Impaired in vivo mitochondrial Krebs cycle activity after myocardial infarction assessed using hyperpolarized magnetic resonance spectroscopy. (Q35668391)

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scientific article published on 8 September 2014

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English	Impaired in vivo mitochondrial Krebs cycle activity after myocardial infarction assessed using hyperpolarized magnetic resonance spectroscopy.	scientific article published on 8 September 2014

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16 February 2020

Impaired in vivo mitochondrial Krebs cycle activity after myocardial infarction assessed using hyperpolarized magnetic resonance spectroscopy (English)

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16 February 2020

myocardial infarction

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Carolyn A. Carr

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Daniel J Stuckey

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Damian J. Tyler

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George K. Radda

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George K Radda

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Helen J Atherton

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James A West

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Kieran Clarke

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Lisa C Heather

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Julian L Griffin

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8 September 2014

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Circulation: Cardiovascular Imaging

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895-904

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16 February 2020

describes a project that uses

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Metabolic imaging of patients with prostate cancer using hyperpolarized [1-¹³C]pyruvate

1 reference

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The cycling of acetyl-coenzyme A through acetylcarnitine buffers cardiac substrate supply: a hyperpolarized 13C magnetic resonance study.

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Validation of the in vivo assessment of pyruvate dehydrogenase activity using hyperpolarised 13C MRS.

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Experimental myocardium infarction in rats: analysis of the model

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Substrate-enzyme competition attenuates upregulated anaplerotic flux through malic enzyme in hypertrophied rat heart and restores triacylglyceride content: attenuating upregulated anaplerosis in hypertrophy

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12 July 2018

In vivo assessment of pyruvate dehydrogenase flux in the heart using hyperpolarized carbon-13 magnetic resonance

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12 July 2018

Hyperpolarized 13C allows a direct measure of flux through a single enzyme-catalyzed step by NMR.

1 reference

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12 July 2018

The failing heart--an engine out of fuel

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12 July 2018

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Healing after myocardial infarction

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Paradoxical downregulation of the glucose oxidation pathway despite enhanced flux in severe heart failure

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Defective lipid metabolism in the failing heart

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Metabolic imaging of acute and chronic infarction in the perfused rat heart using hyperpolarised [1-13C]pyruvate.

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Isoproterenol induces in vivo functional and metabolic abnormalities: similar to those found in the infarcted rat heart

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Critical role of complex III in the early metabolic changes following myocardial infarction

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1 reference

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1 reference

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Control of citric acid cycle activity in rat heart mitochondria

1 reference

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1 reference

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1 reference

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1 reference

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Creatine kinase system in failing and nonfailing human myocardium

1 reference

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1 reference

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Identifiers

10.1161/CIRCIMAGING.114.001857

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16 February 2020

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16 February 2020

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16 February 2020

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