BRI2 inhibits amyloid beta-peptide precursor protein processing by interfering with the docking of secretases to the substrate. (Q37352319)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18753367%20AND%20SRC:MED&resulttype=core&format=json

13 January 2020

title

BRI2 inhibits amyloid beta-peptide precursor protein processing by interfering with the docking of secretases to the substrate (English)

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13 January 2020

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13 January 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18753367%20AND%20SRC:MED&resulttype=core&format=json

13 January 2020

Shuji Matsuda

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13 January 2020

Luca Giliberto

series ordinal

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13 January 2020

Yukiko Matsuda

series ordinal

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13 January 2020

Eileen M McGowan

series ordinal

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13 January 2020

language of work or name

English

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publication date

1 August 2008

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13 January 2020

published in

Journal of Neuroscience

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13 January 2020

volume

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13 January 2020

issue

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13 January 2020

page(s)

8668-8676

1 reference

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BRI2 (ITM2b) inhibits Abeta deposition in vivo

13 January 2020

cites work

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6 September 2017

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6 September 2017

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6 September 2017

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BRI2 interacts with amyloid precursor protein (APP) and regulates amyloid beta (Abeta) production

6 September 2017

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The familial dementia BRI2 gene binds the Alzheimer gene amyloid-beta precursor protein and inhibits amyloid-beta production

6 September 2017

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6 September 2017

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Cleavage of amyloid-beta precursor protein and amyloid-beta precursor-like protein by BACE 1

6 September 2017

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Axonal transport of British and Danish amyloid peptides via secretory vesicles

6 September 2017

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Expression of BRI, the normal precursor of the amyloid protein of familial British dementia, in human brain

6 September 2017

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Gadd45 beta mediates the protective effects of CD40 costimulation against Fas-induced apoptosis

6 September 2017

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Notch and Presenilin: regulated intramembrane proteolysis links development and degeneration.

6 September 2017

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Aph-1, Pen-2, and Nicastrin with Presenilin generate an active gamma-Secretase complex

6 September 2017

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Processing of beta-amyloid precursor-like protein-1 and -2 by gamma-secretase regulates transcription

6 September 2017

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Sporadic and familial cerebral amyloid angiopathies.

6 September 2017

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Deciphering the genetic basis of Alzheimer's disease

6 September 2017

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The gamma-secretase-generated intracellular domain of beta-amyloid precursor protein binds Numb and inhibits Notch signaling

6 September 2017

1 reference

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gamma-Secretase, Notch, Abeta and Alzheimer's disease: where do the presenilins fit in?

6 September 2017

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A physiologic signaling role for the gamma -secretase-derived intracellular fragment of APP.

6 September 2017

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A transcriptionally [correction of transcriptively] active complex of APP with Fe65 and histone acetyltransferase Tip60

6 September 2017

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Nicastrin modulates presenilin-mediated notch/glp-1 signal transduction and betaAPP processing

6 September 2017

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A decamer duplication in the 3' region of the BRI gene originates an amyloid peptide that is associated with dementia in a Danish kindred

6 September 2017

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Furin mediates enhanced production of fibrillogenic ABri peptides in familial British dementia

6 September 2017

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6 September 2017

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A stop-codon mutation in the BRI gene associated with familial British dementia

6 September 2017

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6 September 2017

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6 September 2017

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14 September 2017

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Nicastrin functions as a gamma-secretase-substrate receptor

26 June 2018

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2 September 2018

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2 September 2018

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Early-onset amyloid deposition and cognitive deficits in transgenic mice expressing a double mutant form of amyloid precursor protein 695.

2 September 2018

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Contact-dependent inhibition of cortical neurite growth mediated by notch signaling

2 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18753367

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1523/JNEUROSCI.2094-08.2008

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18753367%20AND%20SRC:MED&resulttype=core&format=json

13 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18753367%20AND%20SRC:MED&resulttype=core&format=json

13 January 2020

PubMed publication ID

18753367

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18753367%20AND%20SRC:MED&resulttype=core&format=json