Dysregulated IP3 signaling in cortical neurons of knock-in mice expressing an Alzheimer's-linked mutation in presenilin1 results in exaggerated Ca2+ signals and altered membrane excitability. (Q44728737)

From Wikidata

Jump to navigation Jump to search

scientific article

Language	Label	Description	Also known as
English	Dysregulated IP3 signaling in cortical neurons of knock-in mice expressing an Alzheimer's-linked mutation in presenilin1 results in exaggerated Ca2+ signals and altered membrane excitability.	scientific article

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

5 December 2017

Dysregulated IP3 signaling in cortical neurons of knock-in mice expressing an Alzheimer's-linked mutation in presenilin1 results in exaggerated Ca2+ signals and altered membrane excitability (English)

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6729995&resulttype=core&format=json

12 May 2020

Alzheimer's disease

0 references

author name string

Grace E Stutzmann

1

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6729995&resulttype=core&format=json

12 May 2020

Antonella Caccamo

2

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6729995&resulttype=core&format=json

12 May 2020

Frank M LaFerla

3

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6729995&resulttype=core&format=json

12 May 2020

Ian Parker

4

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6729995&resulttype=core&format=json

12 May 2020

language of work or name

0 references

publication date

1 January 2004

1 reference

Europe PubMed Central

PubMed publication ID

5 December 2017

Journal of Neuroscience

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6729995&resulttype=core&format=json

12 May 2020

24

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6729995&resulttype=core&format=json

12 May 2020

2

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6729995&resulttype=core&format=json

12 May 2020

508-513

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6729995&resulttype=core&format=json

12 May 2020

Increased vulnerability of hippocampal neurons from presenilin-1 mutant knock-in mice to amyloid beta-peptide toxicity: central roles of superoxide production and caspase activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/14724250

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alzheimer's presenilin-1 mutation potentiates inositol 1,4,5-trisphosphate-mediated calcium signaling in Xenopus oocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/14724250

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synaptic transmission and hippocampal long-term potentiation in transgenic mice expressing FAD-linked presenilin 1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14724250

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cellular distribution of the calcium-binding proteins parvalbumin, calbindin, and calretinin in the neocortex of mammals: phylogenetic and developmental patterns

1 reference

https://pubmed.ncbi.nlm.nih.gov/14724250

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Calcium signaling in the ER: its role in neuronal plasticity and neurodegenerative disorders

1 reference

https://pubmed.ncbi.nlm.nih.gov/14724250

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional phenotype in transgenic mice expressing mutant human presenilin-1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14724250

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Capacitative calcium entry deficits and elevated luminal calcium content in mutant presenilin-1 knockin mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/14724250

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synaptic plasticity in hippocampal CA1 neurons of mice lacking type 1 inositol-1,4,5-trisphosphate receptors.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14724250

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Presenilin-mediated modulation of capacitative calcium entry

1 reference

https://pubmed.ncbi.nlm.nih.gov/14724250

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Presenilin-1 regulates the neuronal threshold to excitotoxicity both physiologically and pathologically

1 reference

https://pubmed.ncbi.nlm.nih.gov/14724250

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Local calcium release in dendritic spines required for long-term synaptic depression

1 reference

https://pubmed.ncbi.nlm.nih.gov/14724250

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Calcium stores regulate the polarity and input specificity of synaptic modification

1 reference

https://pubmed.ncbi.nlm.nih.gov/14724250

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alzheimer's disease: genes, proteins, and therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/14724250

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanisms of Ca(2+)-dependent transcription

1 reference

https://pubmed.ncbi.nlm.nih.gov/14724250

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Construction of a two-photon microscope for video-rate Ca(2+) imaging

1 reference

https://pubmed.ncbi.nlm.nih.gov/14724250

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dysregulation of cellular calcium homeostasis in Alzheimer's disease: bad genes and bad habits

1 reference

https://pubmed.ncbi.nlm.nih.gov/14724250

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ca(2+) dynamics in the lumen of the endoplasmic reticulum in sensory neurons: direct visualization of Ca(2+)-induced Ca(2+) release triggered by physiological Ca(2+) entry

1 reference

https://pubmed.ncbi.nlm.nih.gov/14724250

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A distinct form of calcium release down-regulates membrane excitability in neocortical pyramidal cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14724250

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Age-related and laminar-specific dendritic changes in the medial frontal cortex of the rat.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14724250

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Calcium dyshomeostasis and intracellular signalling in Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/14724250

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Capacitive calcium entry is directly attenuated by mutant presenilin-1, independent of the expression of the amyloid precursor protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/14724250

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The endoplasmic reticulum: a multifunctional signaling organelle

1 reference

https://pubmed.ncbi.nlm.nih.gov/14724250

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Calcium leak from intracellular stores--the enigma of calcium signalling

1 reference

https://pubmed.ncbi.nlm.nih.gov/14724250

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ca2+ signaling in mouse cortical neurons studied by two-photon imaging and photoreleased inositol triphosphate.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14724250

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stereologic analysis of neurofibrillary tangle formation in prefrontal cortex area 9 in aging and Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/14724250

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Triple-transgenic model of Alzheimer's disease with plaques and tangles: intracellular Abeta and synaptic dysfunction

1 reference

https://pubmed.ncbi.nlm.nih.gov/14724250

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characteristics of membrane currents evoked by photoreleased inositol trisphosphate in Xenopus oocytes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14724250

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparative electrophysiology of pyramidal and sparsely spiny stellate neurons of the neocortex

1 reference

https://pubmed.ncbi.nlm.nih.gov/14724250

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anatomical correlates of the distribution of the pathological changes in the neocortex in Alzheimer disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/14724250

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ca(2+)-induced Ca2+ release and its activation in response to a single action potential in rabbit otic ganglion cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/14724250

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuronal Ca2+ stores: activation and function

1 reference

https://pubmed.ncbi.nlm.nih.gov/14724250

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cellular basis of working memory

1 reference

https://pubmed.ncbi.nlm.nih.gov/14724250

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Calcium hypothesis of Alzheimer's disease and brain aging.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14724250

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Internal Ca2+ mobilization is altered in fibroblasts from patients with Alzheimer disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/14724250

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutations of the presenilin I gene in families with early-onset Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/14724250

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ca(2+)-activated K+ currents in neurones: types, physiological roles and modulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/14724250

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Calcium responses in human fibroblasts: a diagnostic molecular profile for Alzheimer's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14724250

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The distribution of two calcium binding proteins, calbindin D-28K and parvalbumin, in the entorhinal cortex of the adult mouse

1 reference

https://pubmed.ncbi.nlm.nih.gov/14724250

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alzheimer's PS-1 mutation perturbs calcium homeostasis and sensitizes PC12 cells to death induced by amyloid beta-peptide.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14724250

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical and Molecular Analysis of Neurodegenerative Diseases

1 reference

https://pubmed.ncbi.nlm.nih.gov/14724250

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Release and sequestration of calcium by ryanodine‐sensitive stores in rat hippocampal neurones

1 reference

https://pubmed.ncbi.nlm.nih.gov/14724250

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selective representation of relevant information by neurons in the primate prefrontal cortex

1 reference

https://pubmed.ncbi.nlm.nih.gov/14724250

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuronal calcium signaling

1 reference

https://pubmed.ncbi.nlm.nih.gov/14724250

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Calsenilin: a calcium-binding protein that interacts with the presenilins and regulates the levels of a presenilin fragment

1 reference

https://pubmed.ncbi.nlm.nih.gov/14724250

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased vulnerability of hippocampal neurons to excitotoxic necrosis in presenilin-1 mutant knock-in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/14724250

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.4386-03.2004

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6729995&resulttype=core&format=json

12 May 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6729995&resulttype=core&format=json

12 May 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6729995&resulttype=core&format=json

12 May 2020

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q44728737&oldid=1989497574"