Validation of the in vivo assessment of pyruvate dehydrogenase activity using hyperpolarised 13C MRS. (Q42108807)

16 October 2017

Validation of the in vivo assessment of pyruvate dehydrogenase activity using hyperpolarised 13C MRS. (English)

1 reference

16 October 2017

Michael S Dodd

0 references

Damian J Tyler

0 references

George K Radda

1 reference

16 October 2017

Helen J Atherton

1 reference

16 October 2017

Marie A Schroeder

1 reference

16 October 2017

Lisa C Heather

1 reference

16 October 2017

Emma E Carter

1 reference

16 October 2017

Lowri E Cochlin

1 reference

16 October 2017

Simon Nagel

1 reference

16 October 2017

Nicola R Sibson

1 reference

16 October 2017

Kieran Clarke

1 reference

16 October 2017

26 August 2010

1 reference

16 October 2017

1 reference

16 October 2017

1 reference

16 October 2017

1 reference

16 October 2017

201-208

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Kinetic modeling of hyperpolarized 13C1-pyruvate metabolism in normal rats and TRAMP mice

16 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4604661

Real-time assessment of Krebs cycle metabolism using hyperpolarized 13C magnetic resonance spectroscopy.

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4604661

In vivo assessment of pyruvate dehydrogenase flux in the heart using hyperpolarized carbon-13 magnetic resonance

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4604661

Hyperpolarized 13C allows a direct measure of flux through a single enzyme-catalyzed step by NMR.

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4604661

Real-time metabolic imaging

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4604661

Myocardial substrate metabolism in the normal and failing heart

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4604661

Increase in signal-to-noise ratio of > 10,000 times in liquid-state NMR

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4604661

Java-based graphical user interface for MRUI, a software package for quantitation of in vivo/medical magnetic resonance spectroscopy signals

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4604661

Substrate availability limits human skeletal muscle oxidative ATP regeneration at the onset of ischemic exercise

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4604661

Starvation and diabetes increase the amount of pyruvate dehydrogenase kinase isoenzyme 4 in rat heart

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4604661

Molecular Mechanisms Underlying the Long-term Impact of Dietary Fat to Increase Cardiac Pyruvate Dehydrogenase Kinase: Regulation by Insulin, Cyclic AMP and Pyruvate

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4604661

Energy metabolism of the heart: from basic concepts to clinical applications

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4604661

Role of pyruvate carboxylation in the energy-linked regulation of pool sizes of tricarboxylic acid-cycle intermediates in the myocardium

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4604661

Fuel selection in animals

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4604661

Pyruvate dehydrogenase activities during the fed-to-starved transition and on re-feeding after acute or prolonged starvation

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4604661

Relative importance of pyruvate dehydrogenase interconversion and feed-back inhibition in the effect of fatty acids on pyruvate oxidation by rat heart mitochondria

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4604661

Stimulation of phosphorylation and inactivation of pyruvate dehydrogenase by physiological inhibitors of the pyruvate dehydrogenase reaction

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4604661

Investigation of [18F]2-fluoro-2-deoxyglucose for the measure of myocardial glucose metabolism

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4604661

The effect of hyperpolarized tracer concentration on myocardial uptake and metabolism

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4604661

Activation of pyruvate dehydrogenase in perfused rat heart by dichloroacetate (Short Communication).

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4604661

Regulation of pyruvate dehydrogenase activity and citric acid cycle intermediates during high cardiac power generation

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4604661

Control of cardiac pyruvate dehydrogenase activity in peroxisome proliferator-activated receptor-alpha transgenic mice

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4604661

Physical exercise-induced hyperinsulinemic hypoglycemia is an autosomal-dominant trait characterized by abnormal pyruvate-induced insulin release

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4604661

Impaired myocardial fatty acid oxidation and reduced protein expression of retinoid X receptor-alpha in pacing-induced heart failure

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4604661

Fuel-sensing mechanisms integrating lipid and carbohydrate utilization

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4604661

Blood pyruvate recovery curves after short heavy submaximal exercise in man.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4604661

Metabolic compartmentation of pyruvate in the isolated perfused rat heart

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4604661

Measuring intracellular pH in the heart using hyperpolarized carbon dioxide and bicarbonate: a 13C and 31P magnetic resonance spectroscopy study

17 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1002%2FNBM.1573

Relationshiop between phosphorylation and activity of pyruvate dehydrogenase in rat liver mitochondria and the absence of such a relationship for pyruvate carboxylase

21 January 2018

1 reference

12 December 2020

Regulation of mammalian pyruvate dehydrogenase complex by a phosphorylation-dephosphorylation cycle

1 reference

12 December 2020

Metabolic control of enzymes in normal, Diabetic, and diabetic insulin-treated rats utilizing 1,3 butanediol

1 reference

12 December 2020

Metabolic heterogeneity of carbon substrate utilization in mammalian heart: NMR determinations of mitochondrial versus cytosolic compartmentation

1 reference

12 December 2020

Studies on the peripheral circulation and metabolism in man. 1. Oxygen utilization and lactate-pyruvate formation in the legs at rest and during exercise in healthy subjects

1 reference

12 December 2020

Ranolazine increases active pyruvate dehydrogenase in perfused normoxic rat hearts: evidence for an indirect mechanism

1 reference

12 December 2020

Long-term regulation of pyruvate dehydrogenase kinase by high-fat feeding. Experiments in vivo and in cultured cardiomyocytes

1 reference

12 December 2020

Muscle acetyl group availability is a major determinant of oxygen deficit in humans during submaximal exercise

1 reference

12 December 2020

High-fat feeding alters the response of rat PDH complex to acute changes in glucose and insulin

1 reference

12 December 2020

The Effects of Hypertrophy and Diabetes on Cardiac Pyruvate Dehydrogenase Activity

1 reference

12 December 2020

Identifiers

DOI

10.1002/NBM.1573

1 reference

16 October 2017

1 reference

16 October 2017

PubMed publication ID

20799252

1 reference