Force-dependent transition in the T-cell receptor β-subunit allosterically regulates peptide discrimination and pMHC bond lifetime (Q35062603)

6 August 2017

title

Force-dependent transition in the T-cell receptor β-subunit allosterically regulates peptide discrimination and pMHC bond lifetime (English)

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6 August 2017

Dibyendu Kumar Das

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6 August 2017

Yinnian Feng

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6 August 2017

Robert J Mallis

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6 August 2017

Xiaolong Li

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6 August 2017

Derin B Keskin

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6 August 2017

Rebecca E Hussey

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6 August 2017

Sonia K Brady

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6 August 2017

Jia-Huai Wang

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6 August 2017

Gerhard Wagner

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6 August 2017

Ellis L Reinherz

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6 August 2017

Matthew J Lang

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6 August 2017

language of work or name

English

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publication date

20 January 2015

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Proceedings of the National Academy of Sciences of the United States of America

6 August 2017

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inferred from page(s)

published in

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6 August 2017

volume

112

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6 August 2017

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6 August 2017

page(s)

1517-1522

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Insights into the initiation of TCR signaling

6 August 2017

cites work

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Accumulation of dynamic catch bonds between TCR and agonist peptide-MHC triggers T cell signaling.

8 July 2018

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Crystal Structure of Vδ1 T Cell Receptor in Complex with CD1d-Sulfatide Shows MHC-like Recognition of a Self-Lipid by Human γδ T Cells

8 July 2018

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The transcription factor IRF4 is essential for TCR affinity-mediated metabolic programming and clonal expansion of T cells

8 July 2018

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Direct single molecule measurement of TCR triggering by agonist pMHC in living primary T cells

8 July 2018

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Transcriptional control of effector and memory CD8+ T cell differentiation

8 July 2018

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The structural basis of αβ T-lineage immune recognition: TCR docking topologies, mechanotransduction, and co-receptor function

8 July 2018

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T cells and their eons-old obsession with MHC

8 July 2018

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A Conserved Hydrophobic Patch on Vβ Domains Revealed by TCRβ Chain Crystal Structures: Implications for Pre-TCR Dimerization

8 July 2018

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An evolutionary view of the mechanism for immune and genome diversity

8 July 2018

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Mechanosensing in T lymphocyte activation

8 July 2018

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Body-barrier surveillance by epidermal γδ TCRs

8 July 2018

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Force generation upon T cell receptor engagement

8 July 2018

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Distinctive CD3 heterodimeric ectodomain topologies maximize antigen-triggered activation of alpha beta T cell receptors

8 July 2018

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Constitutively active Lck kinase in T cells drives antigen receptor signal transduction

8 July 2018

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Single-molecule denaturation and degradation of proteins by the AAA+ ClpXP protease

8 July 2018

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The alphabeta T cell receptor is an anisotropic mechanosensor.

8 July 2018

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Demonstration of catch bonds between an integrin and its ligand.

8 July 2018

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The structure, regulation, and function of ZAP-70.

8 July 2018

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Stretching single talin rod molecules activates vinculin binding

8 July 2018

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Regulation of T Cell Receptor Activation by Dynamic Membrane Binding of the CD3ɛ Cytoplasmic Tyrosine-Based Motif

8 July 2018

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Matrix elasticity directs stem cell lineage specification

8 July 2018

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Solution structure of the CD3epsilondelta ectodomain and comparison with CD3epsilongamma as a basis for modeling T cell receptor topology and signaling

8 July 2018

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Thymic selection revisited: how essential is it?

8 July 2018

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An automated two-dimensional optical force clamp for single molecule studies

8 July 2018

1 reference

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Involvement of the TCR Cbeta FG loop in thymic selection and T cell function

8 July 2018

1 reference

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Mechanisms contributing to T cell receptor signaling and assembly revealed by the solution structure of an ectodomain fragment of the CD3 epsilon gamma heterodimer

8 July 2018

1 reference

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Structural basis of CD8 coreceptor function revealed by crystallographic analysis of a murine CD8alphaalpha ectodomain fragment in complex with H-2Kb

8 July 2018

1 reference

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Atomic structure of an alphabeta T cell receptor (TCR) heterodimer in complex with an anti-TCR fab fragment derived from a mitogenic antibody

8 July 2018

1 reference

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Kinetic proofreading in T-cell receptor signal transduction

8 July 2018

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Lifetime of the P-selectin-carbohydrate bond and its response to tensile force in hydrodynamic flow.

8 July 2018

1 reference

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Cutting Edge: mechanical forces acting on T cells immobilized via the TCR complex can trigger TCR signaling.

8 July 2018

1 reference

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Cloning and expression of murine Ig genes from single B cells.

27 September 2018

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27 September 2018

Real engines of creation

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12 December 2020

Evidence that a single peptide-MHC complex on a target cell can elicit a cytolytic T cell response

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12 December 2020

Thymic selection is influenced by subtle structural variation involving the p4 residue of an MHC class I-bound peptide

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12 December 2020

The CD8alphabeta co-receptor on double-positive thymocytes binds with differing affinities to the products of distinct class I MHC loci

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12 December 2020

The TCR C beta FG loop regulates alpha beta T cell development

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12 December 2020

Phosphorylation of T cell receptor zeta is regulated by a lipid dependent folding transition

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12 December 2020

Crystallization of a deglycosylated T cell receptor (TCR) complexed with an anti-TCR Fab fragment

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12 December 2020

Identifiers

DOI

10.1073/PNAS.1424829112

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6 August 2017

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6 August 2017

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