Shared functional defect in IP₃R-mediated calcium signaling in diverse monogenic autism syndromes (Q37347754)

19 August 2017

Shared functional defect in IP₃R-mediated calcium signaling in diverse monogenic autism syndromes (English)

1 reference

19 August 2017

0 references

G Schmunk

1 reference

19 August 2017

B J Boubion

1 reference

19 August 2017

I F Smith

1 reference

19 August 2017

I Parker

1 reference

19 August 2017

J J Gargus

1 reference

19 August 2017

22 September 2015

1 reference

19 August 2017

Translational Psychiatry

1 reference

19 August 2017

1 reference

19 August 2017

e643

1 reference

Creative Commons Attribution 4.0 International

19 August 2017

start time

1 September 2015

1 reference

April 2022 Public Data File from Crossref

copyrighted

0 references

describes a project that uses

ImageQuant

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC5068815/fullTextXML

inferred from PubMed Central ID database lookup

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC5068815/fullTextXML

inferred from PubMed Central ID database lookup

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6 September 2017

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Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis

6 September 2017

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6 September 2017

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6 September 2017

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The probability of triggering calcium puffs is linearly related to the number of inositol trisphosphate receptors in a cluster.

6 September 2017

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Expression profiling of autism candidate genes during human brain development implicates central immune signaling pathways

6 September 2017

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Genetic Heritability and Shared Environmental Factors Among Twin Pairs With Autism

6 September 2017

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Abnormal cell properties and down-regulated FAK-Src complex signaling in B lymphoblasts of autistic subjects

6 September 2017

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Rare de novo variants associated with autism implicate a large functional network of genes involved in formation and function of synapses

6 September 2017

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Role of inositol 1,4,5-trisphosphate receptors in pathogenesis of Huntington's disease and spinocerebellar ataxias

6 September 2017

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Etiological heterogeneity in autism spectrum disorders: more than 100 genetic and genomic disorders and still counting

6 September 2017

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6 September 2017

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Fragile X: leading the way for targeted treatments in autism

6 September 2017

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Group 1 mGluR-dependent synaptic long-term depression: mechanisms and implications for circuitry and disease

6 September 2017

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6 September 2017

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6 September 2017

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Metabotropic glutamate receptor-mediated use-dependent down-regulation of synaptic excitability involves the fragile X mental retardation protein

6 September 2017

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Localization of puff sites adjacent to the plasma membrane: functional and spatial characterization of Ca2+ signaling in SH-SY5Y cells utilizing membrane-permeant caged IP3.

6 September 2017

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Order-dependent coincidence detection in cerebellar Purkinje neurons at the inositol trisphosphate receptor

6 September 2017

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A kinetic model of single and clustered IP3 receptors in the absence of Ca2+ feedback

6 September 2017

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Regulation of autophagy by the inositol trisphosphate receptor

6 September 2017

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The mGluR theory of fragile X mental retardation

6 September 2017

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Inositol 1,4,5-trisphosphate receptors as signal integrators

6 September 2017

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Calcium dynamics and endoplasmic reticular function in the regulation of protein synthesis: implications for cell growth and adaptability

6 September 2017

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Stores not just for storage. intracellular calcium release and synaptic plasticity

6 September 2017

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The Screening and Diagnosis of Autistic Spectrum Disorders

6 September 2017

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Isolation of a novel potassium channel gene hSKCa3 containing a polymorphic CAG repeat: a candidate for schizophrenia and bipolar disorder?

6 September 2017

1 reference

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Elementary and global aspects of calcium signalling

6 September 2017

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Small-conductance, calcium-activated potassium channels from mammalian brain

6 September 2017

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Inositol trisphosphate and calcium signalling

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5068815

Internal Ca2+ mobilization is altered in fibroblasts from patients with Alzheimer disease

6 September 2017

1 reference

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Quantal puffs of intracellular Ca2+ evoked by inositol trisphosphate in Xenopus oocytes

6 September 2017

1 reference

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A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

6 September 2017

1 reference

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Essential regulation of cell bioenergetics by constitutive InsP3 receptor Ca2+ transfer to mitochondria.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5068815

The inositol 1,4,5-trisphosphate receptor regulates autophagy through its interaction with Beclin 1.

14 September 2017

1 reference

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Cell-permeant caged InsP3 ester shows that Ca2+ spike frequency can optimize gene expression

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5068815

Elementary events of InsP3-induced Ca2+ liberation in Xenopus oocytes: hot spots, puffs and blips

28 September 2017

1 reference

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A hierarchical concept of cellular and subcellular Ca(2+)-signalling

28 September 2017

1 reference

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Loss of Tsc1 in vivo impairs hippocampal mGluR-LTD and increases excitatory synaptic function

28 September 2017

1 reference

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Type 1 inositol 1,4,5-trisphosphate receptor is required for induction of long-term depression in cerebellar Purkinje neurons.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5068815

Inositol trisphosphate-mediated Ca2+ influx into Xenopus oocytes triggers Ca2+ liberation from intracellular stores

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5068815

Extracellular nucleotides stimulate receptor-mediated calcium mobilization and inositol phosphate production in human fibroblasts

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5068815

Generation of calcium oscillations in fibroblasts by positive feedback between calcium and IP3.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5068815

Potentiation of neurotransmitter release coincides with potentiation of phosphatidyl inositol turnover. A possible in vitro model for long term potentiation

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5068815

Inositol phosphates and intracellular calcium after bradykinin stimulation in fibroblasts from young, normal aged and Alzheimer donors

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5068815

Bell-shaped calcium-response curves of Ins(1,4,5)P3- and calcium-gated channels from endoplasmic reticulum of cerebellum

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5068815

Altered calcium homeostasis in autism-spectrum disorders: evidence from biochemical and genetic studies of the mitochondrial aspartate/glutamate carrier AGC1.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5068815

Enhanced caffeine-induced Ca2+ release in the 3xTg-AD mouse model of Alzheimer's disease

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5068815

Dysregulated IP3 signaling in cortical neurons of knock-in mice expressing an Alzheimer's-linked mutation in presenilin1 results in exaggerated Ca2+ signals and altered membrane excitability.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5068815

Buffer kinetics shape the spatiotemporal patterns of IP3-evoked Ca2+ signals

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5068815

Ca2+ signaling in mouse cortical neurons studied by two-photon imaging and photoreleased inositol triphosphate.

2 September 2018

1 reference

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D2 dopamine receptors in striatal medium spiny neurons reduce L-type Ca2+ currents and excitability via a novel PLC[beta]1-IP3-calcineurin-signaling cascade.

2 September 2018

1 reference

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In vivo regulation of axon extension and pathfinding by growth-cone calcium transients

2 September 2018

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Enhancement of neurotransmitter release induced by brain-derived neurotrophic factor in cultured hippocampal neurons.

2 September 2018

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Inositol trisphosphate mediates a RAS-independent response to LET-23 receptor tyrosine kinase activation in C. elegans

2 September 2018

1 reference

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Pyrrolidine dithiocarbamate attenuates surgery-induced neuroinflammation and cognitive dysfunction possibly via inhibition of nuclear factor κB

2 September 2018

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Crossref

https://api.crossref.org/works/10.1038%2FTP.2015.123

Human primary fibroblasts in vitro express a purinergic P2X7 receptor coupled to ion fluxes, microvesicle formation and IL-6 release

21 January 2018

1 reference

12 December 2020

Mechanosensitive ATP release from hemichannels and Ca²⁺ influx through TRPC6 accelerate wound closure in keratinocytes

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12 December 2020

Synergistic release of Ca2+ from IP3-sensitive stores evoked by synaptic activation of mGluRs paired with backpropagating action potentials

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12 December 2020

Metabotropic glutamate receptors regulate hippocampal CA1 pyramidal neuron excitability via Ca²⁺ wave-dependent activation of SK and TRPC channels

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12 December 2020

Skin biopsy: a useful tool in the diagnosis of lysosomal storage diseases

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12 December 2020

[Normal skin biopsy as a tool for extra-cutaneous disorders]

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12 December 2020

Identifiers

DOI

10.1038/TP.2015.123

1 reference

19 August 2017

1 reference

19 August 2017

PubMed publication ID

26393489

1 reference