Soft tissue sarcomas with complex genomic profiles (Q34617586)

3 August 2017

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title

Soft tissue sarcomas with complex genomic profiles (English)

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3 August 2017

Louis Guillou

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3 August 2017

Alain Aurias

series ordinal

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3 August 2017

publication date

1 February 2010

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3 August 2017

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3 August 2017

volume

456

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3 August 2017

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3 August 2017

page(s)

201-217

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Correlation between clinicopathological features and karyotype in spindle cell sarcomas. A report of 130 cases from the CHAMP study group

3 August 2017

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Tumor suppressor mutations and growth factor signaling in the pathogenesis of NF1-associated peripheral nerve sheath tumors. I. The role of tumor suppressor mutations

21 January 2018

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MDM-2 oncoprotein overexpression, p53 gene mutation, and VEGF up-regulation in angiosarcomas

21 January 2018

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Sarcoma after radiation therapy: retrospective multiinstitutional study of 80 histologically confirmed cases. Radiation Therapist and Pathologist Groups of the Fédération Nationale des Centres de Lutte Contre le Cancer

21 January 2018

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Cytogenetic characterization of peripheral nerve sheath tumours: a report of the CHAMP study group

21 January 2018

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12 December 2020

Dedifferentiated liposarcomas with divergent myosarcomatous differentiation developed in the internal trunk: a study of 27 cases and comparison to conventional dedifferentiated liposarcomas and leiomyosarcomas

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12 December 2020

Updates on the cytogenetics and molecular genetics of bone and soft tissue tumors: liposarcoma

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12 December 2020

Genomic signatures of chromosomal instability and osteosarcoma progression detected by high resolution array CGH and interphase FISH.

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12 December 2020

Leiomyosarcomas and most malignant fibrous histiocytomas share very similar comparative genomic hybridization imbalances: an analysis of a series of 27 leiomyosarcomas

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12 December 2020

Myxofibrosarcoma. Clinicopathologic analysis of 75 cases with emphasis on the low-grade variant

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12 December 2020

Evaluation of biological potential of smooth muscle tumours

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12 December 2020

Updates on the cytogenetics and molecular genetics of bone and soft tissue tumors: osteosarcoma and related tumors

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12 December 2020

Prognostic significance of ezrin expression in pleomorphic malignant fibrous histiocytoma.

1 reference

12 December 2020

Prognostic factors of myxofibrosarcomas: implications of margin status, tumor necrosis, and mitotic rate on survival

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12 December 2020

Allelic loss of 3 different tumor suppressor gene loci in benign and malignant endothelial tumors of the head and neck.

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12 December 2020

Extraskeletal osteosarcomas: a clinicopathologic study of 25 cases

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12 December 2020

Spectral karyotyping identifies recurrent complex rearrangements of chromosomes 8, 17, and 20 in osteosarcomas

1 reference

12 December 2020

High-resolution DNA copy number profiling of malignant peripheral nerve sheath tumors using targeted microarray-based comparative genomic hybridization.

1 reference

12 December 2020

Acral myxoinflammatory fibroblastic sarcoma with unique clonal chromosomal changes

1 reference

12 December 2020

Myxoinflammatory fibroblastic sarcoma: investigations by comparative genomic hybridization of two cases and review of the literature.

1 reference

12 December 2020

Pleomorphic rhabdomyosarcoma in children: four cases in the pediatric age group

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12 December 2020

Epstein-Barr virus-associated smooth muscle tumors are distinctive mesenchymal tumors reflecting multiple infection events: a clinicopathologic and molecular analysis of 29 tumors from 19 patients

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12 December 2020

Cellular/intramuscular myxoma and grade I myxofibrosarcoma are characterized by distinct genetic alterations and specific composition of their extracellular matrix

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12 December 2020

DNA hypermethylation status of multiple genes in soft tissue sarcomas

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12 December 2020

Proteomic signatures corresponding to histological classification and grading of soft-tissue sarcomas

1 reference

12 December 2020

Pleomorphic malignant fibrous histiocytoma: fact or fiction? A critical reappraisal based on 159 tumors diagnosed as pleomorphic sarcoma

1 reference

12 December 2020

Myxoinflammatory fibroblastic sarcoma showing t(2;6)(q31;p21.3) as a sole cytogenetic abnormality.

1 reference

12 December 2020

Primary liposarcoma of the skin: a rare neoplasm with unusual high grade features

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12 December 2020

Acral myxoinflammatory fibroblastic sarcoma: a low-grade tumor of the hands and feet

1 reference

12 December 2020

Clinicopathologic re-evaluation of 100 malignant fibrous histiocytomas: prognostic relevance of subclassification

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12 December 2020

Loss of 13q14-q21 and gain of 5p14-pter in the progression of leiomyosarcoma.

1 reference

12 December 2020

Myxofibrosarcoma. A malignant soft tissue tumor of fibroblastic-histiocytic origin. A clinicopathologic and prognostic study of 110 cases using multivariate analysis

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12 December 2020

The RB1 gene is the target of chromosome 13 deletions in malignant fibrous histiocytoma

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12 December 2020

Pleomorphic liposarcoma: clinicopathologic, immunohistochemical, and follow-up analysis of 63 cases: a study from the French Federation of Cancer Centers Sarcoma Group

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12 December 2020

The role of mTOR inhibitors for treatment of sarcomas

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12 December 2020

Postirradiation sarcoma. Analysis of a nationwide cancer registry material

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12 December 2020

Genetic aberrations in soft tissue leiomyosarcoma

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12 December 2020

Two genetic pathways, t(1;10) and amplification of 3p11-12, in myxoinflammatory fibroblastic sarcoma, haemosiderotic fibrolipomatous tumour, and morphologically similar lesions.

1 reference

12 December 2020

Myofibroblastic differentiation in malignant fibrous histiocytoma (pleomorphic myofibrosarcoma): a clinicopathological study.

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12 December 2020

Mutation of the p53 gene in postradiation sarcoma

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12 December 2020

Inflammatory myxohyaline tumor of distal extremities with virocyte or Reed-Sternberg-like cells: a distinctive lesion with features simulating inflammatory conditions, Hodgkin's disease, and various sarcomas

1 reference

12 December 2020

Functional copy-number alterations in cancer

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12 December 2020

Chromosomal imbalances in pleomorphic rhabdomyosarcomas and identification of the alveolar rhabdomyosarcoma-associated PAX3-FOXO1A fusion gene in one case

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12 December 2020

Frequent amplification and rearrangement of chromosomal bands 6p12-p21 and 17p11.2 in osteosarcoma

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12 December 2020

Postradiation soft tissue sarcomas. An analysis of 53 cases

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12 December 2020

Distinct chromosomal imbalances in pleomorphic and in high-grade dedifferentiated liposarcomas

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12 December 2020

Myoid differentiation and prognosis in adult pleomorphic sarcomas of the extremity: an analysis of 92 cases

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12 December 2020

The TOR pathway: a target for cancer therapy

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12 December 2020

Classification of pleomorphic sarcomas: where are we now?

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12 December 2020

Recurrent chromosomal imbalances and structurally abnormal breakpoints within complex karyotypes of malignant peripheral nerve sheath tumour and malignant triton tumour: a cytogenetic and molecular cytogenetic study.

1 reference

12 December 2020

Low-grade myxofibrosarcoma: a clinicopathologic analysis of 49 cases treated at a single institution with simultaneous assessment of the efficacy of 3-tier and 4-tier grading systems

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12 December 2020

Prognostic impact of immunohistochemical expression of ezrin in highly malignant soft tissue sarcomas

1 reference

12 December 2020

The evolving classification of soft tissue tumours: an update based on the new WHO classification

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12 December 2020

Epithelioid variant of myxofibrosarcoma: expanding the clinicomorphologic spectrum of myxofibrosarcoma in a series of 17 cases

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12 December 2020

Gains of 13q are correlated with a poor prognosis in liposarcoma

1 reference

12 December 2020

Updates on the cytogenetics and molecular genetics of bone and soft tissue tumors: leiomyosarcoma

1 reference

12 December 2020

Extraosseous osteosarcoma: response to treatment and long-term outcome

1 reference

12 December 2020

Adult rhabdomyosarcoma: outcome following multimodality treatment

1 reference

12 December 2020

DNA copy number changes in high-grade malignant peripheral nerve sheath tumors by array CGH.

1 reference

12 December 2020

Cytogenetic analysis of 46 pleomorphic soft tissue sarcomas and correlation with morphologic and clinical features: a report of the CHAMP Study Group. Chromosomes and MorPhology.

1 reference

12 December 2020

Identification of a novel amplicon at distal 17q containing the BIRC5/SURVIVIN gene in malignant peripheral nerve sheath tumours

1 reference

12 December 2020

Derivation of sarcomas from mesenchymal stem cells via inactivation of the Wnt pathway

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12 December 2020

Radiation-associated sarcomas are characterized by complex karyotypes with frequent rearrangements of chromosome arm 3p

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12 December 2020

Local recurrence of myxofibrosarcoma is associated with increase in tumour grade and cytogenetic aberrations, suggesting a multistep tumour progression model

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12 December 2020

Expression of the FUS-CHOP fusion protein in primary mesenchymal progenitor cells gives rise to a model of myxoid liposarcoma.

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12 December 2020

Cytogenetic characterization of six malignant peripheral nerve sheath tumors: comparison of karyotyping and comparative genomic hybridization

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12 December 2020

Myxoid malignant fibrous histiocytoma and pleomorphic liposarcoma share very similar genomic imbalances

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12 December 2020

Alterations of cancer-related genes in soft tissue sarcomas: hypermethylation of RASSF1A is frequently detected in leiomyosarcoma and associated with poor prognosis in sarcoma.

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12 December 2020

Gene expression analysis of human soft tissue leiomyosarcomas

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12 December 2020

Molecular pathogenesis of uterine smooth muscle tumors from transcriptional profiling

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12 December 2020

Expression of hypoxia-inducible factor (HIF)-1alpha as a biomarker of outcome in soft-tissue sarcomas

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12 December 2020

Cytogenetic findings in 73 osteosarcoma specimens and a review of the literature

1 reference

12 December 2020

Rhabdomyosarcomas in adults and children: an update

1 reference

12 December 2020

Pleomorphic rhabdomyosarcoma in adults: a clinicopathologic study of 38 cases with emphasis on morphologic variants and recent skeletal muscle-specific markers

1 reference

12 December 2020

Sporadic and Thorotrast-induced angiosarcomas of the liver manifest frequent and multiple point mutations in K-ras-2.

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12 December 2020

Cytogenetic and real-time quantitative reverse-transcriptase polymerase chain reaction analyses in pleomorphic rhabdomyosarcoma.

1 reference

12 December 2020

Cytogenetic aberrations and DNA ploidy in soft tissue sarcoma. A Southwest Oncology Group Study

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12 December 2020

Microarray-based copy number and expression profiling in dedifferentiated and pleomorphic liposarcoma

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12 December 2020

Strong smooth muscle differentiation is dependent on myocardin gene amplification in most human retroperitoneal leiomyosarcomas.

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12 December 2020

Development of Ewing's sarcoma from primary bone marrow-derived mesenchymal progenitor cells

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12 December 2020

Frequent amplifications and abundant expression of TRIO, NKD2, and IRX2 in soft tissue sarcomas

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12 December 2020

Ezrin, a key component in tumor metastasis

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12 December 2020

Comparative cytogenetic study of spindle cell and pleomorphic leiomyosarcomas of soft tissues: a report from the CHAMP Study Group

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12 December 2020

A gene expression signature associated with metastatic outcome in human leiomyosarcomas.

1 reference

12 December 2020

Pleomorphic liposarcoma: clinicopathologic analysis of 57 cases

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12 December 2020

Absence of Epstein-Barr virus (EBV) in a gastrointestinal stromal cell tumour (GIST) in an adult human immunodeficiency virus-seropositive patient with past EBV infection

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12 December 2020

Gene expression profiling of liposarcoma identifies distinct biological types/subtypes and potential therapeutic targets in well-differentiated and dedifferentiated liposarcoma.

1 reference

12 December 2020

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12 December 2020

A developmental model of sarcomagenesis defines a differentiation-based classification for liposarcomas.

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12 December 2020

Genomic imbalances of 7p and 17q in malignant peripheral nerve sheath tumors are clinically relevant

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12 December 2020

Epithelioid variant of pleomorphic liposarcoma: a study of 12 cases of a distinctive variant of high-grade liposarcoma

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12 December 2020

Indistinguishable genomic profiles and shared prognostic markers in undifferentiated pleomorphic sarcoma and leiomyosarcoma: different sides of a single coin?

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12 December 2020

Tumor suppressor genes and related molecules in leiomyosarcoma

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12 December 2020

The AKT-mTOR pathway plays a critical role in the development of leiomyosarcomas

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12 December 2020

Myxoinflammatory fibroblastic sarcoma with complex supernumerary ring chromosomes composed of chromosome 3 segments

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12 December 2020

Diagnostic and prognostic gene expression signatures in 177 soft tissue sarcomas: hypoxia-induced transcription profile signifies metastatic potential

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12 December 2020

Global protein-expression analysis of bone and soft tissue sarcomas

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12 December 2020

Gene expression analysis of soft tissue sarcomas: characterization and reclassification of malignant fibrous histiocytoma.

1 reference

12 December 2020

Clinicopathologic features and treatment of postirradiation sarcoma of bone and soft tissue

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12 December 2020

Loss of chromosome 13 is the most frequent genomic imbalance in malignant fibrous histiocytomas. A comparative genomic hybridization analysis of a series of 30 cases

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12 December 2020

Does comparative genomic hybridization reveal distinct differences in DNA copy number sequence patterns between leiomyosarcoma and malignant fibrous histiocytoma?

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12 December 2020

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12 December 2020

Loss of DNA copy number of 10q is associated with aggressive behavior of leiomyosarcomas: a comparative genomic hybridization study

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12 December 2020

Mechanisms of inactivation of the p16INK4a gene in leiomyosarcoma of soft tissue: decreased p16 expression correlates with promoter methylation and poor prognosis

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12 December 2020

Topoisomerase-II alpha is upregulated in malignant peripheral nerve sheath tumors and associated with clinical outcome

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12 December 2020

Mutations of p53 tumor-suppressor gene in angiosarcoma

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12 December 2020

10.1007/S00428-009-0853-4

Identifiers

DOI

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3 August 2017

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