The Role of the Histone Methyltransferase Enhancer of Zeste Homolog 2 (EZH2) in the Pathobiological Mechanisms Underlying Inflammatory Bowel Disease (IBD). (Q46382588)

From Wikidata

Jump to navigation Jump to search

scientific article

Language	Label	Description	Also known as
English	The Role of the Histone Methyltransferase Enhancer of Zeste Homolog 2 (EZH2) in the Pathobiological Mechanisms Underlying Inflammatory Bowel Disease (IBD).	scientific article

Statements

scholarly article

1 reference

Europe PubMed Central

PMC publication ID

6 March 2018

http://europepmc.org/abstract/PMC/5241744

The Role of the Histone Methyltransferase Enhancer of Zeste Homolog 2 (EZH2) in the Pathobiological Mechanisms Underlying Inflammatory Bowel Disease (IBD). (English)

1 reference

Europe PubMed Central

PMC publication ID

6 March 2018

http://europepmc.org/abstract/PMC/5241744

inflammatory bowel diseases

0 references

Thomas C. Smyrk

7

object named as

Thomas C Smyrk

1 reference

Europe PubMed Central

PMC publication ID

6 March 2018

Dermot McGovern

12

object named as

Dermot P B McGovern

1 reference

Europe PubMed Central

PMC publication ID

6 March 2018

http://europepmc.org/abstract/PMC/5241744

Ramnik J Xavier

16

object named as

Ramnik J Xavier

1 reference

Europe PubMed Central

PMC publication ID

6 March 2018

http://europepmc.org/abstract/PMC/5241744

author name string

Olga F Sarmento

1

1 reference

Europe PubMed Central

PMC publication ID

6 March 2018

http://europepmc.org/abstract/PMC/5241744

Phyllis A Svingen

2

1 reference

Europe PubMed Central

PMC publication ID

6 March 2018

http://europepmc.org/abstract/PMC/5241744

Yuning Xiong

3

1 reference

Europe PubMed Central

PMC publication ID

6 March 2018

http://europepmc.org/abstract/PMC/5241744

Zhifu Sun

4

1 reference

Europe PubMed Central

PMC publication ID

6 March 2018

http://europepmc.org/abstract/PMC/5241744

Adebowale O Bamidele

5

1 reference

Europe PubMed Central

PMC publication ID

6 March 2018

http://europepmc.org/abstract/PMC/5241744

Angela J Mathison

6

1 reference

Europe PubMed Central

PMC publication ID

6 March 2018

http://europepmc.org/abstract/PMC/5241744

Asha A Nair

8

1 reference

Europe PubMed Central

PMC publication ID

6 March 2018

http://europepmc.org/abstract/PMC/5241744

Michelle M Gonzalez

9

1 reference

Europe PubMed Central

PMC publication ID

6 March 2018

http://europepmc.org/abstract/PMC/5241744

Mary R Sagstetter

10

1 reference

Europe PubMed Central

PMC publication ID

6 March 2018

http://europepmc.org/abstract/PMC/5241744

Saurabh Baheti

11

1 reference

Europe PubMed Central

PMC publication ID

6 March 2018

http://europepmc.org/abstract/PMC/5241744

Jessica J Friton

13

1 reference

Europe PubMed Central

PMC publication ID

6 March 2018

http://europepmc.org/abstract/PMC/5241744

Konstantinos A Papadakis

14

1 reference

Europe PubMed Central

PMC publication ID

6 March 2018

http://europepmc.org/abstract/PMC/5241744

Goel Gautam

15

1 reference

Europe PubMed Central

PMC publication ID

6 March 2018

http://europepmc.org/abstract/PMC/5241744

Raul A Urrutia

17

1 reference

Europe PubMed Central

PMC publication ID

6 March 2018

http://europepmc.org/abstract/PMC/5241744

William A Faubion

18

1 reference

Europe PubMed Central

PMC publication ID

6 March 2018

http://europepmc.org/abstract/PMC/5241744

language of work or name

0 references

publication date

1 December 2016

1 reference

Europe PubMed Central

PMC publication ID

6 March 2018

http://europepmc.org/abstract/PMC/5241744

Journal of Biological Chemistry

1 reference

Europe PubMed Central

PMC publication ID

6 March 2018

http://europepmc.org/abstract/PMC/5241744

292

1 reference

Europe PubMed Central

PMC publication ID

6 March 2018

http://europepmc.org/abstract/PMC/5241744

2

1 reference

Europe PubMed Central

PMC publication ID

6 March 2018

http://europepmc.org/abstract/PMC/5241744

706-722

1 reference

Europe PubMed Central

PMC publication ID

6 March 2018

http://europepmc.org/abstract/PMC/5241744

Epigenetic modulators, modifiers and mediators in cancer aetiology and progression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5241744

24 May 2018

Graded Foxo1 activity in Treg cells differentiates tumour immunity from spontaneous autoimmunity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5241744

24 May 2018

Myeloproliferative neoplasms: Current molecular biology and genetics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5241744

24 May 2018

EZH2 is crucial for both differentiation of regulatory T cells and T effector cell expansion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5241744

24 May 2018

Targeting EZH2 and PRC2 dependence as novel anticancer therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5241744

24 May 2018

PCAF-primed EZH2 acetylation regulates its stability and promotes lung adenocarcinoma progression.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5241744

24 May 2018

The chromatin-modifying enzyme Ezh2 is critical for the maintenance of regulatory T cell identity after activation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5241744

24 May 2018

HTSeq--a Python framework to work with high-throughput sequencing data

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5241744

24 May 2018

Inflammation-induced repression of chromatin bound by the transcription factor Foxp3 in regulatory T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5241744

24 May 2018

FOXP3 and scurfy: how it all began

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5241744

24 May 2018

Gene expression in the Gitr locus is regulated by NF-κB and Foxp3 through an enhancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5241744

24 May 2018

Noncoding RNAs and LRRFIP1 regulate TNF expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5241744

24 May 2018

O-GlcNAcylation regulates EZH2 protein stability and function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5241744

24 May 2018

Master regulators of FGFR2 signalling and breast cancer risk

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5241744

24 May 2018

Phosphorylation of EZH2 activates STAT3 signaling via STAT3 methylation and promotes tumorigenicity of glioblastoma stem-like cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5241744

24 May 2018

JNK and STAT3 signaling pathways converge on Akt-mediated phosphorylation of EZH2 in bronchial epithelial cells induced by arsenic

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5241744

24 May 2018

Expression of RORγt marks a pathogenic regulatory T cell subset in human colon cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5241744

24 May 2018

Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5241744

24 May 2018

Immune dysregulation, polyendocrinopathy, enteropathy, x-linked syndrome: a paradigm of immunodeficiency with autoimmunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5241744

24 May 2018

Polycomb antagonizes p300/CREB-binding protein-associated factor to silence FOXP3 in a Kruppel-like factor-dependent manner

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5241744

24 May 2018

Dextran sodium sulphate colitis mouse model: traps and tricks

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5241744

24 May 2018

Inner workings and regulatory inputs that control Polycomb repressive complex 2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5241744

24 May 2018

Epigenetic repression of the Igk locus by STAT5-mediated recruitment of the histone methyltransferase Ezh2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5241744

24 May 2018

The Y641C mutation of EZH2 alters substrate specificity for histone H3 lysine 27 methylation states

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5241744

24 May 2018

Cyclin-dependent Kinase 1 (CDK1)-mediated Phosphorylation of Enhancer of Zeste 2 (Ezh2) Regulates Its Stability

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5241744

24 May 2018

Somatic mutations at EZH2 Y641 act dominantly through a mechanism of selectively altered PRC2 catalytic activity, to increase H3K27 trimethylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5241744

24 May 2018

Characterization of Interleukin-17–Producing Regulatory T Cells in Inflamed Intestinal Mucosa From Patients With Inflammatory Bowel Diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5241744

24 May 2018

The pathogen recognition receptor NOD2 regulates human FOXP3+ T cell survival.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5241744

24 May 2018

Differentiation of effector CD4 T cell populations (*)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5241744

24 May 2018

FoxP3+RORgammat+ T helper intermediates display suppressive function against autoimmune diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5241744

24 May 2018

The transcriptional network for mesenchymal transformation of brain tumours.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5241744

24 May 2018

edgeR: a Bioconductor package for differential expression analysis of digital gene expression data

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5241744

24 May 2018

Smad3 differentially regulates the induction of regulatory and inflammatory T cell differentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5241744

24 May 2018

Epigenetic mechanisms of regulation of Foxp3 expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5241744

24 May 2018

DZNep is a global histone methylation inhibitor that reactivates developmental genes not silenced by DNA methylation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5241744

24 May 2018

TopHat: discovering splice junctions with RNA-Seq

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5241744

24 May 2018

TFCat: the curated catalog of mouse and human transcription factors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5241744

24 May 2018

Identification of IL-17-producing FOXP3+ regulatory T cells in humans.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5241744

24 May 2018

Ultrafast and memory-efficient alignment of short DNA sequences to the human genome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5241744

24 May 2018

Genomic loss of microRNA-101 leads to overexpression of histone methyltransferase EZH2 in cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5241744

24 May 2018

Mapping and quantifying mammalian transcriptomes by RNA-Seq

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5241744

24 May 2018

Pharmacologic disruption of Polycomb-repressive complex 2-mediated gene repression selectively induces apoptosis in cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5241744

24 May 2018

The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5241744

24 May 2018

Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5241744

24 May 2018

Scurfin (FOXP3) acts as a repressor of transcription and regulates T cell activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5241744

24 May 2018

X-linked lymphoreticular disease in the scurfy (sf) mutant mouse

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5241744

24 May 2018

Oncogenic Y641 mutations in EZH2 prevent Jak2/β-TrCP-mediated degradation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5241744

15 August 2018

The polycomb protein Ezh2 regulates differentiation and plasticity of CD4(+) T helper type 1 and type 2 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5241744

15 August 2018

Increased prevalence of circulating novel IL-17 secreting Foxp3 expressing CD4+ T cells and defective suppressive function of circulating Foxp3+ regulatory cells support plasticity between Th17 and regulatory T cells in inflammatory bowel disease pa

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5241744

15 August 2018

Profiling of human CD4+ T-cell subsets identifies the TH2-specific noncoding RNA GATA3-AS1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5241744

15 August 2018

Pretreatment with interferon-γ enhances the therapeutic activity of mesenchymal stromal cells in animal models of colitis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5241744

15 August 2018

Polycomb group protein ezh2 controls actin polymerization and cell signaling.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5241744

15 August 2018

Colitis is associated with thymic destruction attenuating CD4+25+ regulatory T cells in the periphery

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5241744

15 August 2018

The polycomb repressive complex 2 governs life and death of peripheral T cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M116.749663

21 January 2018

Activating mutations of the oncogene EZH2 in cutaneous melanoma revealed by next generation sequencing

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M116.749663

21 January 2018

Foxp3-dependent programme of regulatory T-cell differentiation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M116.749663

21 January 2018

Glycolysis and EZH2 boost T cell weaponry against tumors

1 reference

https://pubmed.ncbi.nlm.nih.gov/27909059

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Unconventional association of the polycomb group proteins with cytokine genes in differentiated T helper cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/27909059

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Autoimmune polyglandular syndromes

1 reference

https://pubmed.ncbi.nlm.nih.gov/27909059

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ICOS-dependent homeostasis and function of Foxp3+ regulatory T cells in islets of nonobese diabetic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/27909059

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M116.749663

1 reference

Europe PubMed Central

PMC publication ID

6 March 2018

http://europepmc.org/abstract/PMC/5241744

release_32xegizasfccziozb56z3733ju

1 reference

https://api.fatcat.wiki/v0/release/32xegizasfccziozb56z3733ju

24 November 2022

based on heuristic

mapped directly with Wikidata item

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

6 March 2018

http://europepmc.org/abstract/PMC/5241744

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

6 March 2018

http://europepmc.org/abstract/PMC/5241744

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q46382588&oldid=1837797654"