Global conformational rearrangements in integrin extracellular domains in outside-in and inside-out signaling (Q44136286)

30 November 2017

title

Global conformational rearrangements in integrin extracellular domains in outside-in and inside-out signaling (English)

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30 November 2017

Junichi Takagi

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30 November 2017

Benjamin M Petre

series ordinal

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30 November 2017

Thomas Walz

series ordinal

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30 November 2017

Timothy A Springer

series ordinal

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30 November 2017

language of work or name

English

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publication date

1 September 2002

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30 November 2017

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30 November 2017

volume

110

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30 November 2017

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30 November 2017

page(s)

599-511

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The CCP4 suite: programs for protein crystallography

30 November 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900935-2

7 January 2021

Are changes in integrin affinity and conformation overemphasized?

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900935-2

7 January 2021

Divalent cations and ligands induce conformational changes that are highly divergent among beta1 integrins

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900935-2

7 January 2021

Flow cytometric measurement of kinetic and equilibrium binding parameters of arginine-glycine-aspartic acid ligands in binding to glycoprotein IIb/IIIa on platelets

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900935-2

7 January 2021

Cysteine-rich module structure reveals a fulcrum for integrin rearrangement upon activation

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900935-2

7 January 2021

Evidence that thrombocytopenia observed in humans treated with orally bioavailable glycoprotein IIb/IIIa antagonists is immune mediated

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900935-2

7 January 2021

Integrin alpha v beta 3 antagonists promote tumor regression by inducing apoptosis of angiogenic blood vessels

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900935-2

7 January 2021

The atomic structure of protein-protein recognition sites

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900935-2

7 January 2021

N-Methylated cyclic RGD peptides as highly active and selective alpha(V)beta(3) integrin antagonists

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900935-2

7 January 2021

Ligands "activate" integrin alpha IIb beta 3 (platelet GPIIb-IIIa).

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900935-2

7 January 2021

Non-peptide GPIIb/IIIa inhibitors. 20. Centrally constrained thienothiophene alpha-sulfonamides are potent, long acting in vivo inhibitors of platelet aggregation

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900935-2

7 January 2021

Transmembrane signaling in bacterial chemoreceptors

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900935-2

7 January 2021

SPIDER and WEB: processing and visualization of images in 3D electron microscopy and related fields

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900935-2

7 January 2021

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900935-2

1 reference

7 January 2021

Integrin associated proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900935-2

7 January 2021

Determination of kinetic constants for the interaction between the platelet glycoprotein IIb-IIIa and fibrinogen by means of surface plasmon resonance

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900935-2

7 January 2021

Integrin affinity modulation

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900935-2

7 January 2021

Breaking the integrin hinge. A defined structural constraint regulates integrin signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900935-2

7 January 2021

Epitope mapping of antibodies to the C-terminal region of the integrin beta 2 subunit reveals regions that become exposed upon receptor activation

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900935-2

7 January 2021

Association of the membrane proximal regions of the alpha and beta subunit cytoplasmic domains constrains an integrin in the inactive state

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900935-2

7 January 2021

Manipulation of ligand binding affinity by exploitation of conformational coupling

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900935-2

7 January 2021

Mechanisms and consequences of affinity modulation of integrin alpha(V)beta(3) detected with a novel patch-engineered monovalent ligand

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900935-2

7 January 2021

Mechanisms of cooperativity and allosteric regulation in proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900935-2

7 January 2021

Erythropoietin receptor activation by a ligand-induced conformation change

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900935-2

7 January 2021

Platelet glycoprotein IIb-IIIa antagonists as prototypical integrin blockers: novel parenteral and potential oral antithrombotic agents

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900935-2

7 January 2021

Networks and crosstalk: integrin signalling spreads.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900935-2

7 January 2021

Conformational regulation of integrin structure and function

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900935-2

7 January 2021

C-terminal opening mimics 'inside-out' activation of integrin alpha5beta1

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900935-2

7 January 2021

A structural mechanism of integrin alpha(IIb)beta(3) "inside-out" activation as regulated by its cytoplasmic face

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900935-2

7 January 2021

Crystal structure of the extracellular segment of integrin alpha Vbeta3

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900935-2

7 January 2021

Crystal structure of the extracellular segment of integrin alpha Vbeta3 in complex with an Arg-Gly-Asp ligand

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900935-2

7 January 2021

Mechanism of integrin activation by disulfide bond reduction

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900935-2

7 January 2021

Amino acid residues in the PSI domain and cysteine-rich repeats of the integrin beta2 subunit that restrain activation of the integrin alpha(X)beta(2).

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900935-2

7 January 2021

10.1016/S0092-8674(02)00935-2

Identifiers

DOI

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30 November 2017

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