Incidence and functional consequences of hMLH1 promoter hypermethylation in colorectal carcinoma (Q29615026)

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scientific article (publication date: 9 June 1998)

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English	Incidence and functional consequences of hMLH1 promoter hypermethylation in colorectal carcinoma	scientific article (publication date: 9 June 1998)

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title

Incidence and functional consequences of hMLH1 promoter hypermethylation in colorectal carcinoma (English)

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PubMed

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=9618505

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main subject

hypermethylation

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inferred from title

colorectal carcinoma

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author

Bert Vogelstein

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Vogelstein B

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Kenneth W. Kinzler

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Kinzler KW

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author name string

Herman JG

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1

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Umar A

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Polyak K

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Graff JR

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Ahuja N

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Issa JP

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Markowitz S

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Willson JK

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Hamilton SR

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9

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Kane MF

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Kolodner RD

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Kunkel TA

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Baylin SB

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language of work or name

English

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publication date

9 June 1998

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published in

Proceedings of the National Academy of Sciences of the United States of America

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volume

95

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issue

12

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page(s)

6870-5

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Methylation of the hMLH1 promoter correlates with lack of expression of hMLH1 in sporadic colon tumors and mismatch repair-defective human tumor cell lines

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Silencing of the VHL tumor-suppressor gene by DNA methylation in renal carcinoma

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5′ CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancers

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Loss of the wild type MLH1 gene is a feature of hereditary nonpolyposis colorectal cancer

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Mismatch repair gene defects in sporadic colorectal cancers with microsatellite instability

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Inactivation of the CDKN2/p16/MTS1 gene is frequently associated with aberrant DNA methylation in all common human cancers

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PubMed

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Somatic mutations in the hMSH2 gene in microsatellite unstable colorectal carcinomas

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PubMed

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12 December 2020

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Analysis of mismatch repair genes in hereditary non–polyposis colorectal cancer patients

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/9618505

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12 December 2020

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Microsatellite instability and mismatch repair defects in cancer

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https://pubmed.ncbi.nlm.nih.gov/9618505

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12 December 2020

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Microsatellite instability and the role of hMSH2 in sporadic colorectalcancer

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12 December 2020

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Altered expression of hMSH2 and hMLH1 in tumors with microsatellite instability and genetic alterations in mismatch repair genes

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MSH2 andMLH1 mutations in sporadic replication error-positive colorectal carcinoma as assessed by two-dimensional DNA electrophoresis

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Association between CpG island methylation and microsatellite instability in colorectal cancer

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Hypermethylation in the retinoblastoma gene is associated with unilateral, sporadic retinoblastoma

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Identifiers

DOI

10.1073/PNAS.95.12.6870

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stated in

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

270420

ADS bibcode

1998PNAS...95.6870H

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OpenCitations bibliographic resource ID

270420

1 reference

stated in

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

270420

PMC publication ID

22665

2 references

stated in

PubMed

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=9618505

retrieved

30 April 2017

stated in

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

270420

PubMed publication ID

9618505

2 references

stated in

PubMed

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=9618505

retrieved

30 April 2017

stated in

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

270420

ResearchGate publication ID

235611318

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