Acute neurodegeneration and the inflammasome: central processor for danger signals and the inflammatory response? (Q37062902)

18 August 2017

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title

Acute neurodegeneration and the inflammasome: central processor for danger signals and the inflammatory response? (English)

1 reference

18 August 2017

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1 reference

1 reference

George Trendelenburg

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author name string

George Trendelenburg

series ordinal

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18 August 2017

publication date

23 January 2008

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Journal of Cerebral Blood Flow & Metabolism

18 August 2017

published in

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18 August 2017

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18 August 2017

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18 August 2017

page(s)

867-881

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CDP-choline significantly restores phosphatidylcholine levels by differentially affecting phospholipase A2 and CTP: phosphocholine cytidylyltransferase after stroke

18 August 2017

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Identification of a key pathway required for the sterile inflammatory response triggered by dying cells

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The class B scavenger receptor CD36 mediates free radical production and tissue injury in cerebral ischemia.

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21 January 2018

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Cryopyrin/NALP3 binds ATP/dATP, is an ATPase, and requires ATP binding to mediate inflammatory signaling

21 January 2018

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"Eat me" and "don't eat me" signals govern the innate immune response and tissue repair in the CNS: emphasis on the critical role of the complement system

21 January 2018

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A randomised phase II study of interleukin-1 receptor antagonist in acute stroke patients

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Ischemic preconditioning increases antioxidants in the brain and peripheral organs after cerebral ischemia

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Pannexin-1-Mediated Recognition of Bacterial Molecules Activates the Cryopyrin Inflammasome Independent of Toll-like Receptor Signaling

21 January 2018

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Bacterial RNA and small antiviral compounds activate caspase-1 through cryopyrin/Nalp3

21 January 2018

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21 January 2018

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mRNA is an endogenous ligand for Toll-like receptor 3.

21 January 2018

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Inhibition of toll-like receptor and cytokine signaling--a unifying theme in ischemic tolerance

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Murine ortholog of ASC, a CARD-containing protein, self-associates and exhibits restricted distribution in developing mouse embryos

21 January 2018

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The danger model: a renewed sense of self

21 January 2018

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Friendly and dangerous signals: is the tissue in control?

21 January 2018

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A crucial function of SGT1 and HSP90 in inflammasome activity links mammalian and plant innate immune responses

21 January 2018

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Viruses selectively upregulate Toll-like receptors in the central nervous system

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Cytoplasmic flagellin activates caspase-1 and secretion of interleukin 1beta via Ipaf

21 January 2018

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NF-kappaB activation by the Toll-IL-1 receptor domain protein MyD88 adapter-like is regulated by caspase-1.

21 January 2018

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Expression and distribution of Toll-like receptors in the brain during murine neurocysticercosis

21 January 2018

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Critical role of toll-like receptors and nucleotide oligomerisation domain in the regulation of health and disease

21 January 2018

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21 January 2018

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Nucleotide-binding oligomerization domain-2 modulates specific TLR pathways for the induction of cytokine release

21 January 2018

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Tissue-specific mRNA expression profiles of human toll-like receptors and related genes

21 January 2018

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Cutting edge: CIAS1/cryopyrin/PYPAF1/NALP3/CATERPILLER 1.1 is an inducible inflammatory mediator with NF-kappa B suppressive properties

21 January 2018

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A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease

21 January 2018

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The inflammasome: first line of the immune response to cell stress

21 January 2018

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ASC is a Bax adaptor and regulates the p53-Bax mitochondrial apoptosis pathway

21 January 2018

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Cell wall-mediated neuronal damage in early sepsis

21 January 2018

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A novel pathway of HMGB1-mediated inflammatory cell recruitment that requires Mac-1-integrin

21 January 2018

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Distinct roles of TLR2 and the adaptor ASC in IL-1beta/IL-18 secretion in response to Listeria monocytogenes

21 January 2018

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The death domain superfamily in intracellular signaling of apoptosis and inflammation

21 January 2018

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RICK/RIP2 Mediates Innate Immune Responses Induced through Nod1 and Nod2 but Not TLRs

21 January 2018

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Involvement of toll-like receptors 2 and 4 in cellular activation by high mobility group box 1 protein

21 January 2018

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Activation of the NALP3 inflammasome is triggered by low intracellular potassium concentration

21 January 2018

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Neuroprotective actions of endogenous interleukin-1 receptor antagonist (IL-1ra) are mediated by glia.

21 January 2018

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Oxidative stress generated by hemorrhagic shock recruits Toll-like receptor 4 to the plasma membrane in macrophages

21 January 2018

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Identification of Ipaf, a human caspase-1-activating protein related to Apaf-1

21 January 2018

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Stroke-induced immunodeficiency promotes spontaneous bacterial infections and is mediated by sympathetic activation reversal by poststroke T helper cell type 1-like immunostimulation

21 January 2018

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The TLR-7 agonist, imiquimod, enhances dendritic cell survival and promotes tumor antigen-specific T cell priming: relation to central nervous system antitumor immunity

21 January 2018

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Interaction between pyrin and the apoptotic speck protein (ASC) modulates ASC-induced apoptosis

21 January 2018

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Toll-like receptors modulate adult hippocampal neurogenesis

21 January 2018

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Uric acid reduces brain damage and improves the benefits of rt-PA in a rat model of thromboembolic stroke

21 January 2018

1 reference

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A short isoform of NOD2/CARD15, NOD2-S, is an endogenous inhibitor of NOD2/receptor-interacting protein kinase 2-induced signaling pathways

21 January 2018

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Caspase-1 builds a new barrier to infection

21 January 2018

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Enhanced bacterial clearance and sepsis resistance in caspase-12-deficient mice

21 January 2018

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Release of chromatin protein HMGB1 by necrotic cells triggers inflammation

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Reduced ischemic brain injury in interleukin-1 beta converting enzyme-deficient mice

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Engagement of CD14 mediates the inflammatory potential of monosodium urate crystals.

21 January 2018

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21 January 2018

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Molecular identification of a danger signal that alerts the immune system to dying cells

21 January 2018

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ASC, which is composed of a PYD and a CARD, is up-regulated by inflammation and apoptosis in human neutrophils

21 January 2018

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A pilot study of IL-1 inhibition by anakinra in acute gout

21 January 2018

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21 January 2018

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Mechanisms of spreading depression and hypoxic spreading depression-like depolarization

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COPs and POPs: modulators of inflammasome activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

The PAAD/PYRIN-family protein ASC is a dual regulator of a conserved step in nuclear factor kappaB activation pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

The PAAD/PYRIN-only protein POP1/ASC2 is a modulator of ASC-mediated nuclear-factor-kappa B and pro-caspase-1 regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Preconditioning reprograms the response to ischemic injury and primes the emergence of unique endogenous neuroprotective phenotypes: a speculative synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Functional expression of NOD2, a novel pattern recognition receptor for bacterial motifs, in primary murine astrocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Toll-like receptors and tolerance to ischaemic injury in the brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Signalling pathways and molecular interactions of NOD1 and NOD2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

The inflammasome in pathogen recognition and inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Major role of HSP70 as a paracrine inducer of cytokine production in human oxidized LDL treated macrophages.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Autophagy and inflammatory cell death, partners of innate immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Pivotal role for neuronal Toll-like receptors in ischemic brain injury and functional deficits

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Fibronectin and laminin increase in the mouse brain after controlled cortical impact injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Cutting edge: ASC mediates the induction of multiple cytokines by Porphyromonas gingivalis via caspase-1-dependent and -independent pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Identification of CARDIAK, a RIP-like kinase that associates with caspase-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

A novel heterodimeric cysteine protease is required for interleukin-1 beta processing in monocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

CATERPILLERs, pyrin and hereditary immunological disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Neuroprotective role of astrocytes in cerebral ischemia: focus on ischemic preconditioning

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

The nuclear factor HMGB1 mediates hepatic injury after murine liver ischemia-reperfusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

HSP70 as endogenous stimulus of the Toll/interleukin-1 receptor signal pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Activation of complement in the central nervous system: roles in neurodegeneration and neuroprotection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Mrp8 and Mrp14 are endogenous activators of Toll-like receptor 4, promoting lethal, endotoxin-induced shock

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

SIGIRR, a negative regulator of Toll-like receptor-interleukin 1 receptor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Murine caspase-11, an ICE-interacting protease, is essential for the activation of ICE.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

PYNOD, a novel Apaf-1/CED4-like protein is an inhibitor of ASC and caspase-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

NOD2 is a negative regulator of Toll-like receptor 2-mediated T helper type 1 responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Serum urate as an independent predictor of poor outcome and future vascular events after acute stroke.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Fibronectin and neuroprotective effect of granulocyte colony-stimulating factor in focal cerebral ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Nod1, a CARD protein, enhances pro-interleukin-1beta processing through the interaction with pro-caspase-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

HMGB1 signals through toll-like receptor (TLR) 4 and TLR2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

The impact of endogenous triggers on trauma-associated inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Fundamental role of the Rip2/caspase-1 pathway in hypoxia and ischemia-induced neuronal cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Regulation of Toll-like receptor-mediated inflammatory response by complement in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Exposure to cell phone radiation up-regulates apoptosis genes in primary cultures of neurons and astrocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

TLR2 has a detrimental role in mouse transient focal cerebral ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Toll-like receptor 2 modulates left ventricular function following ischemia-reperfusion injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

High-Mobility Group Box 1 Activates Integrin-Dependent Homing of Endothelial Progenitor Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

Role of IL-1alpha and IL-1beta in ischemic brain damage.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

7 January 2021

TLRs, NLRs and RLRs: a trinity of pathogen sensors that co-operate in innate immunity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

7 January 2021

The role of the complement cascade in ischemia/reperfusion injury: implications for neuroprotection

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

7 January 2021

Toll-like receptors 2-deficient mice are protected against postischemic coronary endothelial dysfunction

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

7 January 2021

Regulation of astrocyte proliferation by FGF-2 and heparan sulfate in vivo

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

7 January 2021

Cutting edge: high-mobility group box 1 preconditioning protects against liver ischemia-reperfusion injury

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

7 January 2021

Xanthine and uric acid levels in rat brain following focal ischemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

7 January 2021

Expression of apoptosis-associated speck-like protein containing a caspase recruitment domain, a pyrin N-terminal homology domain-containing protein, in normal human tissues

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

7 January 2021

The role of the complement system in traumatic brain injury

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

7 January 2021

Expression of interleukin-6, c-fos, and zif268 mRNAs in rat ischemic cortex

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

7 January 2021

Formation of complement membrane attack complex in mammalian cerebral cortex evokes seizures and neurodegeneration.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600609

7 January 2021

Identifiers

DOI

10.1038/SJ.JCBFM.9600609

1 reference

18 August 2017

1 reference