Senescence suppressors: their practical importance in replicative lifespan extension in stem cells (Q38232804)

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

Growth kinetics, self-renewal, and the osteogenic potential of purified human mesenchymal stem cells during extensive subcultivation and following cryopreservation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

Aging is associated with decreased maximal life span and accelerated senescence of bone marrow stromal cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

Propagation and senescence of human marrow stromal cells in culture: a simple colony-forming assay identifies samples with the greatest potential to propagate and differentiate

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

Aging of mesenchymal stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

Aging effect on neurotrophic activity of human mesenchymal stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

Human adipose-derived mesenchymal stem cells: serial passaging, doubling time and cell senescence

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

Cartilage Matrix Formation by Bovine Mesenchymal Stem Cells in Three-dimensional Culture Is Age-dependent

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

Increasing p16INK4a expression decreases forebrain progenitors and neurogenesis during ageing

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

Replicative senescence and senescence-like state induced in cancer-derived cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

The switch from pRb/p105 to Rb2/p130 in DNA damage and cellular senescence

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

Silencing of RB1 but not of RB2/P130 induces cellular senescence and impairs the differentiation potential of human mesenchymal stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

The Effect of Low Oxygen Tension on the in Vitro-Replicative Life Span of Human Diploid Fibroblast Cells and Their Transformed Derivatives

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

Culture of human mesenchymal stem cells at low oxygen tension improves growth and genetic stability by activating glycolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

Cell survival responses to environmental stresses via the Keap1-Nrf2-ARE pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

Nuclear erythroid factor 2-mediated proteasome activation delays senescence in human fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

Antioxidants Enhance Mammalian Proteasome Expression through the Keap1-Nrf2 Signaling Pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

Stabilization of Nrf2 by tBHQ confers protection against oxidative stress-induced cell death in human neural stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

Redox regulation of stem and progenitor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

Potential role of 20S proteasome in maintaining stem cell integrity of human bone marrow stromal cells in prolonged culture expansion

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

Oxidative stress and aberrant signaling in aging and cognitive decline

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

SOD1 and DJ-1 converge at Nrf2 pathway: a clue for antioxidant therapeutic potential in neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

Potential therapeutic effects of natural heme oxygenase-1 inducers in cardiovascular diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

Degradation of oxidized proteins by the 20S proteasome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

Proteasome inhibitors induce intracellular protein aggregation and cell death by an oxygen-dependent mechanism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

Selective degradation of oxidatively modified protein substrates by the proteasome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

The ubiquitin proteasome system in neuropathology

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

Central role of the proteasome in senescence and survival of human fibroblasts: induction of a senescence-like phenotype upon its inhibition and resistance to stress upon its activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

Proteasome inhibition induces a senescence-like phenotype in primary human fibroblasts cultures

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

Crosstalk between Nrf2 and the proteasome: therapeutic potential of Nrf2 inducers in vascular disease and aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

Sirtuins--novel therapeutic targets to treat age-associated diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

Do sirtuins promote mammalian longevity? A critical review on its relevance to the longevity effect induced by calorie restriction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

miRNAs regulate SIRT1 expression during mouse embryonic stem cell differentiation and in adult mouse tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

Progressive loss of SIRT1 with cell cycle withdrawal

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

SIRT1 overexpression antagonizes cellular senescence with activated ERK/S6k1 signaling in human diploid fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

SirT1--a sensor for monitoring self-renewal and aging process in retinal stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

Human SIR2 deacetylates p53 and antagonizes PML/p53-induced cellular senescence

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

SIRT1 regulates apoptosis and Nanog expression in mouse embryonic stem cells by controlling p53 subcellular localization

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

Negative control of p53 by Sir2alpha promotes cell survival under stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

Sirt1 modulates premature senescence-like phenotype in human endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

The c-MYC oncoprotein, the NAMPT enzyme, the SIRT1-inhibitor DBC1, and the SIRT1 deacetylase form a positive feedback loop

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

SIRT1 contributes to telomere maintenance and augments global homologous recombination

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

SIRT1 prevents replicative senescence of normal human umbilical cord fibroblast through potentiating the transcription of human telomerase reverse transcriptase gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

SirT1 regulation of antioxidant genes is dependent on the formation of a FoxO3a/PGC-1α complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

SIRT1 protects against cigarette smoke-induced lung oxidative stress via a FOXO3-dependent mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

A role for the NAD-dependent deacetylase Sirt1 in the regulation of autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

Calorie restriction enhances cell adaptation to hypoxia through Sirt1-dependent mitochondrial autophagy in mouse aged kidney

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

Mammalian SIRT1 limits replicative life span in response to chronic genotoxic stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

Ubiquitin-independent degradation of cell-cycle inhibitors by the REGgamma proteasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

p53 induces differentiation of mouse embryonic stem cells by suppressing Nanog expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

Lineage-specific regulation of the neural differentiation gene MASH1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

Sirt1 contributes critically to the redox-dependent fate of neural progenitors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

Neurogenesis directed by Sirt1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

RETRACTED: Visfatin: a protein secreted by visceral fat that mimics the effects of insulin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

Inhibition of silencing and accelerated aging by nicotinamide, a putative negative regulator of yeast sir2 and human SIRT1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

Increased nuclear NAD biosynthesis and SIRT1 activation prevent axonal degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

Nicotinamide enhances mitochondria quality through autophagy activation in human cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

Nicotinamide-induced mitophagy: event mediated by high NAD+/NADH ratio and SIRT1 protein activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

Role of sirtuins in lifespan regulation is linked to methylation of nicotinamide

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

Nicotinamide (vitamin B3) as an effective antioxidant against oxidative damage in rat brain mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

Mutation of the mouse klotho gene leads to a syndrome resembling ageing

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

Regulation of fibroblast growth factor-23 signaling by klotho

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

Klotho converts canonical FGF receptor into a specific receptor for FGF23

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

Klotho suppresses RIG-I-mediated senescence-associated inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

Oncogene-induced senescence relayed by an interleukin-dependent inflammatory network

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

Klotho RNAi induces premature senescence of human cells via a p53/p21 dependent pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

Heme oxygenase and heme degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

Heme Oxygenase-1 Couples Activation of Mitochondrial Biogenesis to Anti-inflammatory Cytokine Expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

Haem oxygenase-1 regulates catabolic and anabolic processes in osteoarthritic chondrocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

Haem oxygenase-1 down-regulates high mobility group box 1 and matrix metalloproteinases in osteoarthritic synoviocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

Overexpression of heme oxygenase-1 increases human osteoblast stem cell differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

Heme oxygenase-1 mediates protective effects on inflammatory, catabolic and senescence responses induced by interleukin-1β in osteoarthritic osteoblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

Biliverdin reductase: a major physiologic cytoprotectant

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

Biliverdin reductase is a transporter of haem into the nucleus and is essential for regulation of HO-1 gene expression by haematin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

Heme oxygenase-1 posttranslational modifications in the brain of subjects with Alzheimer disease and mild cognitive impairment

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

Biliverdin reductase A in the prevention of cellular senescence against oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

Transcriptional Regulation of the Heme Oxygenase-1 Gene Via the Stress Response Element Pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

PPARalpha activator effects on Ang II-induced vascular oxidative stress and inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

Antioxidative, Antinitrative, and Vasculoprotective Effects of a Peroxisome Proliferator–Activated Receptor-γ Agonist in Hypercholesterolemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

Klotho is a target gene of PPAR-gamma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

PPARs and molecular mechanisms of transrepression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

Complete rescue of cerebrovascular function in aged Alzheimer's disease transgenic mice by antioxidants and pioglitazone, a peroxisome proliferator-activated receptor gamma agonist

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

Azelaic acid reduced senescence-like phenotype in photo-irradiated human dermal fibroblasts: possible implication of PPARγ.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

PPARγ activation by baicalin suppresses NF-κB-mediated inflammation in aged rat kidney

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

PPARδ coordinates angiotensin II-induced senescence in vascular smooth muscle cells through PTEN-mediated inhibition of superoxide generation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

The PPARgamma agonist pioglitazone ameliorates aging-related progressive renal injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

Activation of nuclear factor erythroid 2-related factor 2 and PPARγ plays a role in the genistein-mediated attenuation of oxidative stress-induced endothelial cell injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

Nrf2-regulated PPAR{gamma} expression is critical to protection against acute lung injury in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

Prion protein (PrPc) positively regulates neural precursor proliferation during developmental and adult mammalian neurogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

Prion disease: a deadly disease for protein misfolding.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

A small molecule modulator of prion protein increases human mesenchymal stem cell lifespan, ex vivo expansion, and engraftment to bone marrow in NOD/SCID mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

Prion protein expression and superoxide dismutase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

Normal prion protein has an activity like that of superoxide dismutase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

The octarepeat region of prion protein, but not the TM1 domain, is important for the antioxidant effect of prion protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

Expression of prion protein increases cellular copper binding and antioxidant enzyme activities but not copper delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

Design, synthesis, and structure-activity relationship of indole-3-glyoxylamide libraries possessing highly potent activity in a cell line model of prion disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

Circulating endothelial progenitor cells, vascular function, and cardiovascular risk

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

HMG-CoA reductase inhibitor mobilizes bone marrow--derived endothelial progenitor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

The HMG-CoA reductase inhibitor simvastatin activates the protein kinase Akt and promotes angiogenesis in normocholesterolemic animals

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

HMG-CoA reductase inhibitors reduce senescence and increase proliferation of endothelial progenitor cells via regulation of cell cycle regulatory genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

Pro-atherogenic factors induce telomerase inactivation in endothelial cells through an Akt-dependent mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

HMG-CoA reductase inhibitors (statins) increase endothelial progenitor cells via the PI 3-kinase/Akt pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

Reciprocal control of Forkhead box O 3a and c-Myc via the phosphatidylinositol 3-kinase pathway coordinately regulates p27Kip1 levels.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

HMG-CoA reductase inhibitors improve endothelial dysfunction in normocholesterolemic hypertension via reduced production of reactive oxygen species

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

Cellular antioxidant effects of atorvastatin in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

Induction of endothelial nitric oxide synthase, SIRT1, and catalase by statins inhibits endothelial senescence through the Akt pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

Modulation of PPAR in aging, inflammation, and calorie restriction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

Simvastatin rises reactive oxygen species levels and induces senescence in human melanoma cells by activation of p53/p21 pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

Improved proliferation and differentiation capacity of human mesenchymal stromal cells cultured with basement-membrane extracellular matrix proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

Reconstitution of marrow-derived extracellular matrix ex vivo: a robust culture system for expanding large-scale highly functional human mesenchymal stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

Vascular endothelial cell senescence mediated by integrin beta4 in vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

Modulation of vascular endothelial cell senescence by integrin β4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

Rescuing replication and osteogenesis of aged mesenchymal stem cells by exposure to a young extracellular matrix

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

The effects of calcium phosphate cement particles on osteoblast functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

Chromatin remodelling in mammalian differentiation: lessons from ATP-dependent remodellers

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

The BRG1 ATPase of chromatin remodeling complexes is involved in modulation of mesenchymal stem cell senescence through RB-P53 pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

Nutrient availability regulates SIRT1 through a forkhead-dependent pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

Transactivation of miR-34a by p53 broadly influences gene expression and promotes apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

miR-519 reduces cell proliferation by lowering RNA-binding protein HuR levels

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

Phosphorylation of HuR by Chk2 regulates SIRT1 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

Cathepsin cleavage of sirtuin 1 in endothelial progenitor cells mediates stress-induced premature senescence

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

SIRT1 is a redox-sensitive deacetylase that is post-translationally modified by oxidants and carbonyl stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

Bmi-1 determines the proliferative capacity of normal and leukaemic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

Bmi-1 promotes neural stem cell self-renewal and neural development but not mouse growth and survival by repressing the p16Ink4a and p19Arf senescence pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

The oncogene and Polycomb-group gene bmi-1 regulates cell proliferation and senescence through the ink4a locus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

Control of the replicative life span of human fibroblasts by p16 and the polycomb protein Bmi-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

Bmi-1 regulates self-renewal, proliferation and senescence of human fetal neural stem cells in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

Bmi-1 over-expression in neural stem/progenitor cells increases proliferation and neurogenesis in culture but has little effect on these functions in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

Successful immortalization of mesenchymal progenitor cells derived from human placenta and the differentiation abilities of immortalized cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

Multiple docking sites on substrate proteins form a modular system that mediates recognition by ERK MAP kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

Bmi-1, stem cells and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

Amplification of PPM1D in human tumors abrogates p53 tumor-suppressor activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

Inactivation of the Wip1 phosphatase inhibits mammary tumorigenesis through p38 MAPK-mediated activation of the p16(Ink4a)-p19(Arf) pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

Senescent growth arrest in mesenchymal stem cells is bypassed by Wip1-mediated downregulation of intrinsic stress signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

The modulation of the oxidative stress response in chondrocytes by Wip1 and its effect on senescence and dedifferentiation during in vitro expansion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

Stems cells and the pathways to aging and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

Oxygen sensitivity severely limits the replicative lifespan of murine fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

The redox regulation of thiol dependent signaling pathways in cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

Telomerase expression extends the proliferative life-span and maintains the osteogenic potential of human bone marrow stromal cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

Maintenance of differentiation potential of human bone marrow mesenchymal stem cells immortalized by human telomerase reverse transcriptase gene despite [corrected] extensive proliferation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

Differentiation of human umbilical cord mesenchymal stem cells into hepatocyte-like cells by hTERT gene transfection in vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

Testing the "garbage" accumulation theory of ageing: mitotic activity protects cells from death induced by inhibition of autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

Autophagy as an essential cellular antioxidant pathway in neurodegenerative disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

Small molecule SIRT1 activators for the treatment of aging and age-related diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

SRT1720, SRT2183, SRT1460, and resveratrol are not direct activators of SIRT1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

BG-12 (dimethyl fumarate): a review of mechanism of action, efficacy, and safety

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

Decline in transcriptional activity of Nrf2 causes age-related loss of glutathione synthesis, which is reversible with lipoic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

Sulforaphane and alpha-lipoic acid upregulate the expression of the pi class of glutathione S-transferase through c-jun and Nrf2 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

Sulforaphane enhances the activity of the Nrf2-ARE pathway and attenuates inflammation in OxyHb-induced rat vascular smooth muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

Extremely potent triterpenoid inducers of the phase 2 response: correlations of protection against oxidant and inflammatory stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

Characterization of heme oxygenase 1 (heat shock protein 32) induction by atrial natriuretic peptide in human endothelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

Low oxygen concentration extends the lifespan of cultured human diploid cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1685-1

Transcriptional up-regulation of antioxidant genes by PPARδ inhibits angiotensin II-induced premature senescence in vascular smooth muscle cells

21 January 2018

1 reference

12 December 2020

Ligand-activated PPARδ inhibits UVB-induced senescence of human keratinocytes via PTEN-mediated inhibition of superoxide production

1 reference

12 December 2020

SIRT1 is required for long-term growth of human mesenchymal stem cells.

1 reference

12 December 2020

Prion protein binds copper within the physiological concentration range

1 reference

12 December 2020

SIRT1 markedly extends replicative lifespan if the NAD+ salvage pathway is enhanced

1 reference

12 December 2020

The PPARδ-mediated inhibition of angiotensin II-induced premature senescence in human endothelial cells is SIRT1-dependent

1 reference

12 December 2020

Age-associated decrease in proteasome content and activities in human dermal fibroblasts: restoration of normal level of proteasome subunits reduces aging markers in fibroblasts from elderly persons

1 reference

12 December 2020

Extension of human cell lifespan by nicotinamide phosphoribosyltransferase

1 reference

12 December 2020

Comparative effects of pitavastatin and probucol on oxidative stress, Cu/Zn superoxide dismutase, PPAR-gamma, and aortic stiffness in hypercholesterolemia

1 reference

12 December 2020

Therapeutic potential of ex vivo expanded endothelial progenitor cells for myocardial ischemia

1 reference

12 December 2020

Bmi-1 collaborates with c-Myc in tumorigenesis by inhibiting c-Myc-induced apoptosis via INK4a/ARF.

1 reference

12 December 2020

Replicative senescence of human fibroblasts: the role of Ras-dependent signaling and oxidative stress

1 reference

12 December 2020

Stem-cell ageing modified by the cyclin-dependent kinase inhibitor p16INK4a

1 reference

12 December 2020

Transforming growth factor-beta1 is a molecular target for the peroxisome proliferator-activated receptor delta

1 reference

12 December 2020

Human bone marrow stromal cells express a distinct set of biologically functional chemokine receptors

1 reference

12 December 2020

MicroRNA Regulation of SIRT1.

1 reference

12 December 2020

A perspective on dietary phytochemicals and cancer chemoprevention: oxidative stress, nrf2, and epigenomics

1 reference

12 December 2020

The Bmi-1 oncogene induces telomerase activity and immortalizes human mammary epithelial cells

1 reference

12 December 2020

Homocysteine accelerates senescence and reduces proliferation of endothelial progenitor cells

1 reference

12 December 2020

Mesenchymal Stem Cells for Treatment of Therapy-Resistant Graft-versus-Host Disease

1 reference

12 December 2020

Physiological antioxidative network of the bilirubin system in aging and age-related diseases

1 reference

12 December 2020

Genetic and functional changes in mitochondria associated with aging

1 reference

12 December 2020

Proteasome inhibitors: a novel class of potent and effective antitumor agents.

1 reference

12 December 2020

The nuclear oncoproteins: RB and p53.

1 reference

12 December 2020

A number of bone marrow mesenchymal stem cells but neither phenotype nor differentiation capacities changes with age of rats

1 reference

12 December 2020

Rosiglitazone increases cerebral klotho expression to reverse baroreflex in type 1-like diabetic rats

1 reference

12 December 2020

Restoration of senescent human diploid fibroblasts by modulation of the extracellular matrix

1 reference

12 December 2020

Primary murine MSC show highly efficient homing to the bone marrow but lose homing ability following culture

1 reference

12 December 2020

E2F1: a potential negative regulator of hTERT transcription in normal cells upon activation of oncogenic c-Myc

1 reference

12 December 2020

1 reference

12 December 2020