Memory deficits due to familial British dementia BRI2 mutation are caused by loss of BRI2 function rather than amyloidosis (Q34667384)

3 August 2017

title

Memory deficits due to familial British dementia BRI2 mutation are caused by loss of BRI2 function rather than amyloidosis (English)

1 reference

Familial British dementia

3 August 2017

0 references

1 reference

Luciano D'Adamio

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Ottavio Arancio

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Robert Tamayev

1 reference

3 August 2017

Luca Giliberto

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3 August 2017

Wei Li

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3 August 2017

Cristina d'Abramo

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3 August 2017

Ruben Vidal

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3 August 2017

language of work or name

English

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publication date

1 November 2010

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3 August 2017

published in

Journal of Neuroscience

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3 August 2017

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3 August 2017

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3 August 2017

page(s)

14915-14924

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Modeling familial Danish dementia in mice supports the concept of the amyloid hypothesis of Alzheimer's disease

3 August 2017

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BRI3 inhibits amyloid precursor protein processing in a mechanistically distinct manner from its homologue dementia gene BRI2

7 July 2018

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7 July 2018

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7 July 2018

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26 October 2018

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26 October 2018

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The familial dementia BRI2 gene binds the Alzheimer gene amyloid-beta precursor protein and inhibits amyloid-beta production

26 October 2018

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12 December 2020

BRI2 interacts with amyloid precursor protein (APP) and regulates amyloid beta (Abeta) production

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12 December 2020

Presenilins are essential for regulating neurotransmitter release

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12 December 2020

Maturation of BRI2 generates a specific inhibitor that reduces APP processing at the plasma membrane and in endocytic vesicles

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12 December 2020

Danish dementia mice suggest that loss of function and not the amyloid cascade causes synaptic plasticity and memory deficits

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12 December 2020

10.1523/JNEUROSCI.3917-10.2010

Identifiers

DOI

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3 August 2017

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3 August 2017

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