compounds.

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https://api.crossref.org/works/10.1002%2FJMS.1943

21 January 2018

Identification of the human cytochrome P450 enzymes involved in the in vitro metabolism of artemisinin

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https://api.crossref.org/works/10.1002%2FJMS.1943

21 January 2018

Characterisation of the human liver in vitro metabolic pattern of artemisinin and auto-induction in the rat by use of nonlinear mixed effects modelling

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https://api.crossref.org/works/10.1002%2FJMS.1943

21 January 2018

Pharmacokinetics, tissue distribution and mass balance of radiolabeled dihydroartemisinin in male rats

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https://api.crossref.org/works/10.1002%2FJMS.1943

21 January 2018

Glucuronidation of dihydroartemisinin in vivo and by human liver microsomes and expressed UDP-glucuronosyltransferases

1 reference

https://api.crossref.org/works/10.1002%2FJMS.1943

21 January 2018

Phase I and II metabolites of speciogynine, a diastereomer of the main Kratom alkaloid mitragynine, identified in rat and human urine by liquid chromatography coupled to low‐ and high‐resolution linear ion trap mass spectrometry

1 reference

https://api.crossref.org/works/10.1002%2FJMS.1943

21 January 2018

Comparison of triple quadrupole, hybrid linear ion trap triple quadrupole, time-of-flight and LTQ-Orbitrap mass spectrometers in drug discovery phase metabolite screening and identification in vitro--amitriptyline and verapamil as model compounds

1 reference

https://api.crossref.org/works/10.1002%2FJMS.1943

21 January 2018

Investigation of the in vitro metabolism of the emerging drug candidate S107 for doping-preventive purposes

1 reference

https://api.crossref.org/works/10.1002%2FJMS.1943

21 January 2018

Structural characterization of in vitro rat liver microsomal metabolites of antihistamine desloratadine using LTQ-Orbitrap hybrid mass spectrometer in combination with online hydrogen/deuterium exchange HR-LC/MS.

1 reference

https://api.crossref.org/works/10.1002%2FJMS.1943

21 January 2018

'On-the-fly' hydrogen/deuterium exchange liquid chromatography/mass spectrometry using a dual-sprayer atmospheric pressure ionisation source

1 reference

https://api.crossref.org/works/10.1002%2FJMS.1943

21 January 2018

Strategies for characterization of drug metabolites using liquid chromatography-tandem mass spectrometry in conjunction with chemical derivatization and on-line H/D exchange approaches

1 reference

https://api.crossref.org/works/10.1002%2FJMS.1943

21 January 2018

Identifiers

10.1002/JMS.1943

1 reference

Europe PubMed Central

PubMed publication ID

5 December 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

5 December 2017

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