Mad proteins contain a dominant transcription repression domain. (Q40020073)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8816491%20AND%20SRC:MED&resulttype=core&format=json

19 October 2019

title

Mad proteins contain a dominant transcription repression domain (English)

1 reference

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19 October 2019

1 reference

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19 October 2019

C D Laherty

1 reference

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19 October 2019

Q A Lawrence

series ordinal

1 reference

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19 October 2019

A P Armstrong

series ordinal

1 reference

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19 October 2019

R N Eisenman

series ordinal

1 reference

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19 October 2019

language of work or name

English

0 references

publication date

1 October 1996

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8816491%20AND%20SRC:MED&resulttype=core&format=json

Molecular and Cellular Biology

19 October 2019

published in

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19 October 2019

volume

1 reference

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19 October 2019

issue

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19 October 2019

page(s)

5772-5781

1 reference

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SIN3-dependent transcriptional repression by interaction with the Mad1 DNA-binding protein

19 October 2019

cites work

1 reference

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Mouse Sin3A interacts with and can functionally substitute for the amino-terminal repression of the Myc antagonist Mxi1

22 September 2017

1 reference

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Inhibition of cell proliferation by the Mad1 transcriptional repressor

22 September 2017

1 reference

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A mammalian histone deacetylase related to the yeast transcriptional regulator Rpd3p

22 September 2017

1 reference

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Unliganded thyroid hormone receptor alpha can target TATA-binding protein for transcriptional repression

22 September 2017

1 reference

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SSN genes that affect transcriptional repression in Saccharomyces cerevisiae encode SIN4, ROX3, and SRB proteins associated with RNA polymerase II

22 September 2017

1 reference

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Mad3 and Mad4: novel Max-interacting transcriptional repressors that suppress c-myc dependent transformation and are expressed during neural and epidermal differentiation

22 September 2017

1 reference

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Transcriptional repression in Saccharomyces cerevisiae by a SIN3-LexA fusion protein

22 September 2017

1 reference

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Mxi1, a protein that specifically interacts with Max to bind Myc-Max recognition sites

22 September 2017

1 reference

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Mad: a heterodimeric partner for Max that antagonizes Myc transcriptional activity

22 September 2017

1 reference

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Opposite regulation of gene transcription and cell proliferation by c-Myc and Max.

22 September 2017

1 reference

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The ornithine decarboxylase gene is a transcriptional target of c-Myc

22 September 2017

1 reference

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Mammalian Ras interacts directly with the serine/threonine kinase Raf

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231578

A multisubunit complex associated with the RNA polymerase II CTD and TATA-binding protein in yeast.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231578

Suppression of Myc, but not E1a, transformation activity by Max-associated proteins, Mad and Mxi1

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231578

Repression of cyclin D1: a novel function of MYC

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231578

An E-box element localized in the first intron mediates regulation of the prothymosin alpha gene by c-myc

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231578

An RNA polymerase II holoenzyme responsive to activators

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231578

Transcriptional repression by the human bZIP factor E4BP4: definition of a minimal repression domain

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231578

c-Myc represses transcription in vivo by a novel mechanism dependent on the initiator element and Myc box II

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231578

Facilitated binding of TATA-binding protein to nucleosomal DNA

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231578

Nucleosome disruption and enhancement of activator binding by a human SW1/SNF complex

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231578

Stimulation of GAL4 derivative binding to nucleosomal DNA by the yeast SWI/SNF complex

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231578

Epistasis analysis of suppressor mutations that allow HO expression in the absence of the yeast SW15 transcriptional activator

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231578

Groucho is required for Drosophila neurogenesis, segmentation, and sex determination and interacts directly with hairy-related bHLH proteins

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231578

Structure-function analysis of the TBP-binding protein Dr1 reveals a mechanism for repression of class II gene transcription

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231578

The SNF/SWI family of global transcriptional activators

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231578

Expression of the mad gene during cell differentiation in vivo and its inhibition of cell growth in vitro

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231578

An amino-terminal domain of Mxi1 mediates anti-Myc oncogenic activity and interacts with a homolog of the yeast transcriptional repressor SIN3

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231578

Mad-Max transcriptional repression is mediated by ternary complex formation with mammalian homologs of yeast repressor Sin3

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231578

Repression of activator-mediated transcription by herpes simplex virus ICP4 via a mechanism involving interactions with the basal transcription factors TATA-binding protein and TFIIB.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231578

Mutation of the MXI1 gene in prostate cancer

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231578

Repression by SSN6-TUP1 is directed by MIG1, a repressor/activator protein

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231578

Contrasting roles for Myc and Mad proteins in cellular growth and differentiation

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231578

The Transcriptional Repressor Even-skipped Interacts Directly with TATA-Binding Protein

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231578

Differential effects by Mad and Max on transformation by cellular and viral oncoproteins

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231578

Transcriptional Regulation: Flipping the Myc switch

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231578

A transcriptional co-repressor that interacts with nuclear hormone receptors

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231578

Ligand-independent repression by the thyroid hormone receptor mediated by a nuclear receptor co-repressor

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231578

Yeast global transcriptional regulators Sin4 and Rgr1 are components of mediator complex/RNA polymerase II holoenzyme.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231578

Definition of regions in human c-myc that are involved in transformation and nuclear localization

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231578

Analysis of Sp1 in vivo reveals multiple transcriptional domains, including a novel glutamine-rich activation motif

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231578

Activation of transcription by two factors that bind promoter and enhancer sequences of the human metallothionein gene and SV40

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231578

In vitro regulation of a SIN3-dependent DNA-binding activity by stimulatory and inhibitory factors

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231578

The adenovirus major late transcription factor USF is a member of the helix-loop-helix group of regulatory proteins and binds to DNA as a dimer

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231578

The Saccharomyces cerevisiae SIN3 gene, a negative regulator of HO, contains four paired amphipathic helix motifs

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231578

An amino-terminal c-myc domain required for neoplastic transformation activates transcription

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231578

Fos and jun cooperate in transcriptional regulation via heterologous activation domains

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231578

Max: a helix-loop-helix zipper protein that forms a sequence-specific DNA-binding complex with Myc

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231578

Association of Myn, the murine homolog of Max, with c-Myc stimulates methylation-sensitive DNA binding and ras cotransformation

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231578

Ssn6-Tup1 is a general repressor of transcription in yeast

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231578

Myc and Max: a putative transcriptional complex in search of a cellular target

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231578

The functions of Myc proteins

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231578

Myc and Max proteins possess distinct transcriptional activities

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231578

Transcriptional activation by the human c-Myc oncoprotein in yeast requires interaction with Max.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231578

Definition of the transcriptional activation domain of recombinant 43-kilodalton USF.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231578

Autocrine growth induced by kinase type oncogenes in myeloid cells requires AP-1 and NF-M, a myeloid specific, C/EBP-like factor

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231578

Proteins of the Myc network: essential regulators of cell growth and differentiation.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231578

Differential regulation of Max and role of c-Myc during erythroid and myelomonocytic differentiation of K562 cells

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231578

Repression of Myc-Ras cotransformation by Mad is mediated by multiple protein-protein interactions

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231578

Regulation of Myc and Mad during epidermal differentiation and HPV-associated tumorigenesis.

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231578

A switch from Myc:Max to Mad:Max heterocomplexes accompanies monocyte/macrophage differentiation.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231578

Mot1, a global repressor of RNA polymerase II transcription, inhibits TBP binding to DNA by an ATP-dependent mechanism.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231578

Interaction of a gene-specific transcription factor with the adenovirus major late promoter upstream of the TATA box region.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231578

Transcriptional regulation by Fos and Jun in vitro: interaction among multiple activator and regulatory domains

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231578

An embryonically expressed gene is a target for c-Myc regulation via the c-Myc-binding sequence

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231578

Oncogenic activity of the c-Myc protein requires dimerization with Max.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231578

Association of an activator with an RNA polymerase II holoenzyme

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231578

Control of transcription by Krüppel through interactions with TFIIB and TFIIE beta.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231578

Effects of the MYC oncogene antagonist, MAD, on proliferation, cell cycling and the malignant phenotype of human brain tumour cells

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231578

Expression of mad, mxi1, max and c-myc during induced differentiation of hematopoietic cells: opposite regulation of mad and c-myc

20 August 2018

1 reference

12 December 2020

Functional dissection of the yeast Cyc8–Tupl transcriptional co-repressor complex

1 reference

12 December 2020

Distinct TPR motifs of Cyc8 are involved in recruiting the Cyc8-Tup1 corepressor complex to differentially regulated promoters

1 reference

12 December 2020

Bidirectional SV40 transcription mediated by tandem Sp1 binding interactions

1 reference

12 December 2020

GAL4 derivatives function alone and synergistically with mammalian activators in vitro

1 reference

12 December 2020

Transcriptional activities of the Myc and Max proteins in mammalian cells

1 reference

12 December 2020

Identifiers

DOI

10.1128/MCB.16.10.5772

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8816491%20AND%20SRC:MED&resulttype=core&format=json

19 October 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8816491%20AND%20SRC:MED&resulttype=core&format=json

19 October 2019

PubMed publication ID

8816491

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8816491%20AND%20SRC:MED&resulttype=core&format=json