What's the hype about CDK5RAP2? (Q37843832)

24 August 2017

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title

What's the hype about CDK5RAP2? (English)

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24 August 2017

Angela M Kaindl

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24 August 2017

Nadine Kraemer

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24 August 2017

Lina Issa

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24 August 2017

Stefanie C R Hauck

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24 August 2017

Shyamala Mani

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24 August 2017

Olaf Ninnemann

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24 August 2017

publication date

17 February 2011

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Cellular and Molecular Life Sciences

24 August 2017

published in

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24 August 2017

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24 August 2017

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24 August 2017

page(s)

1719-1736

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Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro

24 August 2017

cites work

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https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

Cloning of three novel neuronal Cdk5 activator binding proteins

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

Identification of a common protein association region in the neuronal Cdk5 activator

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

Identification and structure characterization of a Cdk inhibitory peptide derived from neuronal-specific Cdk5 activator

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

CDK5RAP2 is a pericentriolar protein that functions in centrosomal attachment of the gamma-tubulin ring complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

Novel meiosis-specific isoform of mammalian SMC1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

Molecular evolution of the brain size regulator genes CDK5RAP2 and CENPJ

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

SMC proteins and chromosome mechanics: from bacteria to humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

Predicting coiled coils from protein sequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

The ABCs of SMC proteins: two-armed ATPases for chromosome condensation, cohesion, and repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

Cdk5rap2 regulates centrosome function and chromosome segregation in neuronal progenitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

Cdk5rap2 interacts with pericentrin to maintain the neural progenitor pool in the developing neocortex

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

Cdk5 activator-binding protein C53 regulates apoptosis induced by genotoxic stress via modulating the G2/M DNA damage checkpoint

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

Tumor suppressor protein C53 antagonizes checkpoint kinases to promote cyclin-dependent kinase 1 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

A centrosomal mechanism involving CDK5RAP2 and CENPJ controls brain size

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

Cep68 and Cep215 (Cdk5rap2) are required for centrosome cohesion

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

CDK5RAP2 regulates centriole engagement and cohesion in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

Conversion of p35 to p25 deregulates Cdk5 activity and promotes neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

Cyclin-dependent kinase 5 is essential for neuronal cell cycle arrest and differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

An unusual member of the Cdk family: Cdk5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

Role of cyclin-dependent kinase 5 and its activator P35 in local axon and growth cone stabilization

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

Cyclin-dependent kinase 5 activity regulates pain signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

Cortical interneurons require p35/Cdk5 for their migration and laminar organization

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

Nuclear localization of Cdk5 is a key determinant in the postmitotic state of neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

A third novel locus for primary autosomal recessive microcephaly maps to chromosome 9q34.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

Identification of microcephalin, a protein implicated in determining the size of the human brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

Primary autosomal recessive microcephaly (MCPH1) maps to chromosome 8p22-pter

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

The second locus for autosomal recessive primary microcephaly (MCPH2) maps to chromosome 19q13.1-13.2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

WDR62 is associated with the spindle pole and is mutated in human microcephaly

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

Mutations in WDR62, encoding a centrosome-associated protein, cause microcephaly with simplified gyri and abnormal cortical architecture

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

Primary autosomal recessive microcephaly: homozygosity mapping of MCPH4 to chromosome 15.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

Mutations in centrosomal protein CEP152 in primary microcephaly families linked to MCPH4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

A fifth locus for primary autosomal recessive microcephaly maps to chromosome 1q31.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

ASPM mutations identified in patients with primary microcephaly and seizures

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

A novel locus for autosomal recessive primary microcephaly (MCPH6) maps to 13q12.2

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

Mutations in STIL, encoding a pericentriolar and centrosomal protein, cause primary microcephaly

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

Expanding the clinical and neuroradiologic phenotype of primary microcephaly due to ASPM mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

Autosomal recessive primary microcephaly (MCPH): a review of clinical, molecular, and evolutionary findings

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

Maintaining the proper connection between the centrioles and the pericentriolar matrix requires Drosophila centrosomin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

Centrosome control of the cell cycle

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

Proper recruitment of gamma-tubulin and D-TACC/Msps to embryonic Drosophila centrosomes requires Centrosomin Motif 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

Zygotic development without functional mitotic centrosomes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

Making microtubules and mitotic spindles in cells without functional centrosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

The centrosome in vertebrates: more than a microtubule-organizing center

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

Centrosome composition and microtubule anchoring mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

Microtubule-organizing centres: a re-evaluation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

The centrosome in higher organisms: structure, composition, and duplication

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

Mitosis-specific anchoring of gamma tubulin complexes by pericentrin controls spindle organization and mitotic entry

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

Loss of centrosome integrity induces p38-p53-p21-dependent G1-S arrest

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

CDK5RAP2 is required for spindle checkpoint function

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

The spindle-assembly checkpoint in space and time

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

Ubiquitin ligases: cell-cycle control and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

CLIPs and CLASPs and cellular dynamics

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

Tracking the ends: a dynamic protein network controls the fate of microtubule tips

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

Mitotic spindle regulation by Nde1 controls cerebral cortical size

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

Aspm specifically maintains symmetric proliferative divisions of neuroepithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

G protein betagamma subunits and AGS3 control spindle orientation and asymmetric cell fate of cerebral cortical progenitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

Cdk5 regulates accurate maturation of newborn granule cells in the adult hippocampus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

Neurabin-I is phosphorylated by Cdk5: implications for neuronal morphogenesis and cortical migration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

Neuronal morphogenesis is regulated by the interplay between cyclin-dependent kinase 5 and the ubiquitin ligase mind bomb 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

Cyclin-dependent kinase 5 and neuronal migration in the neocortex

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

Targeted disruption of the cyclin-dependent kinase 5 gene results in abnormal corticogenesis, neuronal pathology and perinatal death

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

Mice lacking p35, a neuronal specific activator of Cdk5, display cortical lamination defects, seizures, and adult lethality

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

A novel disruption of cortical development in p35(-/-) mice distinct from reeler

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

Transcriptional regulation of cortical neuron migration by POU domain factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

Role of heat-shock factor 2 in cerebral cortex formation and as a regulator of p35 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

Positive selection in ASPM is correlated with cerebral cortex evolution across primates but not with whole-brain size

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

Evolution. Are human brains still evolving? Brain genes show signs of selection

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

Bruce Lahn profile. Links between brain genes, evolution, and cognition challenged

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

BRUCE LAHN PROFILE: Brain Man Makes Waves With Claims of Recent Human Evolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

Cytoskeletal genes regulating brain size

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

Comment on "Ongoing adaptive evolution of ASPM, a brain size determinant in Homo sapiens" and "Microcephalin, a gene regulating brain size, continues to evolve adaptively in humans".

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

Reconstructing the evolutionary history of microcephalin, a gene controlling human brain size

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

Adaptive evolution of ASPM, a major determinant of cerebral cortical size in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

Microcephalin, a Gene Regulating Brain Size, Continues to Evolve Adaptively in Humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

The spread of alphabetical writing may have favored the latest variant of the ASPM gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

Accelerated evolution of the ASPM gene controlling brain size begins prior to human brain expansion

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

Ongoing adaptive evolution of ASPM, a brain size determinant in Homo sapiens.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

Evolution of primary microcephaly genes and the enlargement of primate brains

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

A novel domain suggests a ciliary function for ASPM, a brain size determining gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

Genetic, physiologic and ecogeographic factors contributing to variation in Homo sapiens: Homo floresiensis reconsidered

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

Evolutionary Genetics: is brain evolution still continuing in modern humans?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

A common SNP of MCPH1 is associated with cranial volume variation in Chinese population.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

Molecular evolution of microcephalin, a gene determining human brain size

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

Genetic links between brain development and brain evolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

Sex-dependent association of common variants of microcephaly genes with brain structure

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

Many roads lead to primary autosomal recessive microcephaly

21 January 2018

1 reference

12 December 2020

[Study of a familial case of microcephaly and micrencephaly. Clinical and anatomo-pathologic considerations on a preliminary basis]

1 reference

12 December 2020

Taxanes, microtubules and chemoresistant breast cancer.

1 reference

12 December 2020

Evolution of the human ASPM gene, a major determinant of brain size

1 reference

12 December 2020

[Familial microcephalies due to cerebral malformation. Anatomical and clinical study]

1 reference

12 December 2020

Migration defects of cdk5(-/-) neurons in the developing cerebellum is cell autonomous

1 reference

12 December 2020

Pacing below the ventricular rate in terminating ventricular tachycardia and flutter

1 reference

12 December 2020

Layering defect in p35 deficiency is linked to improper neuronal-glial interaction in radial migration

1 reference

12 December 2020

Conserved motif of CDK5RAP2 mediates its localization to centrosomes and the Golgi complex

1 reference

12 December 2020

Interaction of CDK5RAP2 with EB1 to track growing microtubule tips and to regulate microtubule dynamics

1 reference

12 December 2020

CEP215 is involved in the dynein-dependent accumulation of pericentriolar matrix proteins for spindle pole formation

1 reference

12 December 2020

The centrosomin protein is required for centrosome assembly and function during cleavage in Drosophila.

1 reference

12 December 2020

10.1007/S00018-011-0635-4

Identifiers

DOI

1 reference

24 August 2017

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