Signalling pathways and molecular interactions of NOD1 and NOD2 (Q28298636)

NODs: intracellular proteins involved in inflammation and apoptosis

31 March 2020

1 reference

Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease

31 March 2020

1 reference

A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease

31 March 2020

1 reference

Association between a complex insertion/deletion polymorphism in NOD1 (CARD4) and susceptibility to inflammatory bowel disease

31 March 2020

1 reference

NOD1 variation, immunoglobulin E and asthma.

31 March 2020

1 reference

Nod1 responds to peptidoglycan delivered by the Helicobacter pylori cag pathogenicity island

31 March 2020

1 reference

CATERPILLER: a novel gene family important in immunity, cell death, and diseases

31 March 2020

1 reference

Nods, Nalps and Naip: intracellular regulators of bacterial-induced inflammation

31 March 2020

1 reference

Mutation of a new gene encoding a putative pyrin-like protein causes familial cold autoinflammatory syndrome and Muckle-Wells syndrome

31 March 2020

1 reference

Membrane recruitment of NOD2 in intestinal epithelial cells is essential for nuclear factor-{kappa}B activation in muramyl dipeptide recognition

31 March 2020

1 reference

Host recognition of bacterial muramyl dipeptide mediated through NOD2. Implications for Crohn's disease

31 March 2020

1 reference

An essential role for NOD1 in host recognition of bacterial peptidoglycan containing diaminopimelic acid

31 March 2020

1 reference

Nod1 detects a unique muropeptide from gram-negative bacterial peptidoglycan

31 March 2020

1 reference

Nod2 is a general sensor of peptidoglycan through muramyl dipeptide (MDP) detection

31 March 2020

1 reference

Induction of Nod2 in Myelomonocytic and Intestinal Epithelial Cells via Nuclear Factor-κB Activation

31 March 2020

1 reference

Nod2, a Nod1/Apaf-1 family member that is restricted to monocytes and activates NF-kappaB

31 March 2020

1 reference

CARD15/NOD2 functions as an antibacterial factor in human intestinal epithelial cells

31 March 2020

1 reference

Crohn's disease and the NOD2 gene: a role for paneth cells

31 March 2020

1 reference

Interferon-gamma augments CARD4/NOD1 gene and protein expression through interferon regulatory factor-1 in intestinal epithelial cells

31 March 2020

1 reference

Nod1 is an essential signal transducer in intestinal epithelial cells infected with bacteria that avoid recognition by toll-like receptors

31 March 2020

1 reference

Expression of NOD2 in Paneth cells: a possible link to Crohn's ileitis

31 March 2020

1 reference

TNF-alpha and IFN-gamma regulate the expression of the NOD2 (CARD15) gene in human intestinal epithelial cells.

31 March 2020

1 reference

IFN Regulatory Factor 3-Dependent Induction of Type I IFNs by Intracellular Bacteria Is Mediated by a TLR- and Nod2-Independent Mechanism

31 March 2020

1 reference

NOD-LRR proteins: role in host-microbial interactions and inflammatory disease

31 March 2020

1 reference

Role of Nod2 in the Response of Macrophages to Toll-Like Receptor Agonists

31 March 2020

1 reference

Comparison of biosynthesis and subcellular distribution of lysozyme and lysosomal enzymes in U937 monocytes.

31 March 2020

1 reference

Isolation of glucosaminyl-beta(1-4)-muramic acid and phosphoric acid ester of this disaccharide from acid hydrolysates of peptidoglycan of Bacillus cereus AHU 1356 cell walls

31 March 2020

1 reference

hPepT1 transports muramyl dipeptide, activating NF-kappaB and stimulating IL-8 secretion in human colonic Caco2/bbe cells

31 March 2020

1 reference

Leucine-rich repeats and pathogen recognition in Toll-like receptors.

31 March 2020

1 reference

Regulatory regions and critical residues of NOD2 involved in muramyl dipeptide recognition

31 March 2020

1 reference

Cytochrome c and dATP-mediated oligomerization of Apaf-1 is a prerequisite for procaspase-9 activation

31 March 2020

1 reference

Expression and functional analysis of Apaf-1 isoforms. Extra Wd-40 repeat is required for cytochrome c binding and regulated activation of procaspase-9

31 March 2020

1 reference

NOD2 is a negative regulator of Toll-like receptor 2-mediated T helper type 1 responses

31 March 2020

1 reference

RICK/Rip2/CARDIAK mediates signalling for receptors of the innate and adaptive immune systems

31 March 2020

1 reference

Nod1, an Apaf-1-like activator of caspase-9 and nuclear factor-kappaB

31 March 2020

1 reference

The Crohn's disease protein, NOD2, requires RIP2 in order to induce ubiquitinylation of a novel site on NEMO

31 March 2020

1 reference

Bcl10 activates the NF-kappaB pathway through ubiquitination of NEMO

31 March 2020

1 reference

GRIM-19 interacts with nucleotide oligomerization domain 2 and serves as downstream effector of anti-bacterial function in intestinal epithelial cells

31 March 2020

1 reference

Nod2-dependent regulation of innate and adaptive immunity in the intestinal tract

31 March 2020

1 reference

CARD4/Nod1 mediates NF-kappaB and JNK activation by invasive Shigella flexneri.

31 March 2020

1 reference

Heterotypic interactions among NACHT domains: implications for regulation of innate immune responses

31 March 2020

1 reference

Inflammatory caspases: linking an intracellular innate immune system to autoinflammatory diseases

31 March 2020

1 reference

CLAN, a novel human CED-4-like gene

31 March 2020

1 reference

Multiple roles of CLAN (caspase-associated recruitment domain, leucine-rich repeat, and NAIP CIIA HET-E, and TP1-containing protein) in the mammalian innate immune response

31 March 2020

1 reference

Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf

31 March 2020

1 reference

CARD6 is a modulator of NF-kappa B activation by Nod1- and Cardiak-mediated pathways

31 March 2020

1 reference

Identification of bacterial muramyl dipeptide as activator of the NALP3/cryopyrin inflammasome.

31 March 2020

1 reference

c-Rel regulates interleukin 12 p70 expression in CD8(+) dendritic cells by specifically inducing p35 gene transcription.

31 March 2020

1 reference

Selective requirement for c-Rel during IL-12 P40 gene induction in macrophages

31 March 2020

1 reference

How NOD-ing off leads to Crohn disease

31 March 2020

1 reference

Nod2 mutation in Crohn's disease potentiates NF-kappaB activity and IL-1beta processing

31 March 2020

1 reference

Toll-like receptor 2-dependent bacterial sensing does not occur via peptidoglycan recognition

31 March 2020

1 reference

Staphylococcus aureus peptidoglycan is a toll-like receptor 2 activator: a reevaluation

31 March 2020

1 reference

Muramyldipeptide and diaminopimelic acid-containing desmuramylpeptides in combination with chemically synthesized Toll-like receptor agonists synergistically induced production of interleukin-8 in a NOD2- and NOD1-dependent manner, respectively, in h

31 March 2020

1 reference

The origin of the synergistic effect of muramyl dipeptide with endotoxin and peptidoglycan

31 March 2020

1 reference

Synergy between TLR9 and NOD2 innate immune responses is lost in genetic Crohn's disease

31 March 2020

1 reference

Nucleotide-binding oligomerization domain-2 modulates specific TLR pathways for the induction of cytokine release

31 March 2020

1 reference

Muramyl dipeptide and toll-like receptor sensitivity in NOD2-associated Crohn's disease

31 March 2020

1 reference

Synergistic effect of muramyldipeptide with lipopolysaccharide or lipoteichoic acid to induce inflammatory cytokines in human monocytic cells in culture

31 March 2020

1 reference

Synergistic stimulation of human monocytes and dendritic cells by Toll-like receptor 4 and NOD1- and NOD2-activating agonists

31 March 2020

1 reference

Synergistic enhancement of Toll-like receptor responses by NOD1 activation

31 March 2020

1 reference

TLR signaling in the gut in health and disease

31 March 2020

1 reference

Decreased expression of Toll-like receptor-4 and MD-2 correlates with intestinal epithelial cell protection against dysregulated proinflammatory gene expression in response to bacterial lipopolysaccharide

31 March 2020

1 reference

TLR4 and MD-2 expression is regulated by immune-mediated signals in human intestinal epithelial cells

31 March 2020

1 reference

Human intestinal epithelial cells are broadly unresponsive to Toll-like receptor 2-dependent bacterial ligands: implications for host-microbial interactions in the gut.

31 March 2020

1 reference

Negative regulation of toll-like receptor-mediated signaling by Tollip

31 March 2020

1 reference

Recognition of commensal microflora by toll-like receptors is required for intestinal homeostasis

31 March 2020

1 reference

Epithelial cells pay a Toll for protection

31 March 2020

1 reference

Commensal host-bacterial relationships in the gut

31 March 2020

1 reference

CARD15 mutations in Blau syndrome

31 March 2020

1 reference

Early-onset sarcoidosis and CARD15 mutations with constitutive nuclear factor-kappaB activation: common genetic etiology with Blau syndrome

31 March 2020

1 reference

Both donor and recipient NOD2/CARD15 mutations associate with transplant-related mortality and GvHD following allogeneic stem cell transplantation

31 March 2020

1 reference

Nod1-mediated endothelial cell activation by Chlamydophila pneumoniae

31 March 2020

1 reference

Interactions between commensal intestinal bacteria and the immune system

31 March 2020

1 reference

Constitutive p40 promoter activation and IL-23 production in the terminal ileum mediated by dendritic cells

31 March 2020

1 reference

NOD2 mediates anti-inflammatory signals induced by TLR2 ligands: implications for Crohn's disease

31 March 2020

1 reference

Secretion of microbicidal alpha-defensins by intestinal Paneth cells in response to bacteria

31 March 2020

1 reference

Protection against enteric salmonellosis in transgenic mice expressing a human intestinal defensin

31 March 2020

1 reference

NOD2 (CARD15) mutations in Crohn's disease are associated with diminished mucosal alpha-defensin expression

31 March 2020

1 reference

Examining the Role of Paneth Cells in the Small Intestine by Lineage Ablation in Transgenic Mice

31 March 2020

1 reference

Regulation of intestinal alpha-defensin activation by the metalloproteinase matrilysin in innate host defense

31 March 2020

1 reference

Mucosal flora in inflammatory bowel disease

31 March 2020

1 reference

Enhanced Escherichia coli adherence and invasion in Crohn's disease and colon cancer

31 March 2020

1 reference

High prevalence of adherent-invasive Escherichia coli associated with ileal mucosa in Crohn’s disease

31 March 2020

1 reference

Regulation of IL-8 and IL-1beta expression in Crohn's disease associated NOD2/CARD15 mutations

31 March 2020

1 reference

Gene-environment interaction modulated by allelic heterogeneity in inflammatory diseases.

31 March 2020

1 reference

Helicobacter pylori infection and the development of gastric cancer

31 March 2020

1 reference

Genetic variation in DLG5 is associated with inflammatory bowel disease

31 March 2020

1 reference

The immunological and genetic basis of inflammatory bowel disease

31 March 2020

1 reference

The immunology of mucosal models of inflammation

31 March 2020

1 reference

Bacterial flagellin is a dominant antigen in Crohn disease.

31 March 2020

1 reference

Insights into the mechanism of oral tolerance derived from the study of models of mucosal inflammation

31 March 2020

1 reference

31 March 2020

Identifiers

DOI

10.1038/NRI1747

1 reference

Consolidated OpenCitations Corpus – April 2017

1 reference

Consolidated OpenCitations Corpus – April 2017

PubMed publication ID

16493424

1 reference

Consolidated OpenCitations Corpus – April 2017