Sustained regression of tumors upon MYC inactivation requires p53 or thrombospondin-1 to reverse the angiogenic switch. (Q35133764)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17056717%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

title

Sustained regression of tumors upon MYC inactivation requires p53 or thrombospondin-1 to reverse the angiogenic switch (English)

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21 December 2019

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21 December 2019

Jan van Riggelen

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21 December 2019

Judah Folkman

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21 December 2019

Emmanuelle Passegué

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21 December 2019

Sandra Ryeom

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21 December 2019

Alice C Fan

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21 December 2019

Pavan Bachireddy

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21 December 2019

Ryan C Lynch

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21 December 2019

Matthew J Rioth

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21 December 2019

Andrew M Kopelman

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21 December 2019

Flora Tang

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21 December 2019

Dean W Felsher

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21 December 2019

language of work or name

English

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publication date

20 October 2006

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Proceedings of the National Academy of Sciences of the United States of America

21 December 2019

published in

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21 December 2019

volume

103

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21 December 2019

issue

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21 December 2019

page(s)

16266-16271

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Loss of p53 impedes the antileukemic response to BCR-ABL inhibition

21 December 2019

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Impact of p53 loss on reversal and recurrence of conditional Wnt-induced tumorigenesis

13 July 2018

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13 July 2018

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13 July 2018

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13 July 2018

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13 July 2018

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Multiple BCR-ABL kinase domain mutations confer polyclonal resistance to the tyrosine kinase inhibitor imatinib (STI571) in chronic phase and blast crisis chronic myeloid leukemia

13 July 2018

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Cancer. Addiction to oncogenes--the Achilles heal of cancer

13 July 2018

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Disabling Abl-perspectives on Abl kinase regulation and cancer therapeutics

13 July 2018

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Thrombospondin-1 as an endogenous inhibitor of angiogenesis and tumor growth.

13 July 2018

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13 July 2018

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Thrombospondin-1 suppresses spontaneous tumor growth and inhibits activation of matrix metalloproteinase-9 and mobilization of vascular endothelial growth factor

13 July 2018

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13 July 2018

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13 July 2018

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c-MYC induces mammary tumorigenesis by means of a preferred pathway involving spontaneous Kras2 mutations

13 July 2018

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Activation of the myc oncoprotein leads to increased turnover of thrombospondin-1 mRNA

13 July 2018

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Disruption of the ARF-Mdm2-p53 tumor suppressor pathway in Myc-induced lymphomagenesis

13 July 2018

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13 July 2018

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13 July 2018

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13 July 2018

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13 July 2018

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The MMTV/c-myc transgene and p53 null alleles collaborate to induce T-cell lymphomas, but not mammary carcinomas in transgenic mice.

13 July 2018

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The p53 tumor suppressor gene inhibits angiogenesis by stimulating the production of thrombospondin.

13 July 2018

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13 July 2018

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13 July 2018

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Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

13 July 2018

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13 July 2018

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Antiangiogenic therapy and p53.

27 September 2018

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A non-transgenic mouse model for B-cell lymphoma: in vivo infection of p53-null bone marrow progenitors by a Myc retrovirus is sufficient for tumorigenesis.

27 September 2018

1 reference

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Effect of p53 status on tumor response to antiangiogenic therapy

27 September 2018

1 reference

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A transactivation-deficient mouse model provides insights into Trp53 regulation and function

27 September 2018

1 reference

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Gemcitabine doublets in advanced urothelial cancer

27 September 2018

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Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0608017103

Sustained loss of a neoplastic phenotype by brief inactivation of MYC

21 January 2018

1 reference

12 December 2020

Angiogenesis is an early event in the generation of myc-induced lymphomas

1 reference

12 December 2020

Genomically complex lymphomas undergo sustained tumor regression upon MYC inactivation unless they acquire novel chromosomal translocations

1 reference

12 December 2020

Synergy between a human c-myc transgene and p53 null genotype in murine thymic lymphomas: contrasting effects of homozygous and heterozygous p53 loss

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12 December 2020

Identifiers

DOI

10.1073/PNAS.0608017103

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17056717%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

0 references

1 reference

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21 December 2019

PubMed publication ID

17056717

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17056717%20AND%20SRC:MED&resulttype=core&format=json