Methanocarba analogues of purine nucleosides as potent and selective adenosine receptor agonists. (Q36316924)

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English	Methanocarba analogues of purine nucleosides as potent and selective adenosine receptor agonists.	scientific article

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7 November 2019

Methanocarba analogues of purine nucleosides as potent and selective adenosine receptor agonists (English)

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7 November 2019

Kenneth A. Jacobson

1

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7 November 2019

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X Ji

2

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7 November 2019

A H Li

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7 November 2019

N Melman

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7 November 2019

M A Siddiqui

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7 November 2019

K J Shin

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7 November 2019

V E Marquez

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7 November 2019

R G Ravi

8

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7 November 2019

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1 June 2000

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7 November 2019

Journal of Medicinal Chemistry

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7 November 2019

43

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7 November 2019

11

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7 November 2019

2196-2203

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7 November 2019

A3-adenosine receptors: design of selective ligands and therapeutic prospects

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30 September 2017

Construction of the bicyclo[3.1.0]hexane template of a conformationally locked carbocyclic adenosine via an olefin keto-carbene cycloaddition

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30 September 2017

Use of the triazolotriazine [3H]ZM 241385 as a radioligand at recombinant human A2B adenosine receptors

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30 September 2017

Selective inhibition of cocaine-seeking behaviour by a partial dopamine D3 receptor agonist

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30 September 2017

Partial agonists and G protein-coupled receptor desensitization

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30 September 2017

Indirect modulation of dopamine D2 receptors as potential pharmacotherapy for schizophrenia: I. Adenosine agonists

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30 September 2017

Adenosine A3 receptors: novel ligands and paradoxical effects

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30 September 2017

Human P2Y1 receptor: molecular modeling and site-directed mutagenesis as tools to identify agonist and antagonist recognition sites.

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30 September 2017

Pharmacological characterization of novel A3 adenosine receptor-selective antagonists

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30 September 2017

A novel cardioprotective function of adenosine A1 and A3 receptors during prolonged simulated ischemia

1 reference

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30 September 2017

Activation of adenosine A3 receptors on macrophages inhibits tumor necrosis factor-alpha

1 reference

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30 September 2017

Structure-activity relationships of N6-benzyladenosine-5'-uronamides as A3-selective adenosine agonists

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30 September 2017

2-Substitution of N6-benzyladenosine-5'-uronamides enhances selectivity for A3 adenosine receptors

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30 September 2017

Adenosine A3 receptor stimulation and cerebral ischemia

1 reference

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30 September 2017

Search for new purine- and ribose-modified adenosine analogues as selective agonists and antagonists at adenosine receptors

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30 September 2017

Comparative molecular field analysis of selective A3 adenosine receptor agonists

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30 September 2017

Influence of G protein type on agonist efficacy

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29 June 2018

Adenosine receptor activation and nociception

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29 June 2018

2'-C-Methyl analogues of selective adenosine receptor agonists: synthesis and binding studies

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29 June 2018

5'-substituted adenosine analogs as new high-affinity partial agonists for the adenosine A1 receptor

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29 June 2018

Nucleosides with a twist. Can fixed forms of sugar ring pucker influence biological activity in nucleosides and oligonucleotides?

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29 June 2018

Hypotensive and renal vasodilator effects of carbocyclic adenosine (aristeromycin) in anesthetized spontaneously hypertensive rats.

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29 June 2018

Effects of adenosine A2 receptor agonists on nucleoside transport

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29 June 2018

Differences between natural and recombinant G protein-coupled receptor systems with varying receptor/G protein stoichiometry

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22 September 2018

Interaction of full and partial agonists of the A1 adenosine receptor with receptor/G protein complexes in rat brain membranes.

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22 September 2018

Repeated administration of selective adenosine A1 and A2 receptor agonists in the spontaneously hypertensive rat: tolerance develops to A1-mediated hemodynamic effects

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22 September 2018

The cardiac effects of a novel A1-adenosine receptor agonist in guinea pig isolated heart.

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22 September 2018

Conformationally restricted nucleosides. The reaction of adenosine deaminase with substrates built on a bicyclo[3.1.0]hexane template

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Cardiovascular pharmacology of the adenosine A1/A2-receptor agonist AMP 579: coronary hemodynamic and cardioprotective effects in the canine myocardium

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Specific transcriptional inhibition of bone marrow-derived macrophage tumor necrosis factor-alpha gene expression and protein production using novel enantiomeric carbocyclic nucleoside analogues

1 reference

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Conformational analysis of the sugar ring in nucleosides and nucleotides. New description using the concept of pseudorotation

1 reference

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Time course of action of three adenosine A1 receptor agonists with differing lipophilicity in rats: comparison of pharmacokinetic, haemodynamic and EEG effects

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10.1021/JM9905965

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7 November 2019

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7 November 2019

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7 November 2019

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