Methanocarba analogues of purine nucleosides as potent and selective adenosine receptor agonists. (Q36316924)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10841798%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

title

Methanocarba analogues of purine nucleosides as potent and selective adenosine receptor agonists (English)

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7 November 2019

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7 November 2019

X Ji

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7 November 2019

A H Li

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7 November 2019

N Melman

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7 November 2019

M A Siddiqui

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7 November 2019

K J Shin

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7 November 2019

V E Marquez

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7 November 2019

R G Ravi

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7 November 2019

language of work or name

English

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publication date

1 June 2000

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Journal of Medicinal Chemistry

7 November 2019

published in

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7 November 2019

volume

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7 November 2019

issue

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7 November 2019

page(s)

2196-2203

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A3-adenosine receptors: design of selective ligands and therapeutic prospects

7 November 2019

cites work

1 reference

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Construction of the bicyclo[3.1.0]hexane template of a conformationally locked carbocyclic adenosine via an olefin keto-carbene cycloaddition

30 September 2017

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Use of the triazolotriazine [3H]ZM 241385 as a radioligand at recombinant human A2B adenosine receptors

30 September 2017

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Selective inhibition of cocaine-seeking behaviour by a partial dopamine D3 receptor agonist

30 September 2017

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Partial agonists and G protein-coupled receptor desensitization

30 September 2017

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Indirect modulation of dopamine D2 receptors as potential pharmacotherapy for schizophrenia: I. Adenosine agonists

30 September 2017

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Adenosine A3 receptors: novel ligands and paradoxical effects

30 September 2017

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Human P2Y1 receptor: molecular modeling and site-directed mutagenesis as tools to identify agonist and antagonist recognition sites.

30 September 2017

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Pharmacological characterization of novel A3 adenosine receptor-selective antagonists

30 September 2017

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A novel cardioprotective function of adenosine A1 and A3 receptors during prolonged simulated ischemia

30 September 2017

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Activation of adenosine A3 receptors on macrophages inhibits tumor necrosis factor-alpha

30 September 2017

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Structure-activity relationships of N6-benzyladenosine-5'-uronamides as A3-selective adenosine agonists

30 September 2017

1 reference

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2-Substitution of N6-benzyladenosine-5'-uronamides enhances selectivity for A3 adenosine receptors

30 September 2017

1 reference

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Adenosine A3 receptor stimulation and cerebral ischemia

30 September 2017

1 reference

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Search for new purine- and ribose-modified adenosine analogues as selective agonists and antagonists at adenosine receptors

30 September 2017

1 reference

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Comparative molecular field analysis of selective A3 adenosine receptor agonists

30 September 2017

1 reference

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Influence of G protein type on agonist efficacy

30 September 2017

1 reference

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Adenosine receptor activation and nociception

29 June 2018

1 reference

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2'-C-Methyl analogues of selective adenosine receptor agonists: synthesis and binding studies

29 June 2018

1 reference

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5'-substituted adenosine analogs as new high-affinity partial agonists for the adenosine A1 receptor

29 June 2018

1 reference

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Nucleosides with a twist. Can fixed forms of sugar ring pucker influence biological activity in nucleosides and oligonucleotides?

29 June 2018

1 reference

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Hypotensive and renal vasodilator effects of carbocyclic adenosine (aristeromycin) in anesthetized spontaneously hypertensive rats.

29 June 2018

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Effects of adenosine A2 receptor agonists on nucleoside transport

29 June 2018

1 reference

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Differences between natural and recombinant G protein-coupled receptor systems with varying receptor/G protein stoichiometry

29 June 2018

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Interaction of full and partial agonists of the A1 adenosine receptor with receptor/G protein complexes in rat brain membranes.

22 September 2018

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Repeated administration of selective adenosine A1 and A2 receptor agonists in the spontaneously hypertensive rat: tolerance develops to A1-mediated hemodynamic effects

22 September 2018

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The cardiac effects of a novel A1-adenosine receptor agonist in guinea pig isolated heart.

22 September 2018

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Conformationally restricted nucleosides. The reaction of adenosine deaminase with substrates built on a bicyclo[3.1.0]hexane template

22 September 2018

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12 December 2020

Cardiovascular pharmacology of the adenosine A1/A2-receptor agonist AMP 579: coronary hemodynamic and cardioprotective effects in the canine myocardium

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12 December 2020

Synthesis, Biological Activity, and Molecular Modeling of Ribose-Modified Deoxyadenosine Bisphosphate Analogues as P2Y1Receptor Ligands

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12 December 2020

Conformationally locked nucleoside analogues. Synthesis of dideoxycarbocyclic nucleoside analogues structurally related to neplanocin C

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12 December 2020

Specific transcriptional inhibition of bone marrow-derived macrophage tumor necrosis factor-alpha gene expression and protein production using novel enantiomeric carbocyclic nucleoside analogues

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12 December 2020

Conformational analysis of the sugar ring in nucleosides and nucleotides. New description using the concept of pseudorotation

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12 December 2020

Time course of action of three adenosine A1 receptor agonists with differing lipophilicity in rats: comparison of pharmacokinetic, haemodynamic and EEG effects

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12 December 2020

Identifiers

DOI

10.1021/JM9905965

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10841798%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

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7 November 2019

PubMed publication ID

10841798

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10841798%20AND%20SRC:MED&resulttype=core&format=json