Methods for identifying compounds that specifically target translation (Q33301975)

25 July 2017

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title

Methods for identifying compounds that specifically target translation (English)

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25 July 2017

Pohl Milon

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Attilio Fabbretti

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Claudio O Gualerzi

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25 July 2017

Cynthia L Pon

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25 July 2017

Letizia Brandi

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25 July 2017

Marcello Carotti

series ordinal

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25 July 2017

language of work or name

English

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publication date

1 January 2007

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25 July 2017

published in

Methods in Enzymology

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25 July 2017

volume

431

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25 July 2017

page(s)

229-267

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Antibacterial drug discovery and structure-based design

25 July 2017

cites work

1 reference

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7 January 2021

New class of bacterial phenylalanyl-tRNA synthetase inhibitors with high potency and broad-spectrum activity

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7 January 2021

The translation initiation functions of IF2: targets for thiostrepton inhibition.

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7 January 2021

Characterization of GE82832, a peptide inhibitor of translocation interacting with bacterial 30S ribosomal subunits

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7 January 2021

Specific, efficient, and selective inhibition of prokaryotic translation initiation by a novel peptide antibiotic

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7 January 2021

Antibacterial drug discovery in the 21st century

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7 January 2021

Chemical synthesis and in vivo hyperexpression of a modular gene coding for Escherichia coli translational initiation factor IF1.

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7 January 2021

Selection of the mRNA translation initiation region by Escherichia coli ribosomes

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7 January 2021

Translation initiation factor IF2 interacts with the 30 S ribosomal subunit via two separate binding sites

1 reference

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7 January 2021

Cell-based assays to detect inhibitors of fungal mRNA capping enzymes and characterization of sinefungin as a cap methyltransferase inhibitor

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7 January 2021

On the fidelity of mRNA translation in the nuclease-treated rabbit reticulocyte lysate system

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7 January 2021

Development of a high-throughput scintillation proximity assay for the identification of C-domain translational initiation factor 2 inhibitors

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7 January 2021

Sordarin inhibits fungal protein synthesis by blocking translocation differently to fusidic acid

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7 January 2021

Novel assays and novel strains - promising routes to new antibiotics?

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7 January 2021

Contribution of cotranslational folding to the rate of formation of native protein structure

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7 January 2021

Characterization of cap structures.

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7 January 2021

A general procedure for the isolation of specific transfer ribonucleic acids

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7 January 2021

Preferential translation of cold-shock mRNAs during cold adaptation

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7 January 2021

Cold-stress-induced de novo expression of infC and role of IF3 in cold-shock translational bias

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7 January 2021

Initiation factors in the early events of mRNA translation in bacteria

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7 January 2021

Mapping the fMet-tRNA(f)(Met) binding site of initiation factor IF2.

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7 January 2021

N-alkyl urea hydroxamic acids as a new class of peptide deformylase inhibitors with antibacterial activity

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7 January 2021

Giardia lamblia RNA cap guanine-N2 methyltransferase (Tgs2).

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7 January 2021

Interaction of pseudomonic acid A with Escherichia coli B isoleucyl-tRNA synthetase

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7 January 2021

Characterization of mammalian eIF4E-family members

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7 January 2021

Aminoacyl-tRNA synthetases and their inhibitors as a novel family of antibiotics

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7 January 2021

Co-translational Folding of an Eukaryotic Multidomain Protein in a Prokaryotic Translation System

1 reference

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7 January 2021

Translation of mRNAs with degenerate initiation triplet AUU displays high initiation factor 2 dependence and is subject to initiation factor 3 repression

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7 January 2021

Malignant transformation by a eukaryotic initiation factor subunit that binds to mRNA 5' cap

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7 January 2021

Isolation and expression of a cDNA encoding Renilla reniformis luciferase

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7 January 2021

A convenient, rapid and sensitive method for measuring the incorporation of radioactive amino acids into protein

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7 January 2021

The nucleotide-binding site of bacterial translation initiation factor 2 (IF2) as a metabolic sensor

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7 January 2021

Transient kinetics, fluorescence, and FRET in studies of initiation of translation in bacteria

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7 January 2021

Small-molecule inhibition of the interaction between the translation initiation factors eIF4E and eIF4G

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7 January 2021

Specific interaction of initiation factor IF2 of E. coli with formylmethionyl-tRNAfMet

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7 January 2021

The bacterial ribosome as a target for antibiotics

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7 January 2021

New aminoacyl-tRNA synthetase inhibitors as antibacterial agents

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7 January 2021

Why is big Pharma getting out of antibacterial drug discovery?

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7 January 2021

Species-specific inhibition of fungal protein synthesis by sordarin: identification of a sordarin-specificity region in eukaryotic elongation factor 2.

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7 January 2021

The mRNA capping apparatus as drug target and guide to eukaryotic phylogeny

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7 January 2021

Sordarin derivatives induce a novel conformation of the yeast ribosome translocation factor eEF2

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7 January 2021

The C-terminal subdomain (IF2 C-2) contains the entire fMet-tRNA binding site of initiation factor IF2.

1 reference

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7 January 2021

Where will new antibiotics come from?

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7 January 2021

Platensimycin is a selective FabF inhibitor with potent antibiotic properties

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7 January 2021

Discovery of FabH/FabF inhibitors from natural products

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7 January 2021

10.1016/S0076-6879(07)31012-4

Identifiers

DOI

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release_4clam7xu2jbj7elh4qopl7tlvq

25 July 2017

Fatcat ID

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Fatcat

https://api.fatcat.wiki/v0/release/4clam7xu2jbj7elh4qopl7tlvq

24 November 2022

mapped directly with Wikidata item

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