Endogenous neurosteroids regulate GABAA receptors through two discrete transmembrane sites (Q34582058)

3 August 2017

title

Endogenous neurosteroids regulate GABAA receptors through two discrete transmembrane sites (English)

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3 August 2017

main subject

transmembrane protein

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Trevor G Smart

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3 August 2017

Megan E Wilkins

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3 August 2017

Alastair M Hosie

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3 August 2017

Helena M A da Silva

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3 August 2017

language of work or name

English

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publication date

15 November 2006

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3 August 2017

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3 August 2017

volume

444

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3 August 2017

issue

7118

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3 August 2017

page(s)

486-489

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Neurosteroids: endogenous regulators of the GABA(A) receptor

3 August 2017

cites work

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Neuroactive steroids reduce neuronal excitability by selectively enhancing tonic inhibition mediated by delta subunit-containing GABAA receptors

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Steroid hormone metabolites are barbiturate-like modulators of the GABA receptor

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Neurosteroids act on the GABA(A) receptor at sites on the N-terminal side of the middle of TM2.

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7 January 2021

Neurosteroid access to the GABAA receptor

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Identifiers

DOI

10.1038/NATURE05324

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Dimensions Publication ID

3 August 2017

1046200213

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