Overview: Structural Biology of Integrins (Q37930501)

25 August 2017

1 reference

title

Overview: structural biology of integrins (English)

1 reference

25 August 2017

Overview: Structural Biology of Integrins (English)

1 reference

Crossref

DOI

https://api.crossref.org/works/10.1007/978-1-61779-166-6_7

12 December 2024

1 reference

Guanyuan Fu

1 reference

25 August 2017

Wei Wang

series ordinal

1 reference

25 August 2017

Bing-Hao Luo

series ordinal

1 reference

25 August 2017

language of work or name

English

0 references

publication date

1 January 2012

1 reference

25 August 2017

2012

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=21909908

full work available at URL

12 December 2024

http://link.springer.com/content/pdf/10.1007/978-1-61779-166-6_7

1 reference

Crossref

DOI

https://api.crossref.org/works/10.1007/978-1-61779-166-6_7

Methods in Molecular Biology

12 December 2024

published in

1 reference

25 August 2017

volume

757

1 reference

25 August 2017

page(s)

81-99

1 reference

The structure of a receptor with two associating transmembrane domains on the cell surface: integrin alphaIIbbeta3.

25 August 2017

cites work

1 reference

9 October 2024

https://opencitations.net/index/api/v1/citations/10.1016/J.MOLCEL.2009.02.022

Integrins: versatility, modulation, and signaling in cell adhesion

1 reference

https://api.crossref.org/works/10.1007/978-1-61779-166-6_7

Traffic signals for lymphocyte recirculation and leukocyte emigration: the multistep paradigm

12 December 2024

1 reference

https://api.crossref.org/works/10.1007/978-1-61779-166-6_7

Integrins: bidirectional, allosteric signaling machines

12 December 2024

1 reference

https://api.crossref.org/works/10.1007/978-1-61779-166-6_7

Crystal structure of the extracellular segment of integrin alpha Vbeta3 in complex with an Arg-Gly-Asp ligand

12 December 2024

1 reference

https://api.crossref.org/works/10.1007/978-1-61779-166-6_7

Crystal structure of the extracellular segment of integrin alpha Vbeta3

12 December 2024

1 reference

https://api.crossref.org/works/10.1007/978-1-61779-166-6_7

Structure of a Complete Integrin Ectodomain in a Physiologic Resting State and Activation and Deactivation by Applied Forces

12 December 2024

1 reference

https://api.crossref.org/works/10.1007/978-1-61779-166-6_7

Structural basis of integrin regulation and signaling

12 December 2024

1 reference

https://api.crossref.org/works/10.1007/978-1-61779-166-6_7

Structural basis for allostery in integrins and binding to fibrinogen-mimetic therapeutics

12 December 2024

1 reference

https://api.crossref.org/works/10.1007/978-1-61779-166-6_7

Structure of integrin alpha5beta1 in complex with fibronectin

12 December 2024

1 reference

https://api.crossref.org/works/10.1007/978-1-61779-166-6_7

Bidirectional transmembrane signaling by cytoplasmic domain separation in integrins

12 December 2024

1 reference

https://api.crossref.org/works/10.1007/978-1-61779-166-6_7

Global conformational rearrangements in integrin extracellular domains in outside-in and inside-out signaling

12 December 2024

1 reference

https://api.crossref.org/works/10.1007/978-1-61779-166-6_7

Crystal structure of the A domain from the alpha subunit of integrin CR3 (CD11b/CD18)

12 December 2024

1 reference

https://api.crossref.org/works/10.1007/978-1-61779-166-6_7

Folding of the N-terminal, ligand-binding region of integrin alpha-subunits into a beta-propeller domain

12 December 2024

1 reference

https://api.crossref.org/works/10.1007/978-1-61779-166-6_7

Amino acid residues in the alpha IIb subunit that are critical for ligand binding to integrin alpha IIbbeta 3 are clustered in the beta-propeller model

12 December 2024

1 reference

https://api.crossref.org/works/10.1007/978-1-61779-166-6_7

Structural and functional studies with antibodies to the integrin beta 2 subunit. A model for the I-like domain

12 December 2024

1 reference

https://api.crossref.org/works/10.1007/978-1-61779-166-6_7

Cysteine-rich module structure reveals a fulcrum for integrin rearrangement upon activation

12 December 2024

1 reference

https://api.crossref.org/works/10.1007/978-1-61779-166-6_7

The crystal structure of the plexin-semaphorin-integrin domain/hybrid domain/I-EGF1 segment from the human integrin beta2 subunit at 1.8-A resolution.

12 December 2024

1 reference

https://api.crossref.org/works/10.1007/978-1-61779-166-6_7

Breaking the integrin hinge. A defined structural constraint regulates integrin signaling

12 December 2024

1 reference

https://api.crossref.org/works/10.1007/978-1-61779-166-6_7

Structures of the alpha L I domain and its complex with ICAM-1 reveal a shape-shifting pathway for integrin regulation

12 December 2024

1 reference

https://api.crossref.org/works/10.1007/978-1-61779-166-6_7

Structural basis of collagen recognition by integrin alpha2beta1

12 December 2024

1 reference

https://api.crossref.org/works/10.1007/978-1-61779-166-6_7

Activation of integrin beta-subunit I-like domains by one-turn C-terminal alpha-helix deletions

12 December 2024

1 reference

https://api.crossref.org/works/10.1007/978-1-61779-166-6_7

Locking the beta3 integrin I-like domain into high and low affinity conformations with disulfides

12 December 2024

1 reference

https://api.crossref.org/works/10.1007/978-1-61779-166-6_7

Identification of integrin beta subunit mutations that alter heterodimer function in situ

12 December 2024

1 reference

https://api.crossref.org/works/10.1007/978-1-61779-166-6_7

Novel activating and inactivating mutations in the integrin beta1 subunit A domain.

12 December 2024

1 reference

https://api.crossref.org/works/10.1007/978-1-61779-166-6_7

Conformational Changes in the Integrin βA Domain Provide a Mechanism for Signal Transduction via Hybrid Domain Movement

12 December 2024

1 reference

https://api.crossref.org/works/10.1007/978-1-61779-166-6_7

The integrin alpha-subunit leg extends at a Ca2+-dependent epitope in the thigh/genu interface upon activation

12 December 2024

1 reference

https://api.crossref.org/works/10.1007/978-1-61779-166-6_7

An isolated, surface-expressed I domain of the integrin alphaLbeta2 is sufficient for strong adhesive function when locked in the open conformation with a disulfide bond.

12 December 2024

1 reference

https://api.crossref.org/works/10.1007/978-1-61779-166-6_7

Defining extracellular integrin alpha-chain sites that affect cell adhesion and adhesion strengthening without altering soluble ligand binding

12 December 2024

1 reference

https://api.crossref.org/works/10.1007/978-1-61779-166-6_7

The lymphocyte function-associated antigen 1 I domain is a transient binding module for intercellular adhesion molecule (ICAM)-1 and ICAM-3 in hydrodynamic flow

12 December 2024

1 reference

https://api.crossref.org/works/10.1007/978-1-61779-166-6_7

The relative influence of metal ion binding sites in the I-like domain and the interface with the hybrid domain on rolling and firm adhesion by integrin alpha4beta7.

12 December 2024

1 reference

https://api.crossref.org/works/10.1007/978-1-61779-166-6_7

Role of ADMIDAS cation-binding site in ligand recognition by integrin alpha 5 beta 1.

12 December 2024

1 reference

https://api.crossref.org/works/10.1007/978-1-61779-166-6_7

Bistable regulation of integrin adhesiveness by a bipolar metal ion cluster

12 December 2024

1 reference

https://api.crossref.org/works/10.1007/978-1-61779-166-6_7

Intersubunit signal transmission in integrins by a receptor-like interaction with a pull spring.

12 December 2024

1 reference

https://api.crossref.org/works/10.1007/978-1-61779-166-6_7

Does the integrin alphaA domain act as a ligand for its betaA domain?

12 December 2024

1 reference

https://api.crossref.org/works/10.1007/978-1-61779-166-6_7

NMR and mutagenesis evidence for an I domain allosteric site that regulates lymphocyte function-associated antigen 1 ligand binding

12 December 2024

1 reference

https://api.crossref.org/works/10.1007/978-1-61779-166-6_7

Allosteric beta1 integrin antibodies that stabilize the low affinity state by preventing the swing-out of the hybrid domain

12 December 2024

1 reference

https://api.crossref.org/works/10.1007/978-1-61779-166-6_7

Electron tomography reveals diverse conformations of integrin alphaIIbbeta3 in the active state

12 December 2024

1 reference

https://api.crossref.org/works/10.1007/978-1-61779-166-6_7

Activation of leukocyte beta2 integrins by conversion from bent to extended conformations

12 December 2024

1 reference

https://api.crossref.org/works/10.1007/978-1-61779-166-6_7

Structure of an integrin-ligand complex deduced from solution x-ray scattering and site-directed mutagenesis.

12 December 2024

1 reference

https://api.crossref.org/works/10.1007/978-1-61779-166-6_7

Stabilizing the open conformation of the integrin headpiece with a glycan wedge increases affinity for ligand

12 December 2024

1 reference

https://api.crossref.org/works/10.1007/978-1-61779-166-6_7

The integrin alpha L beta 2 hybrid domain serves as a link for the propagation of activation signal from its stalk regions to the I-like domain

12 December 2024

1 reference

https://api.crossref.org/works/10.1007/978-1-61779-166-6_7

Epitope mapping of monoclonal antibody to integrin alphaL beta2 hybrid domain suggests different requirements of affinity states for intercellular adhesion molecules (ICAM)-1 and ICAM-3 binding

12 December 2024

1 reference

https://api.crossref.org/works/10.1007/978-1-61779-166-6_7

A novel adaptation of the integrin PSI domain revealed from its crystal structure

12 December 2024

1 reference

https://api.crossref.org/works/10.1007/978-1-61779-166-6_7

Evidence that monoclonal antibodies directed against the integrin beta subunit plexin/semaphorin/integrin domain stimulate function by inducing receptor extension.

12 December 2024

1 reference

https://api.crossref.org/works/10.1007/978-1-61779-166-6_7

Topography of ligand-induced binding sites, including a novel cation-sensitive epitope (AP5) at the amino terminus, of the human integrin beta 3 subunit

12 December 2024

1 reference

https://api.crossref.org/works/10.1007/978-1-61779-166-6_7

A site involving the "hybrid" and PSI homology domains of GPIIIa (beta 3-integrin subunit) is a common target for antibodies associated with quinine-induced immune thrombocytopenia

12 December 2024

1 reference

https://api.crossref.org/works/10.1007/978-1-61779-166-6_7

FRET detection of cellular alpha4-integrin conformational activation.

12 December 2024

1 reference

https://api.crossref.org/works/10.1007/978-1-61779-166-6_7

C-terminal opening mimics 'inside-out' activation of integrin alpha5beta1

12 December 2024

1 reference

https://api.crossref.org/works/10.1007/978-1-61779-166-6_7

Modulation of CD11b/CD18 adhesive activity by its extracellular, membrane-proximal regions

12 December 2024

1 reference

https://api.crossref.org/works/10.1007/978-1-61779-166-6_7

Association of the membrane proximal regions of the alpha and beta subunit cytoplasmic domains constrains an integrin in the inactive state

12 December 2024

1 reference

https://api.crossref.org/works/10.1007/978-1-61779-166-6_7

Integrin cytoplasmic domains mediate inside-out signal transduction

12 December 2024

1 reference

https://api.crossref.org/works/10.1007/978-1-61779-166-6_7

Modulation of the affinity of integrin alpha IIb beta 3 (GPIIb-IIIa) by the cytoplasmic domain of alpha IIb

12 December 2024

1 reference

https://api.crossref.org/works/10.1007/978-1-61779-166-6_7

Membrane-mediated structural transitions at the cytoplasmic face during integrin activation

12 December 2024

1 reference

https://api.crossref.org/works/10.1007/978-1-61779-166-6_7

Solution structures of the cytoplasmic tail complex from platelet integrin alpha IIb- and beta 3-subunits

12 December 2024

1 reference

https://api.crossref.org/works/10.1007/978-1-61779-166-6_7

A structural mechanism of integrin alpha(IIb)beta(3) "inside-out" activation as regulated by its cytoplasmic face

12 December 2024

1 reference

https://api.crossref.org/works/10.1007/978-1-61779-166-6_7

NMR analysis of structure and dynamics of the cytosolic tails of integrin alpha IIb beta 3 in aqueous solution

12 December 2024

1 reference

https://api.crossref.org/works/10.1007/978-1-61779-166-6_7

RAPL, a Rap1-binding molecule that mediates Rap1-induced adhesion through spatial regulation of LFA-1

12 December 2024

1 reference

https://api.crossref.org/works/10.1007/978-1-61779-166-6_7

Talin Binding to Integrin ß Tails: A Final Common Step in Integrin Activation

12 December 2024

1 reference

https://api.crossref.org/works/10.1007/978-1-61779-166-6_7

Structural determinants of integrin recognition by talin

12 December 2024

1 reference

https://api.crossref.org/works/10.1007/978-1-61779-166-6_7

The Talin head domain binds to integrin beta subunit cytoplasmic tails and regulates integrin activation

12 December 2024

1 reference

https://api.crossref.org/works/10.1007/978-1-61779-166-6_7

The molecular basis of filamin binding to integrins and competition with talin

12 December 2024

1 reference

https://api.crossref.org/works/10.1007/978-1-61779-166-6_7

Domain-specific interactions of talin with the membrane-proximal region of the integrin beta3 subunit.

12 December 2024

1 reference

https://api.crossref.org/works/10.1007/978-1-61779-166-6_7

A specific interface between integrin transmembrane helices and affinity for ligand

12 December 2024

1 reference

https://api.crossref.org/works/10.1007/978-1-61779-166-6_7

Transmembrane domain helix packing stabilizes integrin alphaIIbbeta3 in the low affinity state

12 December 2024

1 reference

https://api.crossref.org/works/10.1007/978-1-61779-166-6_7

Disrupting integrin transmembrane domain heterodimerization increases ligand binding affinity, not valency or clustering.

12 December 2024

1 reference

https://api.crossref.org/works/10.1007/978-1-61779-166-6_7

A push-pull mechanism for regulating integrin function

12 December 2024

1 reference

https://api.crossref.org/works/10.1007/978-1-61779-166-6_7

Structure of the integrin beta3 transmembrane segment in phospholipid bicelles and detergent micelles

12 December 2024

1 reference

https://api.crossref.org/works/10.1007/978-1-61779-166-6_7

Structure of the Integrin IIb Transmembrane Segment

12 December 2024

1 reference

https://api.crossref.org/works/10.1007/978-1-61779-166-6_7

The structure of the integrin alphaIIbbeta3 transmembrane complex explains integrin transmembrane signalling

12 December 2024

1 reference

https://api.crossref.org/works/10.1007/978-1-61779-166-6_7

Integrins: dynamic scaffolds for adhesion and signaling in platelets

12 December 2024

1 reference

https://api.crossref.org/works/10.1007/978-1-61779-166-6_7

Integrin signalling during tumour progression

12 December 2024

1 reference

https://api.crossref.org/works/10.1007/978-1-61779-166-6_7

Integrin-linked kinase: integrin's mysterious partner

12 December 2024

1 reference

https://api.crossref.org/works/10.1007/978-1-61779-166-6_7

Cell migration: integrating signals from front to back

12 December 2024

1 reference

https://api.crossref.org/works/10.1007/978-1-61779-166-6_7

12 December 2024

Identifiers

DOI

1 reference

25 August 2017

1 reference