Distinctive CD3 heterodimeric ectodomain topologies maximize antigen-triggered activation of alpha beta T cell receptors (Q34113293)

31 July 2017

title

Distinctive CD3 heterodimeric ectodomain topologies maximize antigen-triggered activation of alpha beta T cell receptors (English)

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31 July 2017

Dietmar J Kappes

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31 July 2017

Sun Taek Kim

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31 July 2017

Maki Touma

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31 July 2017

Koh Takeuchi

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31 July 2017

Zhen-Yu J Sun

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31 July 2017

Vibhuti P Dave

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31 July 2017

Gerhard Wagner

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31 July 2017

Ellis L Reinherz

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31 July 2017

language of work or name

English

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publication date

26 July 2010

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31 July 2017

published in

Journal of Immunology

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31 July 2017

volume

185

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31 July 2017

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31 July 2017

page(s)

2951-2959

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The alphabeta T cell receptor is an anisotropic mechanosensor.

31 July 2017

cites work

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Surface-anchored monomeric agonist pMHCs alone trigger TCR with high sensitivity

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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T-cell receptor triggering is critically dependent on the dimensions of its peptide-MHC ligand.

5 July 2018

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5 July 2018

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Solution structure of the CD3epsilondelta ectodomain and comparison with CD3epsilongamma as a basis for modeling T cell receptor topology and signaling

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Specific requirement for CD3epsilon in T cell development.

5 July 2018

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Essential and partially overlapping role of CD3gamma and CD3delta for development of alphabeta and gammadelta T lymphocytes

5 July 2018

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Differential thymic selection outcomes stimulated by focal structural alteration in peptide/major histocompatibility complex ligands

5 July 2018

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The CD3gamma chain is essential for development of both the TCRalphabeta and TCRgammadelta lineages

5 July 2018

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5 July 2018

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CD3 delta deficiency arrests development of the alpha beta but not the gamma delta T cell lineage

5 July 2018

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Structure of the complex between human T-cell receptor, viral peptide and HLA-A2

5 July 2018

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Episomal vectors rapidly and stably produce high-titer recombinant retrovirus

5 July 2018

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Abnormal T cell development in CD3-zeta-/- mutant mice and identification of a novel T cell population in the intestine

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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The cytoplasmic domain of the T cell receptor zeta chain is sufficient to couple to receptor-associated signal transduction pathways

5 July 2018

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Sequence requirements for induction of cytolysis by the T cell antigen/Fc receptor zeta chain

5 July 2018

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Activation of T cells by a tyrosine kinase activation domain in the cytoplasmic tail of CD3 epsilon.

5 July 2018

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Vesicular stomatitis virus antigenic octapeptide N52-59 is anchored into the groove of the H-2Kb molecule by the side chains of three amino acids and the main-chain atoms of the amino terminus

5 July 2018

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Antigen ligation triggers a conformational change within the constant domain of the alphabeta T cell receptor

5 July 2018

1 reference

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Evidence for a stepwise evolution of the CD3 family

28 October 2018

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Positive selection through a motif in the alphabeta T cell receptor

28 October 2018

1 reference

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Biochemical analysis of the Xenopus laevis TCR/CD3 complex supports the "stepwise evolution" model

28 October 2018

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12 December 2020

The CD8alphabeta co-receptor on double-positive thymocytes binds with differing affinities to the products of distinct class I MHC loci

1 reference

12 December 2020

Evolution of T cell receptor (TCR) alpha beta heterodimer assembly with the CD3 complex

1 reference

12 December 2020

Distinct structure and signaling potential of the gamma delta TCR complex

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12 December 2020

T Cell Development in Mice that Lack the ζ Chain of the T Cell Antigen Receptor Complex

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12 December 2020

TCR signal strength influences alphabeta/gammadelta lineage fate

1 reference

12 December 2020

Different role for mouse and human CD3delta/epsilon heterodimer in preT cell receptor (preTCR) function: human CD3delta/epsilon heterodimer restores the defective preTCR function in CD3gamma- and CD3gammadelta-deficient mice

1 reference

12 December 2020

The TCR C beta FG loop regulates alpha beta T cell development

1 reference

12 December 2020

Overlapping functions of human CD3delta and mouse CD3gamma in alphabeta T-cell development revealed in a humanized CD3gamma-mouse

1 reference

12 December 2020

Full Activation of the T Cell Receptor Requires Both Clustering and Conformational Changes at CD3

1 reference

12 December 2020

Importance of the CD3gamma ectodomain terminal beta-strand and membrane proximal stalk in thymic development and receptor assembly

1 reference

12 December 2020

Identifiers

DOI

10.4049/JIMMUNOL.1000732

1 reference

31 July 2017

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31 July 2017

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