The co-existence of transcriptional activator and transcriptional repressor MEF2 complexes influences tumor aggressiveness. (Q33626781)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28419090%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

title

The co-existence of transcriptional activator and transcriptional repressor MEF2 complexes influences tumor aggressiveness (English)

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18 March 2020

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18 March 2020

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18 March 2020

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18 March 2020

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18 March 2020

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18 March 2020

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18 March 2020

Elisa Franforte

1 reference

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18 March 2020

Sebastiano Cefalù

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18 March 2020

Sabrina Rossi

1 reference

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18 March 2020

Roberta Maestro

1 reference

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18 March 2020

Harikrishnareddy Paluvai

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18 March 2020

publication date

18 April 2017

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18 March 2020

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18 March 2020

volume

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18 March 2020

issue

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18 March 2020

page(s)

e1006752

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Creative Commons Attribution 4.0 International

18 March 2020

start time

18 April 2017

1 reference

April 2022 Public Data File from Crossref

copyrighted

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cites work

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MEF2C and EBF1 Co-regulate B Cell-Specific Transcription

21 June 2018

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Exome Sequencing of Uterine Leiomyosarcomas Identifies Frequent Mutations in TP53, ATRX, and MED12.

21 June 2018

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Regulation of class IIa HDAC activities: it is not only matter of subcellular localization

21 June 2018

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Essential control of early B-cell development by Mef2 transcription factors

21 June 2018

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RBFox1-mediated RNA splicing regulates cardiac hypertrophy and heart failure

21 June 2018

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Transcriptome sequencing identifies ETV6-NTRK3 as a gene fusion involved in GIST.

21 June 2018

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MEF2 transcription factors: developmental regulators and emerging cancer genes

21 June 2018

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Autism-Associated Chromatin Regulator Brg1/SmarcA4 Is Required for Synapse Development and Myocyte Enhancer Factor 2-Mediated Synapse Remodeling

21 June 2018

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MSX2 mediates entry of human pluripotent stem cells into mesendoderm by simultaneously suppressing SOX2 and activating NODAL signaling

21 June 2018

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The MEF2-HDAC axis controls proliferation of mammary epithelial cells and acini formation in vitro.

21 June 2018

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MEF2B mutations in non-Hodgkin lymphoma dysregulate cell migration by decreasing MEF2B target gene activation

21 June 2018

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MEF2D drives photoreceptor development through a genome-wide competition for tissue-specific enhancers

21 June 2018

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Phosphorylation-dependent degradation of MEF2C contributes to regulate G2/M transition

21 June 2018

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The control operated by the cell cycle machinery on MEF2 stability contributes to the downregulation of CDKN1A and entry into S phase

21 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5413110

limma powers differential expression analyses for RNA-sequencing and microarray studies

21 June 2018

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MEF2 transcription factors regulate distinct gene programs in mammalian skeletal muscle differentiation

21 June 2018

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Alternative splicing of MEF2C pre-mRNA controls its activity in normal myogenesis and promotes tumorigenicity in rhabdomyosarcoma cells

21 June 2018

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Transcriptomic analysis unveils correlations between regulative apoptotic caspases and genes of cholesterol homeostasis in human brain

21 June 2018

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KDM5 interacts with Foxo to modulate cellular levels of oxidative stress

21 June 2018

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21 June 2018

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Global MEF2 target gene analysis in cardiac and skeletal muscle reveals novel regulation of DUSP6 by p38MAPK-MEF2 signaling

21 June 2018

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Requirement of MEF2A, C, and D for skeletal muscle regeneration

21 June 2018

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Overexpression of the transcription factor MEF2D in hepatocellular carcinoma sustains malignant character by suppressing G2-M transition genes.

21 June 2018

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Loss of MEF2D expression inhibits differentiation and contributes to oncogenesis in rhabdomyosarcoma cells

21 June 2018

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Modulation of lysine methylation in myocyte enhancer factor 2 during skeletal muscle cell differentiation.

21 June 2018

1 reference

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MEF2 is a converging hub for histone deacetylase 4 and phosphatidylinositol 3-kinase/Akt-induced transformation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5413110

Double nicking by RNA-guided CRISPR Cas9 for enhanced genome editing specificity

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5413110

MEF2B mutations lead to deregulated expression of the oncogene BCL6 in diffuse large B cell lymphoma

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5413110

Tissue-specific splicing of a ubiquitously expressed transcription factor is essential for muscle differentiation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5413110

Identifying targets for the restoration and reactivation of BRM.

21 June 2018

1 reference

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An integrated encyclopedia of DNA elements in the human genome

21 June 2018

1 reference

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The cBio cancer genomics portal: an open platform for exploring multidimensional cancer genomics data

21 June 2018

1 reference

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New therapeutic targets in soft tissue sarcoma

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5413110

RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genome

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5413110

To repress or not to repress: This is the guardian's question

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5413110

Structure of p300 bound to MEF2 on DNA reveals a mechanism of enhanceosome assembly

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5413110

Ubiquitin-dependent degradation of HDAC4, a new regulator of random cell motility.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5413110

Soft tissue sarcomas with complex genomic profiles

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5413110

Homing and invasiveness of MLL/ENL leukemic cells is regulated by MEF2C.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5413110

p38 MAPK signaling regulates recruitment of Ash2L-containing methyltransferase complexes to specific genes during differentiation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5413110

MEF2: a central regulator of diverse developmental programs

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5413110

Cooperative transformation by MEF2D/DAZAP1 and DAZAP1/MEF2D fusion proteins generated by the variant t(1;19) in acute lymphoblastic leukemia

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5413110

Regulation of skeletal muscle sarcomere integrity and postnatal muscle function by Mef2c

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5413110

Breast cancer associated transcriptional repressor PLU-1/JARID1B interacts directly with histone deacetylases

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5413110

Activity-dependent regulation of MEF2 transcription factors suppresses excitatory synapse number

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5413110

Caspase-dependent regulation of histone deacetylase 4 nuclear-cytoplasmic shuttling promotes apoptosis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5413110

Sequence-specific recruitment of transcriptional co-repressor Cabin1 by myocyte enhancer factor-2

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5413110

A splice variant of Skp2 is retained in the cytoplasm and fails to direct cyclin D1 ubiquitination in the uterine cancer cell line SK-UT.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5413110

MEF2 is upregulated during cardiac hypertrophy and is required for normal post-natal growth of the myocardium

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5413110

HDAC4 deacetylase associates with and represses the MEF2 transcription factor

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5413110

MEF-2 function is modified by a novel co-repressor, MITR

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5413110

Determination of the consensus binding site for MEF2 expressed in muscle and brain reveals tissue-specific sequence constraints

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5413110

Dynamic Phosphorylation of the Myocyte Enhancer Factor 2Cα1 Splice Variant Promotes Skeletal Muscle Regeneration and Hypertrophy

21 June 2018

1 reference

Crossref

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1006752

MEF2 negatively regulates learning-induced structural plasticity and memory formation

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1006752

Integrated transcript and genome analyses reveal NKX2-1 and MEF2C as potential oncogenes in T cell acute lymphoblastic leukemia

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1006752

Myocyte enhancer factor 2C regulation of hepatocellular carcinoma via vascular endothelial growth factor and Wnt/β-catenin signaling

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28419090

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Overexpression of myocyte enhancer factor 2 and histone hyperacetylation in hepatocellular carcinoma

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28419090

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PGEN.1006752

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28419090%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28419090%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

PubMed publication ID

28419090

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28419090%20AND%20SRC:MED&resulttype=core&format=json