Targeted genome regulation and modification using transcription activator-like effectors (Q38239949)

31 August 2017

title

Targeted genome regulation and modification using transcription activator-like effectors (English)

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31 August 2017

James N F Scott

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31 August 2017

Adam P Kupinski

series ordinal

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31 August 2017

Joan Boyes

series ordinal

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31 August 2017

language of work or name

English

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publication date

6 September 2014

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31 August 2017

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31 August 2017

volume

281

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31 August 2017

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31 August 2017

page(s)

4583-4597

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Xanthomonas AvrBs3 family-type III effectors: discovery and function

31 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12973

Characterization and DNA-binding specificities of Ralstonia TAL-like effectors

21 January 2018

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Breaking the DNA-binding code of Ralstonia solanacearum TAL effectors provides new possibilities to generate plant resistance genes against bacterial wilt disease

21 January 2018

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https://api.crossref.org/works/10.1111%2FFEBS.12973

Plant pathogen recognition mediated by promoter activation of the pepper Bs3 resistance gene

21 January 2018

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https://api.crossref.org/works/10.1111%2FFEBS.12973

A bacterial effector acts as a plant transcription factor and induces a cell size regulator

21 January 2018

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https://api.crossref.org/works/10.1111%2FFEBS.12973

Genetic and structural characterization of the avirulence gene avrBs3 from Xanthomonas campestris pv. vesicatoria

21 January 2018

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https://api.crossref.org/works/10.1111%2FFEBS.12973

Breaking the code of DNA binding specificity of TAL-type III effectors

21 January 2018

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https://api.crossref.org/works/10.1111%2FFEBS.12973

A simple cipher governs DNA recognition by TAL effectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12973

Comprehensive interrogation of natural TALE DNA-binding modules and transcriptional repressor domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12973

A TALE nuclease architecture for efficient genome editing

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12973

Quantitative analysis of TALE-DNA interactions suggests polarity effects.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12973

Targeting G with TAL effectors: a comparison of activities of TALENs constructed with NN and NK repeat variable di-residues

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12973

The Crystal Structure of TAL Effector PthXo1 Bound to Its DNA Target

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12973

Structural Basis for Sequence-Specific Recognition of DNA by TAL Effectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12973

A transcription activator-like effector toolbox for genome engineering

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12973

Crystal structure of a TALE protein reveals an extended N-terminal DNA binding region

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12973

Directed evolution of the TALE N-terminal domain for recognition of all 5' bases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12973

Creating a TALE protein with unbiased 5'-T binding.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12973

Broad specificity profiling of TALENs results in engineered nucleases with improved DNA-cleavage specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12973

Efficient design and assembly of custom TALEN and other TAL effector-based constructs for DNA targeting

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12973

A TALEN genome-editing system for generating human stem cell-based disease models

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12973

Rapid and highly efficient construction of TALE-based transcriptional regulators and nucleases for genome modification

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12973

FLASH assembly of TALENs for high-throughput genome editing

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12973

Rapid hierarchical assembly of medium-size DNA cassettes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12973

A ligation-independent cloning technique for high-throughput assembly of transcription activator–like effector genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12973

Efficient construction of sequence-specific TAL effectors for modulating mammalian transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12973

A library of TAL effector nucleases spanning the human genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12973

Type III-dependent translocation of the Xanthomonas AvrBs3 protein into the plant cell.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12973

TAL Effector-Nucleotide Targeter (TALE-NT) 2.0: tools for TAL effector design and target prediction

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12973

Mojo Hand, a TALEN design tool for genome editing applications.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12973

E-TALEN: a web tool to design TALENs for genome engineering.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12973

SAPTA: a new design tool for improving TALE nuclease activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12973

TALENs: a widely applicable technology for targeted genome editing

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12973

Genetic engineering of human pluripotent cells using TALE nucleases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12973

Targeted gene disruption in somatic zebrafish cells using engineered TALENs

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12973

In vivo genome editing using a high-efficiency TALEN system

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12973

Heritable gene targeting in zebrafish using customized TALENs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12973

Production of Sry knockout mouse using TALEN via oocyte injection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12973

Knockout rats generated by embryo microinjection of TALENs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12973

Transcription activator-like effector nucleases enable efficient plant genome engineering.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12973

TALEN utilization in rice genome modifications.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12973

Efficient and specific modifications of the Drosophila genome by means of an easy TALEN strategy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12973

Overview: generation of gene knockout mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12973

Translating human genetics into mouse: the impact of ultra-rapid in vivo genome editing

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12973

Simultaneous gene editing by injection of mRNAs encoding transcription activator-like effector nucleases into mouse zygotes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12973

Targeted gene addition into a specified location in the human genome using designed zinc finger nucleases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12973

Transcription activator-like effector nuclease-mediated transduction of exogenous gene into IL2RG locus

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12973

TALENs facilitate targeted genome editing in human cells with high specificity and low cytotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12973

Enhancing zinc-finger-nuclease activity with improved obligate heterodimeric architectures

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12973

Directed evolution of an enhanced and highly efficient FokI cleavage domain for zinc finger nucleases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12973

An improved zinc-finger nuclease architecture for highly specific genome editing

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12973

Compact designer TALENs for efficient genome engineering

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12973

GAL4-VP16 is an unusually potent transcriptional activator

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12973

Transcription activator-like effector hybrids for conditional control and rewiring of chromosomal transgene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12973

Mad proteins contain a dominant transcription repression domain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12973

Krüppel-associated boxes are potent transcriptional repression domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12973

TALE activators regulate gene expression in a position- and strand-dependent manner in mammalian cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12973

An efficient antiviral strategy for targeting hepatitis B virus genome using transcription activator-like effector nucleases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12973

Visualization of repetitive DNA sequences in human chromosomes with transcription activator-like effectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12973

Robust, synergistic regulation of human gene expression using TALE activators

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12973

Synergistic and tunable human gene activation by combinations of synthetic transcription factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12973

TALE proteins bind to both active and inactive chromatin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12973

Recognition of methylated DNA by TAL effectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12973

Overcoming transcription activator-like effector (TALE) DNA binding domain sensitivity to cytosine methylation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12973

Targeted transcriptional activation of silent oct4 pluripotency gene by combining designer TALEs and inhibition of epigenetic modifiers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12973

Targeted DNA demethylation and activation of endogenous genes using programmable TALE-TET1 fusion proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12973

Enhancing Gene Targeting with Designed Zinc Finger Nucleases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12973

Genome editing with engineered zinc finger nucleases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12973

Zinc finger-DNA recognition: crystal structure of a Zif268-DNA complex at 2.1 A

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12973

Genome Engineering With Zinc-Finger Nucleases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12973

Engineering zinc finger protein transcription factors: the therapeutic relevance of switching endogenous gene expression on or off at command

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12973

Gene editing of CCR5 in autologous CD4 T cells of persons infected with HIV

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12973

The zinc finger nuclease monopoly.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12973

De novo-engineered transcription activator-like effector (TALE) hybrid nuclease with novel DNA binding specificity creates double-strand breaks

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12973

Improved somatic mutagenesis in zebrafish using transcription activator-like effector nucleases (TALENs).

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12973

Cas9 as a versatile tool for engineering biology

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12973

Genome engineering using the CRISPR-Cas9 system

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12973

Cas9-based tools for targeted genome editing and transcriptional control.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12973

One-step generation of mice carrying reporter and conditional alleles by CRISPR/Cas-mediated genome engineering

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12973

Generation of gene-modified cynomolgus monkey via Cas9/RNA-mediated gene targeting in one-cell embryos.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12973

Dynamic imaging of genomic loci in living human cells by an optimized CRISPR/Cas system

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12973

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12973

21 January 2018

Identifiers

DOI

10.1111/FEBS.12973

1 reference

31 August 2017

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