The mitochondrial ATP-dependent Lon protease: a novel target in lymphoma death mediated by the synthetic triterpenoid CDDO and its derivatives (Q35876952)

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scientific article published on 8 February 2012

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English	The mitochondrial ATP-dependent Lon protease: a novel target in lymphoma death mediated by the synthetic triterpenoid CDDO and its derivatives	scientific article published on 8 February 2012

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

The mitochondrial ATP-dependent Lon protease: a novel target in lymphoma death mediated by the synthetic triterpenoid CDDO and its derivatives (English)

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Michael Andreeff

10

object named as

Michael Andreeff

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10 August 2017

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author name string

Steven H Bernstein

1

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10 August 2017

Sundararajan Venkatesh

2

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10 August 2017

Min Li

3

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10 August 2017

Jae Lee

4

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10 August 2017

Bin Lu

5

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PMC publication ID

10 August 2017

Shannon P Hilchey

6

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Europe PubMed Central

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10 August 2017

Kimberly M Morse

7

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Europe PubMed Central

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10 August 2017

Hollie M Metcalfe

8

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10 August 2017

Jolanta Skalska

9

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10 August 2017

Paul S Brookes

11

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10 August 2017

Carolyn K Suzuki

12

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10 August 2017

language of work or name

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publication date

8 February 2012

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10 August 2017

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10 August 2017

119

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10 August 2017

14

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10 August 2017

3321-3329

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Europe PubMed Central

PMC publication ID

10 August 2017

Multitasking in the mitochondrion by the ATP-dependent Lon protease

1 reference

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Mitochondrial Lon protease regulates mitochondrial DNA copy number and transcription by selective degradation of mitochondrial transcription factor A (TFAM)

1 reference

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Turnover of mitochondrial steroidogenic acute regulatory (StAR) protein by Lon protease: the unexpected effect of proteasome inhibitors.

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Roles for the human ATP-dependent Lon protease in mitochondrial DNA maintenance

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The triterpenoid 2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid and its derivatives elicit human lymphoid cell apoptosis through a novel pathway involving the unregulated mitochondrial permeability transition pore

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2-cyano-3,12-dioxooleana-1,9(11)-diene-28-oic acid disrupts microtubule polymerization: a possible mechanism contributing to apoptosis

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2-Cyano-3,12-dioxooleana-1,9-dien-28-imidazolide (CDDO-Im) directly targets mitochondrial glutathione to induce apoptosis in pancreatic cancer

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Cleavage site selection within a folded substrate by the ATP-dependent lon protease

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Downregulation of the human Lon protease impairs mitochondrial structure and function and causes cell death

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The ATP-dependent Lon protease of Mus musculus is a DNA-binding protein that is functionally conserved between yeast and mammals

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1 reference

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10.1182/BLOOD-2011-02-340075

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Europe PubMed Central

PMC publication ID

10 August 2017

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Europe PubMed Central

PMC publication ID

10 August 2017

PubMed publication ID

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Europe PubMed Central

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10 August 2017

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