Stabilizing human regulatory T cells for tolerance inducing immunotherapy (Q38644779)

5 September 2017

title

Stabilizing human regulatory T cells for tolerance inducing immunotherapy (English)

1 reference

5 September 2017

1 reference

Xuehui He

0 references

Hans Jpm Koenen

1 reference

5 September 2017

Jeroen Hr Slaats

series ordinal

1 reference

5 September 2017

Irma Joosten

series ordinal

1 reference

5 September 2017

publication date

3 August 2017

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5 September 2017

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X-linked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome is the human equivalent of mouse scurfy

5 September 2017

cites work

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

Type 1 diabetes immunotherapy using polyclonal regulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

Prevalence of newly generated naive regulatory T cells (Treg) is critical for Treg suppressive function and determines Treg dysfunction in multiple sclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

Pathogenic conversion of Foxp3+ T cells into TH17 cells in autoimmune arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

Dysfunctional blood and target tissue CD4+CD25high regulatory T cells in psoriasis: mechanism underlying unrestrained pathogenic effector T cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

Balance of Treg vs. T-helper cells in the transition from symptomless to lesional psoriatic skin.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

Regulatory T cells in systemic lupus erythematosus

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

Regulatory T cells: mechanisms of differentiation and function

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

Human CD4+ regulatory T cells express lower levels of the IL-7 receptor alpha chain (CD127), allowing consistent identification and sorting of live cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

CTLA-4 control over Foxp3+ regulatory T cell function

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

Antigen-specific regulatory T-cell subsets in transplantation tolerance regulatory T-cell subset quality reduces the need for quantity

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

Extracellular adenosine-mediated modulation of regulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

Helios+ and Helios- cells coexist within the natural FOXP3+ T regulatory cell subset in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

Neuropilin-1: a surface marker of regulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

Coexpression of TIGIT and FCRL3 identifies Helios+ human memory regulatory T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

Regulatory T cell identity: formation and maintenance

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

Extrathymically generated regulatory T cells control mucosal TH2 inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

Thymus-derived regulatory T cells contribute to tolerance to commensal microbiota

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

Expression of Helios, an Ikaros transcription factor family member, differentiates thymic-derived from peripherally induced Foxp3+ T regulatory cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

Helios expression is a marker of T cell activation and proliferation.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

Functional delineation and differentiation dynamics of human CD4+ T cells expressing the FoxP3 transcription factor

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

Expansion of human regulatory T-cells from patients with type 1 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

Differential effects of rapamycin and retinoic acid on expansion, stability and suppressive qualities of human CD4(+)CD25(+)FOXP3(+) T regulatory cell subpopulations

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

IL-17-producing human peripheral regulatory T cells retain suppressive function

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

Massive ex vivo expansion of human natural regulatory T cells (T(regs)) with minimal loss of in vivo functional activity

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

Single-Cell Analysis of the Human T Regulatory Population Uncovers Functional Heterogeneity and Instability within FOXP3+ Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

A peripheral circulating compartment of natural naive CD4 Tregs

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

Follicular regulatory T cells expressing Foxp3 and Bcl-6 suppress germinal center reactions

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

Follicular regulatory T cells control humoral autoimmunity via NFAT2-regulated CXCR5 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

IL-21 restricts T follicular regulatory T cell proliferation through Bcl-6 mediated inhibition of responsiveness to IL-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

The transcriptional regulators IRF4, BATF and IL-33 orchestrate development and maintenance of adipose tissue-resident regulatory T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

The alarmin IL-33 promotes regulatory T-cell function in the intestine

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

Induction of Colonic Regulatory T Cells by Indigenous Clostridium Species

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

Memory regulatory T cells reside in human skin

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

Regulation of trafficking receptor expression in human forkhead box P3+ regulatory T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

Administration of CD4+CD25highCD127- regulatory T cells preserves β-cell function in type 1 diabetes in children

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

Tregs prevent GVHD and promote immune reconstitution in HLA-haploidentical transplantation

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

Infusion of ex vivo expanded T regulatory cells in adults transplanted with umbilical cord blood: safety profile and detection kinetics

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

Safety and efficacy of antigen-specific regulatory T-cell therapy for patients with refractory Crohn's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

Rapamycin, and not cyclosporin A, preserves the highly suppressive CD27+ subset of human CD4+CD25+ regulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

Rapamycin selectively expands CD4+CD25+FoxP3+ regulatory T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

Superior T-cell suppression by rapamycin and FK506 over rapamycin and cyclosporine A because of abrogated cytotoxic T-lymphocyte induction, impaired memory responses, and persistent apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

Stability of human rapamycin-expanded CD4+CD25+ T regulatory cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

Targeting PKC in human T cells using sotrastaurin (AEB071) preserves regulatory T cells and prevents IL-17 production.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

De novo generation and enhanced suppression of human CD4+CD25+ regulatory T cells by retinoic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

A TNFR2-Agonist Facilitates High Purity Expansion of Human Low Purity Treg Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

Stability of the regulatory T cell lineage in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

Instability of the transcription factor Foxp3 leads to the generation of pathogenic memory T cells in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

Activation-induced FOXP3 in human T effector cells does not suppress proliferation or cytokine production

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

DNA demethylation in the human FOXP3 locus discriminates regulatory T cells from activated FOXP3(+) conventional T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

Induction of FOXP3 expression in naive human CD4+FOXP3 T cells by T-cell receptor stimulation is transforming growth factor-beta dependent but does not confer a regulatory phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

Loss of FOXP3 expression in natural human CD4+CD25+ regulatory T cells upon repetitive in vitro stimulation

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

Human memory FOXP3+ Tregs secrete IL-17 ex vivo and constitutively express the T(H)17 lineage-specific transcription factor RORgamma t.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

Human CD25highFoxp3pos regulatory T cells differentiate into IL-17-producing cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

Identification of IL-17-producing FOXP3+ regulatory T cells in humans.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

Foxp3+ regulatory T cells, Th17 effector cells, and cytokine environment in inflammatory bowel disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

Epigenetic control of the foxp3 locus in regulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

Role of conserved non-coding DNA elements in the Foxp3 gene in regulatory T-cell fate

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

DNA methylation controls Foxp3 gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

TET enzymes, TDG and the dynamics of DNA demethylation.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

Hydrogen Sulfide Promotes Tet1- and Tet2-Mediated Foxp3 Demethylation to Drive Regulatory T Cell Differentiation and Maintain Immune Homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

Genome-wide scan reveals association of psoriasis with IL-23 and NF-kappaB pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

Lineage-specific DNA methylation in T cells correlates with histone methylation and enhancer activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

Cutting edge: changes in histone acetylation at the IL-4 and IFN-gamma loci accompany Th1/Th2 differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

Deacetylase inhibition promotes the generation and function of regulatory T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

Global mapping of H3K4me3 and H3K27me3 reveals specificity and plasticity in lineage fate determination of differentiating CD4+ T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

The Polycomb complex PRC2 and its mark in life

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

Inflammation-induced repression of chromatin bound by the transcription factor Foxp3 in regulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

The Role of the Histone Methyltransferase Enhancer of Zeste Homolog 2 (EZH2) in the Pathobiological Mechanisms Underlying Inflammatory Bowel Disease (IBD).

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

The chromatin-modifying enzyme Ezh2 is critical for the maintenance of regulatory T cell identity after activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

Development of Foxp3(+) regulatory t cells is driven by the c-Rel enhanceosome

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

c-Rel is required for the development of thymic Foxp3+ CD4 regulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

Nuclear factor-kappaB modulates regulatory T cell development by directly regulating expression of Foxp3 transcription factor.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

Novel Foxo1-dependent transcriptional programs control T(reg) cell function

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

Foxo proteins cooperatively control the differentiation of Foxp3+ regulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

Transcription factors Foxo3a and Foxo1 couple the E3 ligase Cbl-b to the induction of Foxp3 expression in induced regulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

Foxo transcription factors control regulatory T cell development and function

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

Identification of T helper type 1–like, Foxp3+ regulatory T cells in human autoimmune disease

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

Plasticity of human regulatory T cells in healthy subjects and patients with type 1 diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

Smad3 and NFAT cooperate to induce Foxp3 expression through its enhancer

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

Function of a Foxp3 cis-element in protecting regulatory T cell identity

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

Regulating the regulators: costimulatory signals control the homeostasis and function of regulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

Cutting Edge: CD28 Controls Peripheral Homeostasis of CD4+CD25+ Regulatory T Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

Effective proliferation of human regulatory T cells requires a strong costimulatory CD28 signal that cannot be substituted by IL-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

Selective targeting of regulatory T cells with CD28 superagonists allows effective therapy of experimental autoimmune encephalomyelitis

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

Cytokine storm in a phase 1 trial of the anti-CD28 monoclonal antibody TGN1412

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

Monoclonal antibody TGN1412 trial failure explained by species differences in CD28 expression on CD4+ effector memory T-cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

Preculture of PBMCs at high cell density increases sensitivity of T-cell responses, revealing cytokine release by CD28 superagonist TGN1412.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

Human regulatory T cells are selectively activated by low-dose application of the CD28 superagonist TGN1412/TAB08.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

Single CD28 stimulation induces stable and polyclonal expansion of human regulatory T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

The transmembrane form of tumor necrosis factor is the prime activating ligand of the 80 kDa tumor necrosis factor receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

Foxp3 protein stability is regulated by cyclin-dependent kinase 2

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

Phenotype, localization, and mechanism of suppression of CD4(+)CD25(+) human thymocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

Homogeneous expansion of human T-regulatory cells via tumor necrosis factor receptor 2

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

TNF-alpha: an activator of CD4+FoxP3+TNFR2+ regulatory T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

Tolerance, not immunity, crucially depends on IL-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

A low interleukin-2 receptor signaling threshold supports the development and homeostasis of T regulatory cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

Human immune disorder arising from mutation of the alpha chain of the interleukin-2 receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

Immunopathology of interleukin (IL) 2-deficient mice: thymus dependence and suppression by thymus-dependent cells with an intact IL-2 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

Decrease of Foxp3+ Treg cell number and acquisition of effector cell phenotype during lethal infection

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

Regulatory T-cell responses to low-dose interleukin-2 in HCV-induced vasculitis

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

Interleukin-2 and regulatory T cells in graft-versus-host disease

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

Low-dose interleukin-2 selectively corrects regulatory T cell defects in patients with systemic lupus erythematosus

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

Low-dose interleukin 2 in patients with type 1 diabetes: a phase 1/2 randomised, double-blind, placebo-controlled trial

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

Low-dose interleukin-2 fosters a dose-dependent regulatory T cell tuned milieu in T1D patients

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

The promise of low-dose interleukin-2 therapy for autoimmune and inflammatory diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

Heterogeneity of natural Foxp3+ T cells: a committed regulatory T-cell lineage and an uncommitted minor population retaining plasticity

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

TNF downmodulates the function of human CD4+CD25hi T-regulatory cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

Phosphorylation of FOXP3 controls regulatory T cell function and is inhibited by TNF-α in rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

Interaction of TNF with TNF receptor type 2 promotes expansion and function of mouse CD4+CD25+ T regulatory cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

Runx-CBFbeta complexes control expression of the transcription factor Foxp3 in regulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

Indispensable role of the Runx1-Cbfbeta transcription complex for in vivo-suppressive function of FoxP3+ regulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

Methylation matters: binding of Ets-1 to the demethylated Foxp3 gene contributes to the stabilization of Foxp3 expression in regulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

Eos mediates Foxp3-dependent gene silencing in CD4+ regulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

An inherently bifunctional subset of Foxp3+ T helper cells is controlled by the transcription factor eos.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

Prolonged rapamycin treatment inhibits mTORC2 assembly and Akt/PKB

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

The mTOR kinase differentially regulates effector and regulatory T cell lineage commitment

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

Rapamycin promotes expansion of functional CD4+CD25+FOXP3+ regulatory T cells of both healthy subjects and type 1 diabetic patients

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

Differential impact of mammalian target of rapamycin inhibition on CD4+CD25+Foxp3+ regulatory T cells compared with conventional CD4+ T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

Rapamycin monotherapy in patients with type 1 diabetes modifies CD4+CD25+FOXP3+ regulatory T-cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

Immunoregulatory effects of sirolimus vs. tacrolimus treatment in kidney allograft recipients.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

Oscillatory mTOR inhibition and Treg increase in kidney transplantation.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

Impact of immunosuppressive drugs on the therapeutic efficacy of ex vivo expanded human regulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

Retinoid X receptor agonists modulate Foxp3⁺ regulatory T cell and Th17 cell differentiation with differential dependence on retinoic acid receptor activation

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

Critical role of all-trans retinoic acid in stabilizing human natural regulatory T cells under inflammatory conditions

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

Differential requirement of PKC-theta in the development and function of natural regulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

Protein kinase C-theta mediates negative feedback on regulatory T cell function

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

The PKC inhibitor AEB071 may be a therapeutic option for psoriasis.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

Platelet microparticles inhibit IL-17 production by regulatory T cells through P-selectin.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

Treg functional stability and its responsiveness to the microenvironment

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

Regulation of Treg functionality by acetylation-mediated Foxp3 protein stabilization.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

Inhibition of p300 impairs Foxp3⁺ T regulatory cell function and promotes antitumor immunity.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

Stabilization of the transcription factor Foxp3 by the deubiquitinase USP7 increases Treg-cell-suppressive capacity.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

Three novel acetylation sites in the Foxp3 transcription factor regulate the suppressive activity of regulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

TGF-beta and IL-6 signals modulate chromatin binding and promoter occupancy by acetylated FOXP3.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

MicroRNA regulation of lymphocyte tolerance and autoimmunity

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

Foxp3-dependent microRNA155 confers competitive fitness to regulatory T cells by targeting SOCS1 protein

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

Function of miR-146a in controlling Treg cell-mediated regulation of Th1 responses

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

TGF-β and retinoic acid induce the microRNA miR-10a, which targets Bcl-6 and constrains the plasticity of helper T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

microRNA-17-92 regulates IL-10 production by regulatory T cells and control of experimental autoimmune encephalomyelitis.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

Cutting edge: distinct glycolytic and lipid oxidative metabolic programs are essential for effector and regulatory CD4+ T cell subsets.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

Control of PI(3) kinase in Treg cells maintains homeostasis and lineage stability

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

Treg cells require the phosphatase PTEN to restrain TH1 and TFH cell responses.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

Human regulatory T cells with alloantigen specificity are more potent inhibitors of alloimmune skin graft damage than polyclonal regulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

Use of gene-modified regulatory T-cells to control autoimmune and alloimmune pathology: is now the right time?

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

CAR/FoxP3-engineered T regulatory cells target the CNS and suppress EAE upon intranasal delivery.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

Suppression of murine colitis and its associated cancer by carcinoembryonic antigen-specific regulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

Expression of Helios in Peripherally Induced Foxp3+ Regulatory T Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

Neuropilin‐1 is not a marker of human Foxp3+ Treg

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

Altered activation of AKT is required for the suppressive function of human CD4+CD25+ T regulatory cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

Efficient expansion of regulatory T cells in vitro and in vivo with a CD28 superagonist

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

Cutting Edge: TNFR-Shedding by CD4+CD25+ Regulatory T Cells Inhibits the Induction of Inflammatory Mediators

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

Foxp3-dependent programme of regulatory T-cell differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FIMT-2017-0017

21 January 2018

Identifiers

DOI

10.2217/IMT-2017-0017

1 reference

5 September 2017

1 reference