Whole Gene Capture Analysis of 15 CRC Susceptibility Genes in Suspected Lynch Syndrome Patients. (Q36051960)

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13 March 2020

title

Whole Gene Capture Analysis of 15 CRC Susceptibility Genes in Suspected Lynch Syndrome Patients (English)

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Hans Morreau

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Anne M L Jansen

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Marije A Geilenkirchen

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Tom van Wezel

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Shantie C Jagmohan-Changur

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Dina Ruano

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Heleen M van der Klift

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Brendy E W M van den Akker

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Michiel van Galen

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Anja Wagner

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Tom G W Letteboer

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Encarna B Gómez-García

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Carli M J Tops

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Juul T Wijnen

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language of work or name

English

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publication date

14 June 2016

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volume

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page(s)

e0157381

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Creative Commons Attribution 4.0 International

13 March 2020

start time

14 June 2016

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April 2022 Public Data File from Crossref

copyrighted

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cites work

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EPCAM deletion carriers constitute a unique subgroup of Lynch syndrome patients

2 October 2017

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Lynch or not Lynch? Is that always a question?

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Evidence of constitutional MLH1 epimutation associated to transgenerational inheritance of cancer susceptibility

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2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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Splicing analysis for exonic and intronic mismatch repair gene variants associated with Lynch syndrome confirms high concordance between minigene assays and patient RNA analyses

2 October 2017

1 reference

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One to 2-year surveillance intervals reduce risk of colorectal cancer in families with Lynch syndrome

11 July 2018

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Association of MUTYH and colorectal cancer

11 July 2018

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11 July 2018

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Prevalence of germline MUTYH mutations among Lynch-like syndrome patients

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4907507

Somatic mutations in MLH1 and MSH2 are a frequent cause of mismatch-repair deficiency in Lynch syndrome-like tumors

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4907507

Risk of cancer in cases of suspected lynch syndrome without germline mutation.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4907507

Germline hypermethylation of MLH1 and EPCAM deletions are a frequent cause of Lynch syndrome

23 September 2018

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Heritable somatic methylation and inactivation of MSH2 in families with Lynch syndrome due to deletion of the 3' exons of TACSTD1.

23 September 2018

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Inheritance of a Cancer-AssociatedMLH1Germ-Line Epimutation

23 September 2018

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Germline epimutation of MLH1 in individuals with multiple cancers

23 September 2018

1 reference

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Extensive but hemiallelic methylation of the hMLH1 promoter region in early-onset sporadic colon cancers with microsatellite instability

23 September 2018

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23 September 2018

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Crossref

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0157381

Replication errors in benign and malignant tumors from hereditary nonpolyposis colorectal cancer patients

21 January 2018

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12 December 2020

Coexisting somatic promoter hypermethylation and pathogenic MLH1 germline mutation in Lynch syndrome

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12 December 2020

The International Collaborative Group on Hereditary Non-Polyposis Colorectal Cancer (ICG-HNPCC)

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12 December 2020

MLH1 germline epimutations in selected patients with early-onset non-polyposis colorectal cancer

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12 December 2020

Colorectal cancer in a monoallelic MYH mutation carrier

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12 December 2020

MLH1 promotor hypermethylation does not rule out a diagnosis of Lynch syndrome: a case report

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12 December 2020

Intronic variants in BRCA1 and BRCA2 that affect RNA splicing can be reliably selected by splice-site prediction programs

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12 December 2020

Further evidence for heritability of an epimutation in one of 12 cases with MLH1 promoter methylation in blood cells clinically displaying HNPCC

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12 December 2020

10.1371/JOURNAL.PONE.0157381

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27300758%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

0 references

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13 March 2020

PubMed publication ID

27300758

1 reference

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