New insights into the molecular mechanisms of general anaesthetics (Q37782116)

23 August 2017

8 references

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31 July 2019

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15 December 2019

8 September 2020

29 April 2021

New insights into the molecular mechanisms of general anaesthetics (English)

1 reference

23 August 2017

cell surface receptor

1 reference

31 July 2019

1 reference

12 September 2019

1 reference

28 November 2019

1 reference

15 December 2019

1 reference

8 September 2020

1 reference

29 April 2021

P-L Chau

1 reference

23 August 2017

language of work or name

English

0 references

publication date

1 September 2010

9 references

full work available at URL

23 August 2017

20 June 2019

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31 July 2019

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28 November 2019

15 December 2019

8 September 2020

29 April 2021

https://europepmc.org/articles/pmc2989583?pdf=render

1 reference

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20735416/pdf/?tool=EBI

22 June 2024

1 reference

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20735416/?tool=EBI

22 June 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20735416

https://europepmc.org/articles/PMC2989583

22 June 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20735416

https://europepmc.org/articles/PMC2989583?pdf=render

22 June 2024

1 reference

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https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2Fj.1476-5381.2010.00891.x

22 June 2024

1 reference

https://api.crossref.org/works/10.1111/J.1476-5381.2010.00891.X

https://bpspubs.onlinelibrary.wiley.com/doi/pdf/10.1111/j.1476-5381.2010.00891.x

22 June 2024

1 reference

https://api.crossref.org/works/10.1111/J.1476-5381.2010.00891.X

British Journal of Pharmacology

22 June 2024

published in

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161

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23 August 2017

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288-307

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Creative Commons Attribution 2.5 Generic

23 August 2017

2 references

8 September 2020

X-ray structure, symmetry and mechanism of an AMPA-subtype glutamate receptor

29 April 2021

cites work

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Gamma-amino butyric acid type A receptor mutations at beta2N265 alter etomidate efficacy while preserving basal and agonist-dependent activity

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Mechanism of interaction between the general anesthetic halothane and a model ion channel protein, III: Molecular dynamics simulation incorporating a cyanophenylalanine spectroscopic probe

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Mechanism of interaction between the general anesthetic halothane and a model ion channel protein, II: Fluorescence and vibrational spectroscopy using a cyanophenylalanine probe

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Glycine receptors contribute to hypnosis induced by ethanol

6 September 2017

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Behavior and cellular evidence for propofol-induced hypnosis involving brain glycine receptors

6 September 2017

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Distinct structural changes in the GABAA receptor elicited by pentobarbital and GABA.

6 September 2017

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Resolving voltage-dependent structural changes of a membrane photoreceptor by surface-enhanced IR difference spectroscopy

6 September 2017

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Menthol shares general anesthetic activity and sites of action on the GABA(A) receptor with the intravenous agent, propofol

6 September 2017

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General anaesthesia: from molecular targets to neuronal pathways of sleep and arousal

6 September 2017

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Interaction of anesthetics with open and closed conformations of a potassium channel studied via molecular dynamics and normal mode analysis

6 September 2017

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Four-alpha-helix bundle with designed anesthetic binding pockets. Part I: structural and dynamical analyses

6 September 2017

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Four-alpha-helix bundle with designed anesthetic binding pockets. Part II: halothane effects on structure and dynamics

6 September 2017

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Bubbles, gating, and anesthetics in ion channels

6 September 2017

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Competitive inhibition at the glycine site of the N-methyl-D-aspartate receptor by the anesthetics xenon and isoflurane: evidence from molecular modeling and electrophysiology

6 September 2017

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MK-801 enhances gabaculine-induced loss of the righting reflex in mice, but not immobility

6 September 2017

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Neural pathways associated with loss of consciousness caused by intracerebral microinjection of GABA A-active anesthetics

6 September 2017

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Effects of an amphipathic alpha-helical peptide on lateral pressure and water penetration in phosphatidylcholine and monoolein mixed membranes

6 September 2017

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Endogenous neurosteroids regulate GABAA receptors through two discrete transmembrane sites

6 September 2017

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6 September 2017

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Partitioning of anesthetics into a lipid bilayer and their interaction with membrane-bound peptide bundles

6 September 2017

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An isoflurane- and alcohol-insensitive mutant GABA(A) receptor alpha(1) subunit with near-normal apparent affinity for GABA: characterization in heterologous systems and production of knockin mice

6 September 2017

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Sleep, anesthesiology, and the neurobiology of arousal state control.

6 September 2017

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6 September 2017

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Emerging molecular mechanisms of general anesthetic action.

6 September 2017

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Effect of N-methyl-D-aspartate receptor epsilon1 subunit gene disruption of the action of general anesthetic drugs in mice

6 September 2017

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Refined structure of the nicotinic acetylcholine receptor at 4A resolution

6 September 2017

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Concentration effects of volatile anesthetics on the properties of model membranes: a coarse-grain approach

6 September 2017

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TREK-1, a K+ channel involved in neuroprotection and general anesthesia

6 September 2017

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Two-pore-domain K+ channels are a novel target for the anesthetic gases xenon, nitrous oxide, and cyclopropane

6 September 2017

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6 September 2017

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Large-scale molecular dynamics simulations of general anesthetic effects on the ion channel in the fully hydrated membrane: the implication of molecular mechanisms of general anesthesia

6 September 2017

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Tryptophan scanning mutagenesis in TM4 of the GABA(A) receptor alpha1 subunit: implications for modulation by inhaled anesthetics and ion channel structure

6 September 2017

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Effects of the nonimmobilizer hexafluroethane on the model membrane dimyristoylphosphatidylcholine

6 September 2017

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Nuclear Overhauser enhancement spectroscopy cross-relaxation rates and ethanol distribution across membranes

6 September 2017

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Methionine 286 in transmembrane domain 3 of the GABAA receptor beta subunit controls a binding cavity for propofol and other alkylphenol general anesthetics

6 September 2017

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6 September 2017

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Breaking the Meyer-Overton rule: predicted effects of varying stiffness and interfacial activity on the intrinsic potency of anesthetics

6 September 2017

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Binding of the general anesthetics propofol and halothane to human serum albumin. High resolution crystal structures

6 September 2017

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Specific binding sites for alcohols and anesthetics on ligand-gated ion channels

6 September 2017

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The actions of ether, alcohol and alkane general anaesthetics on GABAA and glycine receptors and the effects of TM2 and TM3 mutations

6 September 2017

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Subunit mutations affect ethanol actions on GABA(A) receptors expressed in Xenopus oocytes

6 September 2017

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Inhalational anesthetics activate two-pore-domain background K+ channels

6 September 2017

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Stoichiometry of a ligand-gated ion channel determined by fluorescence energy transfer

6 September 2017

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Effects of anesthetics on the structure of a phospholipid bilayer: molecular dynamics investigation of halothane in the hydrated liquid crystal phase of dipalmitoylphosphatidylcholine

6 September 2017

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International Union of Pharmacology. XV. Subtypes of gamma-aminobutyric acidA receptors: classification on the basis of subunit structure and receptor function

6 September 2017

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A neuronal two P domain K+ channel stimulated by arachidonic acid and polyunsaturated fatty acids.

6 September 2017

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Nitrous oxide (laughing gas) is an NMDA antagonist, neuroprotectant and neurotoxin

6 September 2017

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Stereoselective effects of etomidate optical isomers on gamma-aminobutyric acid type A receptors and animals

6 September 2017

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Stoichiometry of Recombinant N-Methyl-d-Aspartate Receptor Channels Inferred from Single-channel Current Patterns

6 September 2017

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TASK, a human background K+ channel to sense external pH variations near physiological pH

6 September 2017

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Sites of alcohol and volatile anaesthetic action on GABA(A) and glycine receptors.

6 September 2017

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Different distribution of fluorinated anesthetics and nonanesthetics in model membrane: a 19F NMR study

6 September 2017

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The lateral pressure profile in membranes: a physical mechanism of general anesthesia

6 September 2017

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Volatile general anaesthetic actions on recombinant nACh alpha 7, 5-HT3 and chimeric nACh alpha 7-5-HT3 receptors expressed in Xenopus oocytes

6 September 2017

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Cloning, functional expression and brain localization of a novel unconventional outward rectifier K+ channel

6 September 2017

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The human glycine receptor beta subunit: primary structure, functional characterisation and chromosomal localisation of the human and murine genes

6 September 2017

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Effects of halothane and propofol on purified brain protein kinase C activation.

6 September 2017

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Stereoselective and non-stereoselective actions of isoflurane on the GABAA receptor

6 September 2017

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Structural conservation of ion conduction pathways in K channels and glutamate receptors

6 September 2017

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Can the stereoselective effects of the anesthetic isoflurane be accounted for by lipid solubility?

6 September 2017

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Structural analysis of mouse glycine receptor alpha subunit genes. Identification and chromosomal localization of a novel variant

6 September 2017

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Do general anaesthetics act by competitive binding to specific receptors?

6 September 2017

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The pressure reversal of general anesthesia and the critical volume hypothesis

6 September 2017

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The effects of anaesthetics and high pressure on the responses of the rat superior cervical ganglion in vitro

6 September 2017

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6 September 2017

Pharmacology of ethanol

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400 MHz two-dimensional nuclear Overhauser spectroscopy on anesthetic interaction with lipid bilayer

6 September 2017

1 reference

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The actions of propofol on inhibitory amino acid receptors of bovine adrenomedullary chromaffin cells and rodent central neurones

6 September 2017

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The antagonistic effect of an inhalation anesthetic and high pressure on the phase diagram of mixed dipalmitoyl-dimyristoylphosphatidylcholine bilayers

6 September 2017

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Inverse effects on gating and modulation caused by a mutation in the M2-M3 Linker of the GABA(A) receptor gamma subunit

6 September 2017

1 reference

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Determinants of the anesthetic sensitivity of two-pore domain acid-sensitive potassium channels: molecular cloning of an anesthetic-activated potassium channel from Lymnaea stagnalis

14 September 2017

1 reference

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Identification of structures within GABAA receptor alpha subunits that regulate the agonist action of pentobarbital

14 September 2017

1 reference

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Transmembrane residues define the action of isoflurane at the GABAA receptor alpha-3 subunit.

14 September 2017

1 reference

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Isoflurane modulation of neuronal nicotinic acetylcholine receptors expressed in human embryonic kidney cells.

14 September 2017

1 reference

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Activation of α2B-Adrenoceptors Mediates the Cardiovascular Effects of Etomidate

14 September 2017

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Species variation and the mechanism of pressure–anaesthetic interactions

14 September 2017

1 reference

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Effects of high pressure on the central nervous system

14 September 2017

1 reference

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Pressure reversal of narcosis produced by anaesthetics, narcotics and tranquillisers

14 September 2017

1 reference

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Halothane binds in the adenine-specific niche of crystalline adenylate kinase

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989583

Effects of pressure and anesthetics on conduction and synaptic transmission

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989583

The influence of 1-alkanols and external pressure on the lateral pressure profiles of lipid bilayers.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989583

Evidence for a common binding cavity for three general anesthetics within the GABAA receptor.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989583

Mutant human alpha(1)beta(1)(T262Q) GABA(A) receptors are directly activated but not modulated by pentobarbital

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989583

Enhancement of Glycine Receptor Function by Ethanol Is Inversely Correlated with Molecular Volume at Position α267

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989583

Pressure antagonism of anaesthetic-induced conduction failure in frog peripheral nerve

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989583

Movement suppression during anesthesia: neural projections from the mesopontine tegmentum to areas involved in motor control

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989583

Sedation and anesthesia mediated by distinct GABA(A) receptor isoforms.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989583

GABA(A) receptors: immunocytochemical distribution of 13 subunits in the adult rat brain.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989583

A single glycine residue at the entrance to the first membrane-spanning domain of the gamma-aminobutyric acid type A receptor beta(2) subunit affects allosteric sensitivity to GABA and anesthetics

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989583

Evidence for a Tetrameric Structure of Recombinant NMDA Receptors

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989583

Interaction of i.v. anaesthetic agents with 5-HT3 receptors.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989583

Volatile anesthetics and glutamate activation of N-methyl-D-aspartate receptors

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989583

Quaternary structure of the native GABAA receptor determined by electron microscopic image analysis.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989583

Effects of volatile anesthetics on the kinetics of inhibitory postsynaptic currents in cultured rat hippocampal neurons

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989583

Binding of xenon to sperm whale myoglobin.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989583

The hyperpolarization of spinal motoneurones by glycine and related amino acids

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989583

Interaction between halothane and hydrostatic pressure.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989583

Pressure reversal of anaesthesia.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989583

Pressure reversal of inhalation anesthetic-induced disorder in spin-labeled phospholipid vesicles.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989583

The effect of two inhalation anesthetics on the order of spin-labeled phospholipid vesicles.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989583

Isoflurane effects in rat hippocampal cortex: a quantitative evaluation of different cellular sites of action

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989583

Isoflurane hyperpolarizes neurones in rat and human cerebral cortex

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989583

Volatile general anaesthetics activate a novel neuronal K+ current

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989583

Halothane-induced hyperpolarization and depression of postsynaptic potentials of guinea pig thalamic neurons in vitro

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989583

Isoflurane anesthesia is stereoselective

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989583

Neuromuscular function at hyperbaric pressures: pressure-anesthetic interactions

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989583

In-plane and out-of-plane infrared difference spectroscopy unravels tilting of helices and structural changes in a membrane protein upon substrate binding

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989583

A transmembrane residue influences the interaction of propofol with the strychnine-sensitive glycine alpha1 and alpha1beta receptor

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989583

Guide to Receptors and Channels (GRAC), 3rd edition

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989583

Influence of ethanol on lipid membranes: from lateral pressure profiles to dynamics and partitioning

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989583

A conserved tyrosine in the beta2 subunit M4 segment is a determinant of gamma-aminobutyric acid type A receptor sensitivity to propofol

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989583

Coarse graining of nonbonded degrees of freedom

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989583

Thalamic microinjection of nicotine reverses sevoflurane-induced loss of righting reflex in the rat.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989583

Exploring ligand recognition and ion flow in comparative models of the human GABA type A receptor

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989583

Effect of isoflurane and other potent inhaled anesthetics on minimum alveolar concentration, learning, and the righting reflex in mice engineered to express alpha1 gamma-aminobutyric acid type A receptors unresponsive to isoflurane

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989583

Identification of a GABAA receptor anesthetic binding site at subunit interfaces by photolabeling with an etomidate analog.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989583

Projections from the mesopontine tegmental anesthesia area to regions involved in pain modulation

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989583

Dual actions of enflurane on postsynaptic currents abolished by the gamma-aminobutyric acid type A receptor beta3(N265M) point mutation

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989583

Local and global ligand-induced changes in the structure of the GABA(A) receptor

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989583

Differential modulation of human N-methyl-D-aspartate receptors by structurally diverse general anesthetics

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989583

Alpha5GABAA receptors mediate the amnestic but not sedative-hypnotic effects of the general anesthetic etomidate.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989583

Charged residues in the alpha1 and beta2 pre-M1 regions involved in GABAA receptor activation.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989583

Limbic system participates in mediating the effects of general anesthetics

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989583

Neocortex is the major target of sedative concentrations of volatile anaesthetics: strong depression of firing rates and increase of GABAA receptor-mediated inhibition

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989583

Potent activation of the human tandem pore domain K channel TRESK with clinical concentrations of volatile anesthetics

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989583

Hydrostatic pressure reversal of narcosis in tadpoles.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989583

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989583

Major role for tonic GABAA conductances in anesthetic suppression of intrinsic neuronal excitability

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989583

Neurotransmission in central cardiovascular control: 10 suggestions for microinjections

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989583

Activity of narcotized amphibian larvae under hydrostatic pressure.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989583

Defining the propofol binding site location on the GABAA receptor

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989583

The actions of sevoflurane and desflurane on the gamma-aminobutyric acid receptor type A: effects of TM2 mutations in the alpha and beta subunits

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989583

2-(3-Methyl-3H-diaziren-3-yl)ethyl 1-(1-phenylethyl)-1H-imidazole-5-carboxylate: a derivative of the stereoselective general anesthetic etomidate for photolabeling ligand-gated ion channels

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989583

Effects of halothane and propofol on excitatory and inhibitory synaptic transmission in rat cortical neurons

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989583

Anesthetic and ethanol effects on spontaneously opening glycine receptor channels

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989583

The sedative component of anesthesia is mediated by GABA(A) receptors in an endogenous sleep pathway

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989583

Halogenated diazirines as photolabel mimics of the inhaled haloalkane anesthetics

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989583

The septohippocampal system participates in general anesthesia.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989583

Antagonism of inhalant and volatile anesthetic enhancement of glycine receptor function

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989583

Modulation of NMDA receptor function by ketamine and magnesium. Part II: interactions with volatile anesthetics

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989583

Protein mobility and GABA-induced conformational changes in GABA(A) receptor pore-lining M2 segment

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989583

Identification of sites of incorporation in the nicotinic acetylcholine receptor of a photoactivatible general anesthetic

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989583

Contrasting synaptic actions of the inhalational general anesthetics isoflurane and xenon

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989583

Sensory thresholds and the antinociceptive effects of GABA receptor agonists in mice lacking the beta3 subunit of the GABA(A) receptor.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989583

Amino acid volume and hydropathy of a transmembrane site determine glycine and anesthetic sensitivity of glycine receptors

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989583

Complementary regulation of anaesthetic activation of human (alpha6beta3gamma2L) and Drosophila (RDL) GABA receptors by a single amino acid residue

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989583

How does xenon produce anaesthesia?

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989583

Propofol and other intravenous anesthetics have sites of action on the gamma-aminobutyric acid type A receptor distinct from that for isoflurane.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989583

Distinct Loci Mediate the Direct and Indirect Actions of the Anesthetic Etomidate at GABAA Receptors

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989583

Gene knockout of the alpha6 subunit of the gamma-aminobutyric acid type A receptor: lack of effect on responses to ethanol, pentobarbital, and general anesthetics

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989583

Modulation of cardiac calcium channels by propofol

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989583

A pH-sensitive yeast outward rectifier K+ channel with two pore domains and novel gating properties

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989583

Stereospecific actions of the inhalation anesthetic isoflurane at the GABAA receptor complex

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989583

Propofol modulates activation and desensitization of GABAA receptors in cultured murine hippocampal neurons.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989583

The stereospecific effects of isoflurane isomers in vivo

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989583

Evidence for direct actions of general anesthetics on an ion channel protein. A new look at a unified mechanism of action.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989583

A discrete site for general anesthetics on a postsynaptic receptor.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989583

General anesthetics hyperpolarize neurons in the vertebrate central nervous system

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989583

Anesthetic antagonism of the effects of high hydrostatic pressure on locomotory activity of the brine shrimp Artemia

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989583

The general anesthetic potency of propofol and its dependence on hydrostatic pressure.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989583

Determination of NMDA NR1 subunit copy number in recombinant NMDA receptors

1 September 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2010.00891.X

Role of sterol type on lateral pressure profiles of lipid membranes affecting membrane protein functionality: Comparison between cholesterol, desmosterol, 7-dehydrocholesterol and ketosterol

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20735416

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Sensing isothermal changes in the lateral pressure in model membranes using di-pyrenyl phosphatidylcholine

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20735416

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Inhibition of Spinal Neurones by Glycine

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20735416

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Evidence for the involvement of non-androgenic testicular factors in the regulation of hypothalamic somatostatin and GHRH mRNA levels

1 reference

https://api.crossref.org/works/10.1111/J.1476-5381.2010.00891.X

Analysis of protein structure in intact cells: crosslinking in vivo between introduced cysteines in the transmembrane domain of a bacterial chemoreceptor

22 June 2024

1 reference

https://api.crossref.org/works/10.1111/J.1476-5381.2010.00891.X

Zur Theorie der Alkoholnarkose

22 June 2024

series ordinal

102

1 reference

https://api.crossref.org/works/10.1111/J.1476-5381.2010.00891.X

Some Physical Mechanisms in Narcosis

22 June 2024

series ordinal

108

1 reference

https://api.crossref.org/works/10.1111/J.1476-5381.2010.00891.X

22 June 2024

Identifiers

1 reference

23 August 2017

1 reference

23 August 2017

1 reference