Germline variants in POLE are associated with early onset mismatch repair deficient colorectal cancer (Q35154300)

25370038

6 August 2017

title

Germline variants in POLE are associated with early onset mismatch repair deficient colorectal cancer (English)

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6 August 2017

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7 June 2020

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7 June 2020

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7 June 2020

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7 June 2020

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7 June 2020

Hans Morreau

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7 June 2020

Fadwa A Elsayed

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7 June 2020

C Marleen Kets

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7 June 2020

Dina Ruano

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7 June 2020

Brendy van den Akker

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7 June 2020

Melanie Schrumpf

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7 June 2020

Juul T Wijnen

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7 June 2020

Carli M Tops

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7 June 2020

Marjolijn J Ligtenberg

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7 June 2020

publication date

5 November 2014

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25370038

European Journal of Human Genetics

6 August 2017

published in

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volume

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issue

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7 June 2020

page(s)

1080-1084

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Biallelic MUTYH mutations can mimic Lynch syndrome

7 June 2020

cites work

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4351893

New insights into POLE and POLD1 germline mutations in familial colorectal cancer and polyposis

13 July 2018

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Colorectal cancer risk variants on 11q23 and 15q13 are associated with unexplained adenomatous polyposis

13 July 2018

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The landscape of microsatellite instability in colorectal and endometrial cancer genomes

13 July 2018

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Germline mutations affecting the proofreading domains of POLE and POLD1 predispose to colorectal adenomas and carcinomas

13 July 2018

1 reference

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Comprehensive molecular characterization of human colon and rectal cancer

13 July 2018

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Rapid KRAS, EGFR, BRAF and PIK3CA mutation analysis of fine needle aspirates from non-small-cell lung cancer using allele-specific qPCR.

13 July 2018

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Concurrent genetic alterations in DNA polymerase proofreading and mismatch repair in human colorectal cancer

13 July 2018

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DNA replication fidelity and cancer

13 July 2018

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Germline MutY human homologue mutations and colorectal cancer: a multisite case-control study

13 July 2018

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The fidelity of DNA synthesis by eukaryotic replicative and translesion synthesis polymerases

13 July 2018

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Mutation at the polymerase active site of mouse DNA polymerase delta increases genomic instability and accelerates tumorigenesis

13 July 2018

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The role of MYH and microsatellite instability in the development of sporadic colorectal cancer

13 July 2018

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Heritable germline epimutation of MSH2 in a family with hereditary nonpolyposis colorectal cancer

13 July 2018

1 reference

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DNA polymerases that propagate the eukaryotic DNA replication fork

13 July 2018

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Yeast DNA polymerases and their role at the replication fork.

13 July 2018

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Eukaryotic DNA polymerase amino acid sequence required for 3'----5' exonuclease activity

13 July 2018

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The 3' to 5' exonuclease activity located in the DNA polymerase delta subunit of Saccharomyces cerevisiae is required for accurate replication

13 July 2018

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Somatic mutations in MLH1 and MSH2 are a frequent cause of mismatch-repair deficiency in Lynch syndrome-like tumors

13 July 2018

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The burden of faulty proofreading in colon cancer

27 September 2018

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MYH biallelic mutation can inactivate the two genetic pathways of colorectal cancer by APC or MLH1 transversions.

27 September 2018

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Enrichment of low penetrance susceptibility loci in a Dutch familial colorectal cancer cohort

27 September 2018

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Somatic APC mosaicism: an underestimated cause of polyposis coli.

27 September 2018

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Microsatellite instability, immunohistochemistry, and additional PMS2 staining in suspected hereditary nonpolyposis colorectal cancer

27 September 2018

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Base selection, proofreading, and mismatch repair during DNA replication in Escherichia coli.

27 September 2018

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27 September 2018

Identifiers

DOI

10.1038/EJHG.2014.242

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Dimensions Publication ID

7 June 2020

0 references

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7 June 2020

25370038

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