T-cell metabolism governing activation, proliferation and differentiation; a modular view (Q38915095)

7 September 2017

1 reference

title

T-cell metabolism governing activation, proliferation and differentiation; a modular view (English)

1 reference

7 September 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27479920%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

author name string

Anne-Valérie Burgener

series ordinal

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27479920%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Jasmin Grählert

series ordinal

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27479920%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Christoph Hess

series ordinal

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27479920%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

publication date

1 August 2016

1 reference

7 September 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27479920%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

volume

150

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27479920%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

issue

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27479920%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

page(s)

35-44

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27479920%20AND%20SRC:MED&resulttype=core&format=json

The CD28 signaling pathway regulates glucose metabolism

11 June 2020

cites work

1 reference

On the Origin of Cancer Cells

21 January 2018

1 reference

Aerobic glycolysis: meeting the metabolic requirements of cell proliferation

21 January 2018

1 reference

Glucose uptake is limiting in T cell activation and requires CD28-mediated Akt-dependent and independent pathways.

21 January 2018

1 reference

Regulation of T lymphocyte metabolism

21 January 2018

1 reference

HIF1alpha-dependent glycolytic pathway orchestrates a metabolic checkpoint for the differentiation of TH17 and Treg cells

21 January 2018

1 reference

Rapid effector function of memory CD8+ T cells requires an immediate-early glycolytic switch

21 January 2018

1 reference

Complement Regulates Nutrient Influx and Metabolic Reprogramming during Th1 Cell Responses

21 January 2018

1 reference

21 January 2018

1 reference

The transcription factor Myc controls metabolic reprogramming upon T lymphocyte activation

21 January 2018

1 reference

Single cell tuning of Myc expression by antigen receptor signal strength and interleukin-2 in T lymphocytes.

21 January 2018

1 reference

The transcription factor IRF4 is essential for TCR affinity-mediated metabolic programming and clonal expansion of T cells

21 January 2018

1 reference

Notch controls the survival of memory CD4+ T cells by regulating glucose uptake

21 January 2018

1 reference

The Immune-Metabolic Basis of Effector Memory CD4+ T Cell Function under Hypoxic Conditions

21 January 2018

1 reference

Posttranscriptional control of T cell effector function by aerobic glycolysis

21 January 2018

1 reference

Metabolic programming and PDHK1 control CD4+ T cell subsets and inflammation

21 January 2018

1 reference

Cutting edge: distinct glycolytic and lipid oxidative metabolic programs are essential for effector and regulatory CD4+ T cell subsets.

21 January 2018

1 reference

Glycolysis controls the induction of human regulatory T cells by modulating the expression of FOXP3 exon 2 splicing variants

21 January 2018

1 reference

The Proteomic Landscape of Human Ex Vivo Regulatory and Conventional T Cells Reveals Specific Metabolic Requirements

21 January 2018

1 reference

The role of low-level lactate production in airway inflammation in asthma

21 January 2018

1 reference

Increased glucose metabolic activity is associated with CD4+ T-cell activation and depletion during chronic HIV infection

21 January 2018

1 reference

Normalization of CD4+ T cell metabolism reverses lupus

21 January 2018

1 reference

Preventing Allograft Rejection by Targeting Immune Metabolism

21 January 2018

1 reference

Phosphofructokinase deficiency impairs ATP generation, autophagy, and redox balance in rheumatoid arthritis T cells

21 January 2018

1 reference

Metabolic Competition in the Tumor Microenvironment Is a Driver of Cancer Progression

21 January 2018

1 reference

Phosphoenolpyruvate Is a Metabolic Checkpoint of Anti-tumor T Cell Responses.

21 January 2018

1 reference

Cancer mediates effector T cell dysfunction by targeting microRNAs and EZH2 via glycolysis restriction.

21 January 2018

1 reference

PD-1 alters T-cell metabolic reprogramming by inhibiting glycolysis and promoting lipolysis and fatty acid oxidation

21 January 2018

1 reference

Glucose Oxidation Is Critical for CD4+ T Cell Activation in a Mouse Model of Systemic Lupus Erythematosus.

21 January 2018

1 reference

Mitochondria are required for antigen-specific T cell activation through reactive oxygen species signaling.

21 January 2018

1 reference

Inflammatory T cell responses rely on amino acid transporter ASCT2 facilitation of glutamine uptake and mTORC1 kinase activation

21 January 2018

1 reference

Glutamine uptake and metabolism are coordinately regulated by ERK/MAPK during T lymphocyte activation

21 January 2018

1 reference

Bidirectional transport of amino acids regulates mTOR and autophagy

21 January 2018

1 reference

Glutaminolysis activates Rag-mTORC1 signaling.

21 January 2018

1 reference

The energy sensor AMPK regulates T cell metabolic adaptation and effector responses in vivo

21 January 2018

1 reference

Memory CD8(+) T Cells Require Increased Concentrations of Acetate Induced by Stress for Optimal Function

21 January 2018

1 reference

Characterization of the metabolic phenotype of chronically activated lymphocytes

21 January 2018

1 reference

Manipulating the bioenergetics of alloreactive T cells causes their selective apoptosis and arrests graft-versus-host disease

21 January 2018

1 reference

Effector T cells require fatty acid metabolism during murine graft-versus-host disease.

21 January 2018

1 reference

Retracted: The protein LEM promotes CD8⁺ T cell immunity through effects on mitochondrial respiration

21 January 2018

1 reference

Convergence of multiple signaling pathways is required to coordinately up-regulate mtDNA and mitochondrial biogenesis during T cell activation

21 January 2018

1 reference

Mitochondrial Respiration Controls Lysosomal Function during Inflammatory T Cell Responses.

21 January 2018

1 reference

Mitochondrial respiratory capacity is a critical regulator of CD8+ T cell memory development

21 January 2018

1 reference

Enhancing CD8 T-cell memory by modulating fatty acid metabolism

21 January 2018

1 reference

Memory CD8(+) T cells use cell-intrinsic lipolysis to support the metabolic programming necessary for development.

21 January 2018

1 reference

IL-7-Induced Glycerol Transport and TAG Synthesis Promotes Memory CD8+ T Cell Longevity

21 January 2018

1 reference

CD8 memory T cells have a bioenergetic advantage that underlies their rapid recall ability.

21 January 2018

1 reference

p38 signaling inhibits mTORC1-independent autophagy in senescent human CD8⁺ T cells

21 January 2018

1 reference

Mitochondrial Dynamics Controls T Cell Fate through Metabolic Programming.

21 January 2018

1 reference

Fine-Tuning of CD8(+) T Cell Mitochondrial Metabolism by the Respiratory Chain Repressor MCJ Dictates Protection to Influenza Virus

21 January 2018

1 reference

Control of amino-acid transport by antigen receptors coordinates the metabolic reprogramming essential for T cell differentiation

21 January 2018

1 reference

Rheb binding to mammalian target of rapamycin (mTOR) is regulated by amino acid sufficiency

21 January 2018

1 reference

Ragulator-Rag complex targets mTORC1 to the lysosomal surface and is necessary for its activation by amino acids

21 January 2018

1 reference

Ragulator is a GEF for the rag GTPases that signal amino acid levels to mTORC1

21 January 2018

1 reference

Structural basis for leucine sensing by the Sestrin2-mTORC1 pathway

21 January 2018

1 reference

Sestrin2 is a leucine sensor for the mTORC1 pathway

21 January 2018

1 reference

The CASTOR Proteins Are Arginine Sensors for the mTORC1 Pathway

21 January 2018

1 reference

Metabolic maintenance of cell asymmetry following division in activated T lymphocytes

21 January 2018

1 reference

Asymmetric inheritance of mTORC1 kinase activity during division dictates CD8(+) T cell differentiation

21 January 2018

1 reference

Suppression of T-cell functions by human granulocyte arginase

21 January 2018

1 reference

Metabolic regulation of hepatitis B immunopathology by myeloid-derived suppressor cells.

21 January 2018

1 reference

Local suppression of T cell responses by arginase-induced L-arginine depletion in nonhealing leishmaniasis

21 January 2018

1 reference

Arginine depletion as a mechanism for the immune privilege of corneal allografts.

21 January 2018

1 reference

Cytotoxicity of tumor antigen specific human T cells is unimpaired by arginine depletion

21 January 2018

1 reference

Arginase I production in the tumor microenvironment by mature myeloid cells inhibits T-cell receptor expression and antigen-specific T-cell responses

21 January 2018

1 reference

Arginase activity mediates reversible T cell hyporesponsiveness in human pregnancy.

21 January 2018

1 reference

Sterol regulatory element-binding proteins are essential for the metabolic programming of effector T cells and adaptive immunity

21 January 2018

1 reference

Potentiating the antitumour response of CD8(+) T cells by modulating cholesterol metabolism

21 January 2018

1 reference

mTORC1 couples immune signals and metabolic programming to establish T(reg)-cell function

21 January 2018

1 reference

De novo fatty acid synthesis controls the fate between regulatory T and T helper 17 cells.

21 January 2018

1 reference

Normalizing glycosphingolipids restores function in CD4+ T cells from lupus patients.

21 January 2018

1 reference

NAFLD causes selective CD4(+) T lymphocyte loss and promotes hepatocarcinogenesis

21 January 2018

1 reference

The mammalian target of rapamycin: linking T cell differentiation, function, and metabolism

21 January 2018

1 reference

The cytotoxic T cell proteome and its shaping by the kinase mTOR.

21 January 2018

1 reference

Inhibiting glycolytic metabolism enhances CD8+ T cell memory and antitumor function.

21 January 2018

1 reference

Aptamer-targeted inhibition of mTOR in T cells enhances antitumor immunity

21 January 2018

1 reference

Sirolimus Enhances the Magnitude and Quality of Viral-Specific CD8+ T-Cell Responses to Vaccinia Virus Vaccination in Rhesus Macaques

21 January 2018

1 reference

The liver kinase B1 is a central regulator of T cell development, activation, and metabolism

21 January 2018

1 reference

Metformin attenuated the autoimmune disease of the central nervous system in animal models of multiple sclerosis

21 January 2018

1 reference

Novel anti-inflammatory action of 5-aminoimidazole-4-carboxamide ribonucleoside with protective effect in dextran sulfate sodium-induced acute and chronic colitis.

21 January 2018

1 reference

Mitochondria positioning controls local calcium influx in T cells

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27479920