Phosphoinositide 3-kinases and their role in inflammation: potential clinical targets in atherosclerosis? (Q37461480)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19397491%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

review article

1 reference

title

Phosphoinositide 3-kinases and their role in inflammation: potential clinical targets in atherosclerosis? (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19397491%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

0 references

1 reference

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19397491%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

Anne Fougerat

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19397491%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

Stéphanie Gayral

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19397491%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

Nicole Malet

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19397491%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

Fabienne Briand-Mesange

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19397491%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

Monique Breton-Douillon

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19397491%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

language of work or name

English

0 references

publication date

1 May 2009

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19397491%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19397491%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

volume

116

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19397491%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

issue

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19397491%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

page(s)

791-804

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19397491%20AND%20SRC:MED&resulttype=core&format=json

Cell biology of atherosclerosis

26 January 2020

cites work

1 reference

https://api.crossref.org/works/10.1042%2FCS20080549

Atherosclerosis — An Inflammatory Disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20080549

Inflammation in atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20080549

Innate and adaptive immunity in the pathogenesis of atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20080549

Multiple role of reactive oxygen species in the arterial wall.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20080549

Protective role of CXC receptor 4/CXC ligand 12 unveils the importance of neutrophils in atherosclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20080549

Mouse models for atherosclerosis and pharmaceutical modifiers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20080549

Decreased lesion formation in CCR2-/- mice reveals a role for chemokines in the initiation of atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20080549

Decreased atherosclerosis in mice deficient in both macrophage colony-stimulating factor (op) and apolipoprotein E

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20080549

Lymphocytes are important in early atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20080549

The immune response in atherosclerosis: a double-edged sword

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20080549

IFN-gamma potentiates atherosclerosis in ApoE knock-out mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20080549

IL-10: the master regulator of immunity to infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20080549

Regulatory T-cell immunity in atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20080549

Mast cells: multipotent local effector cells in atherothrombosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20080549

Localization of apoptotic macrophages at the site of plaque rupture in sudden coronary death

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20080549

Human vascular smooth muscle cell-monocyte interactions and metalloproteinase secretion in culture.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20080549

Cytokine-stimulated human vascular smooth muscle cells synthesize a complement of enzymes required for extracellular matrix digestion

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20080549

Mast cells in vulnerable coronary plaques: potential mechanisms linking mast cell activation to plaque erosion and rupture

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20080549

Synovial procollagenase activation by human mast cell tryptase dependence upon matrix metalloproteinase 3 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20080549

Mast cell chymase inhibits smooth muscle cell growth and collagen expression in vitro: transforming growth factor-beta1-dependent and -independent effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20080549

Regulation of smooth muscle cell growth, function and death in vitro by activated mast cells--a potential mechanism for the weakening and rupture of atherosclerotic plaques

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20080549

Synthesis and function of 3-phosphorylated inositol lipids

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20080549

p84, a new Gbetagamma-activated regulatory subunit of the type IB phosphoinositide 3-kinase p110gamma

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20080549

Characterization of p87PIKAP, a novel regulatory subunit of phosphoinositide 3-kinase gamma that is highly expressed in heart and interacts with PDE3B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20080549

A critical role for phosphoinositide 3-kinase upstream of Gab1 and SHP2 in the activation of ras and mitogen-activated protein kinases by epidermal growth factor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20080549

Phosphatidylinositol 3′-Kinase-independent p70 S6 Kinase Activation by Fibroblast Growth Factor Receptor-1 Is Important for Proliferation but Not Differentiation of Endothelial Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20080549

Growth-hormone signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20080549

Growth hormone, interferon-gamma, and leukemia inhibitory factor promoted tyrosyl phosphorylation of insulin receptor substrate-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20080549

Phosphoinositide 3-kinase signalling--which way to target?

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20080549

Phosphoinositide 3-kinase and its targets in B-cell and T-cell signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20080549

The p110beta isoform of phosphoinositide 3-kinase signals downstream of G protein-coupled receptors and is functionally redundant with p110gamma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20080549

Phosphoinositide 3-kinase p110beta activity: key role in metabolism and mammary gland cancer but not development

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20080549

Phosphatidylinositol 3-kinase encoded by yeast VPS34 gene essential for protein sorting

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20080549

Proliferative defect and embryonic lethality in mice homozygous for a deletion in the p110alpha subunit of phosphoinositide 3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20080549

Central role for G protein-coupled phosphoinositide 3-kinase gamma in inflammation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20080549

Function of PI3Kgamma in thymocyte development, T cell activation, and neutrophil migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20080549

Roles of PLC-beta2 and -beta3 and PI3Kgamma in chemoattractant-mediated signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20080549

Distinct PI(3)Ks mediate mitogenic signalling and cell migration in macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20080549

Essential role of phosphoinositide 3-kinase delta in neutrophil directional movement

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20080549

Phosphoinositide 3-kinase gamma inhibition plays a crucial role in early steps of inflammation by blocking neutrophil recruitment

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20080549

The role of endothelial PI3Kgamma activity in neutrophil trafficking

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20080549

Differential requirements for DOCK2 and phosphoinositide-3-kinase gamma during T and B lymphocyte homing

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20080549

Cutting edge: differential roles for phosphoinositide 3-kinases, p110gamma and p110delta, in lymphocyte chemotaxis and homing

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20080549

A central role for DOCK2 during interstitial lymphocyte motility and sphingosine-1-phosphate-mediated egress

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20080549

Class IB-phosphatidylinositol 3-kinase (PI3K) deficiency ameliorates IA-PI3K-induced systemic lupus but not T cell invasion

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20080549

Phosphatidylinositol-3-OH kinase and nutrient-sensing mTOR pathways control T lymphocyte trafficking

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20080549

Phosphoinositide 3-kinase gamma participates in T cell receptor-induced T cell activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20080549

Cutting edge: T cell development requires the combined activities of the p110gamma and p110delta catalytic isoforms of phosphatidylinositol 3-kinase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20080549

Regulation and termination of NADPH oxidase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20080549

Sequential activation of class IB and class IA PI3K is important for the primed respiratory burst of human but not murine neutrophils

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20080549

Toll-like receptor signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20080549

PI3K and negative regulation of TLR signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20080549

The phosphatidylinositol 3-kinase-Akt pathway limits lipopolysaccharide activation of signaling pathways and expression of inflammatory mediators in human monocytic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20080549

Chronic estradiol administration in vivo promotes the proinflammatory response of macrophages to TLR4 activation: involvement of the phosphatidylinositol 3-kinase pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20080549

Opposite effects of wortmannin and 2-(4-morpholinyl)-8-phenyl-1(4H)-benzopyran-4-one hydrochloride on toll-like receptor-mediated nitric oxide production: negative regulation of nuclear factor-{kappa}B by phosphoinositide 3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20080549

Essential role for Gab2 in the allergic response

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20080549

Modulation of the Fcepsilon receptor I signaling by tyrosine kinase inhibitors: search for therapeutic targets of inflammatory and allergy diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20080549

Essential role for the p110delta phosphoinositide 3-kinase in the allergic response

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20080549

Phosphoinositide 3-kinase gamma is an essential amplifier of mast cell function

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20080549

Inhibition of phosphoinositide 3-kinase delta attenuates allergic airway inflammation and hyperresponsiveness in murine asthma model

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20080549

Isoform-specific functions of phosphoinositide 3-kinases: p110 delta but not p110 gamma promotes optimal allergic responses in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20080549

Phosphoinositide-3 kinases critically regulate the recruitment and survival of eosinophils in vivo: importance for the resolution of allergic inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20080549

Functional phenotype of phosphoinositide 3-kinase p85alpha-null platelets characterized by an impaired response to GP VI stimulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20080549

Increased insulin sensitivity and hypoglycaemia in mice lacking the p85 alpha subunit of phosphoinositide 3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20080549

Xid-like immunodeficiency in mice with disruption of the p85alpha subunit of phosphoinositide 3-kinase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20080549

Role of the p110delta PI 3-kinase in integrin and ITAM receptor signalling in platelets

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20080549

PI 3-kinase p110beta: a new target for antithrombotic therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20080549

The relative role of PLCbeta and PI3Kgamma in platelet activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20080549

Anti-inflammatory drugs and atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20080549

Statin therapy, LDL cholesterol, C-reactive protein, and coronary artery disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20080549

C-reactive protein levels and outcomes after statin therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20080549

Statins as immunomodulatory agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20080549

Low dose oral cannabinoid therapy reduces progression of atherosclerosis in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20080549

Targeting phosphoinositide 3-kinase: moving towards therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20080549

Role of PlGF in the intra- and intermolecular cross talk between the VEGF receptors Flt1 and Flk1

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20080549

PI3Kgamma inhibition: towards an 'aspirin of the 21st century'?

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20080549

Deletion of the phosphoinositide 3-kinase p110gamma gene attenuates murine atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20080549

Genetic and pharmacological targeting of phosphoinositide 3-kinase-gamma reduces atherosclerosis and favors plaque stability by modulating inflammatory processes

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20080549

Protection from angiotensin II-mediated vasculotoxic and hypertensive response in mice lacking PI3Kgamma

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20080549

Regulation of myocardial contractility and cell size by distinct PI3K-PTEN signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20080549

Phosphoinositide 3-kinase gamma/delta inhibition limits infarct size after myocardial ischemia/reperfusion injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20080549

Isoform-selective PI3K inhibitors as novel therapeutics for the treatment of acute myocardial infarction

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20080549

PI3Kγ Modulates the Cardiac Response to Chronic Pressure Overload by Distinct Kinase-Dependent and -Independent Effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20080549

Protective Role of Interleukin-10 in Atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20080549

Natural regulatory T cells control the development of atherosclerosis in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20080549