New class of bacterial phenylalanyl-tRNA synthetase inhibitors with high potency and broad-spectrum activity (Q35547361)

8 August 2017

title

New class of bacterial phenylalanyl-tRNA synthetase inhibitors with high potency and broad-spectrum activity (English)

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8 August 2017

Dieter Beyer

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8 August 2017

Hein-Peter Kroll

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8 August 2017

Rainer Endermann

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8 August 2017

Guido Schiffer

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8 August 2017

Stephan Siegel

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8 August 2017

Marcus Bauser

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8 August 2017

Jens Pohlmann

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8 August 2017

Michael Brands

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8 August 2017

Karl Ziegelbauer

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8 August 2017

Dieter Haebich

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8 August 2017

Christine Eymann

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8 August 2017

Heike Brötz-Oesterhelt

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8 August 2017

language of work or name

English

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publication date

1 February 2004

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Antimicrobial Agents and Chemotherapy

8 August 2017

published in

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8 August 2017

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8 August 2017

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8 August 2017

page(s)

525-532

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Amino acid transfer from aminoacyl-ribonucleic acids to protein on ribosomes of Escherichia coli

8 August 2017

cites work

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12 July 2018

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12 July 2018

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Expression and characterization of a human mitochondrial phenylalanyl-tRNA synthetase

12 July 2018

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Crystal structures of phenylalanyl-tRNA synthetase complexed with phenylalanine and a phenylalanyl-adenylate analogue

12 July 2018

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Human phenylalanyl-tRNA synthetase: cloning, characterization of the deduced amino acid sequences in terms of the structural domains and coordinately regulated expression of the alpha and beta subunits in chronic myeloid leukemia cells

12 July 2018

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Aminoacyl-tRNA synthetases in biology and disease: new evidence for structural and functional diversity in an ancient family of enzymes

12 July 2018

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The crystal structure of phenylalanyl-tRNA synthetase from thermus thermophilus complexed with cognate tRNAPhe

12 July 2018

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SB 205952, a novel semisynthetic monic acid analog with at least two modes of action

12 July 2018

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Root of the universal tree of life based on ancient aminoacyl-tRNA synthetase gene duplications

12 July 2018

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Structure of phenylalanyl-tRNA synthetase from Thermus thermophilus

12 July 2018

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Isolation of "relaxed" mutants of Escherichia coli

12 July 2018

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Amino acid substrate specificity of Escherichia coli phenylalanyl-tRNA synthetase altered by distinct mutations.

12 July 2018

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Evolution of aminoacyl-tRNA synthetase quaternary structure and activity: Saccharomyces cerevisiae mitochondrial phenylalanyl-tRNA synthetase

12 July 2018

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Amino acids are not all initially attached to the same position on transfer RNA molecules

12 July 2018

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Inhibition of phenylalanine tRNA synthetase fromBacillus subtilisby ochratoxin A

12 July 2018

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Inhibition of isoleucyl-transfer ribonucleic acid synthetase in Echerichia coli by pseudomonic acid

12 July 2018

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A study of the genetic material determining an enzyme activity in Pneumococcus

12 July 2018

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Molecular and functional properties of an archaeal phenylalanyl-tRNA synthetase from the hyperthermophile Sulfolobus solfataricus

26 September 2018

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Aminoacyl tRNA synthetases as targets for new anti-infectives.

26 September 2018

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Substrate specificity is determined by amino acid binding pocket size in Escherichia coli phenylalanyl-tRNA synthetase

26 September 2018

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Increased rates of tRNA charging through modification of the enzyme-aminoacyl-adenylate complex of phenylalanyl-tRNA synthetase.

26 September 2018

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Catalytic mechanism of phenylalanyl-tRNA synthetase of Escherichia coli K10. Conformational change and tRNAPhe phenylalanylation are concerted

26 September 2018

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12 December 2020

Kinetic properties of pure overproduced Bacillus subtilis phenylalanyl-tRNA synthetase do not favour its in vivo inhibition by ochratoxin A

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12 December 2020

Amino acid distribution in human blood. A significant pool of amino acids is adsorbed onto blood cell membranes

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12 December 2020

Purification and substrate specificity of a phenylalanine-activating enzyme from Escherichia coli 9723

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12 December 2020

ION EXCHANGE CHROMATOGRAPHY OF THE FREE AMINO ACIDS IN THE PLASMA OF THE NEWBORN INFANT

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12 December 2020

Measurement of blood plasma amino acids in ultrafiltrates by high-performance liquid chromatography with automatic precolumn O-phthaldialdehyde derivatization

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12 December 2020

Pseudomonic Acid: an Antibiotic produced by Pseudomonas fluorescens

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12 December 2020

Phenylalanyl transfer ribonucleic acid synthetase from Escherichia coli B. Potent inhibition by analogues of N-benzyl-2-phenylethylamine

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12 December 2020

Phenylalanyl transfer ribonucleic acid synthetase from rat liver. Analysis of phenylalanine and adenosine 5'-triphosphate binding sites and comparison to the enzyme from Escherichia coli

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12 December 2020

10.1128/AAC.48.2.525-532.2004

Identifiers

DOI

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8 August 2017

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8 August 2017

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