Host and viral determinants for MxB restriction of HIV-1 infection (Q34422979)

25348155

2 August 2017

title

Host and viral determinants for MxB restriction of HIV-1 infection (English)

1 reference

2 August 2017

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25348155%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

Alan Engelman

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7 June 2020

Erik Serrao

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7 June 2020

Weifeng Wang

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7 June 2020

Parmit Kumar Singh

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7 June 2020

Henry L Levin

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7 June 2020

language of work or name

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25 October 2014

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2 August 2017

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7 June 2020

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7 June 2020

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Creative Commons Attribution 4.0 International

7 June 2020

start time

25 October 2014

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April 2022 Public Data File from Crossref

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cites work

Structural insight into HIV-1 restriction by MxB.

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MxB binds to the HIV-1 core and prevents the uncoating process of HIV-1

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Transfer of the amino-terminal nuclear envelope targeting domain of human MX2 converts MX1 into an HIV-1 resistance factor

6 July 2018

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6 July 2018

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6 July 2018

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Nucleoporin NUP153 phenylalanine-glycine motifs engage a common binding pocket within the HIV-1 capsid protein to mediate lentiviral infectivity

6 July 2018

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The interferon-inducible MxB protein inhibits HIV-1 infection.

6 July 2018

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6 July 2018

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6 July 2018

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An evolutionary perspective on the broad antiviral specificity of MxA

6 July 2018

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Nup153 and Nup98 bind the HIV-1 core and contribute to the early steps of HIV-1 replication.

6 July 2018

1 reference

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6 July 2018

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TNPO3 protects HIV-1 replication from CPSF6-mediated capsid stabilization in the host cell cytoplasm.

6 July 2018

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Differential effects of human immunodeficiency virus type 1 capsid and cellular factors nucleoporin 153 and LEDGF/p75 on the efficiency and specificity of viral DNA integration

6 July 2018

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Evolution-guided identification of antiviral specificity determinants in the broadly acting interferon-induced innate immunity factor MxA.

6 July 2018

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HRP2 determines the efficiency and specificity of HIV-1 integration in LEDGF/p75 knockout cells but does not contribute to the antiviral activity of a potent LEDGF/p75-binding site integrase inhibitor

6 July 2018

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6 July 2018

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Correlation of recombinant integrase activity and functional preintegration complex formation during acute infection by replication-defective integrase mutant human immunodeficiency virus

6 July 2018

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HIV-1 capsid-cyclophilin interactions determine nuclear import pathway, integration targeting and replication efficiency

6 July 2018

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Structure of myxovirus resistance protein a reveals intra- and intermolecular domain interactions required for the antiviral function

6 July 2018

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Stalk Domain of the Dynamin-like MxA GTPase Protein Mediates Membrane Binding and Liposome Tubulation via the Unstructured L4 Loop

6 July 2018

1 reference

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Vpx relieves inhibition of HIV-1 infection of macrophages mediated by the SAMHD1 protein

6 July 2018

1 reference

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Determinants of the Higher Order Association of the Restriction Factor TRIM5α and Other Tripartite Motif (TRIM) Proteins

6 July 2018

1 reference

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SAMHD1 is the dendritic- and myeloid-cell-specific HIV-1 restriction factor counteracted by Vpx

6 July 2018

1 reference

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The requirement for nucleoporin NUP153 during human immunodeficiency virus type 1 infection is determined by the viral capsid.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4213484

A diverse range of gene products are effectors of the type I interferon antiviral response

6 July 2018

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HIV integration targeting: a pathway involving Transportin-3 and the nuclear pore protein RanBP2

6 July 2018

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Structural basis of oligomerization in the stalk region of dynamin-like MxA

6 July 2018

1 reference

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Lens epithelium-derived growth factor fusion proteins redirect HIV-1 DNA integration

6 July 2018

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6 July 2018

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The SET complex acts as a barrier to autointegration of HIV-1

6 July 2018

1 reference

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Biochemical characterization of a recombinant TRIM5alpha protein that restricts human immunodeficiency virus type 1 replication.

6 July 2018

1 reference

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The interferon-induced protein BST-2 restricts HIV-1 release and is downregulated from the cell surface by the viral Vpu protein

6 July 2018

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Tetherin inhibits retrovirus release and is antagonized by HIV-1 Vpu

6 July 2018

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6 July 2018

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Retroviral DNA integration: viral and cellular determinants of target-site selection

6 July 2018

1 reference

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Dnm1 forms spirals that are structurally tailored to fit mitochondria

6 July 2018

1 reference

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Macrophage tropism of HIV-1 depends on efficient cellular dNTP utilization by reverse transcriptase

6 July 2018

1 reference

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Cyclophilin A retrotransposition into TRIM5 explains owl monkey resistance to HIV-1

6 July 2018

1 reference

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Inhibition of nuclear import and cell-cycle progression by mutated forms of the dynamin-like GTPase MxB

6 July 2018

1 reference

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Capsid is a dominant determinant of retrovirus infectivity in nondividing cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4213484

The cytoplasmic body component TRIM5alpha restricts HIV-1 infection in Old World monkeys

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4213484

Simian virus 40-based replication of catalytically inactive human immunodeficiency virus type 1 integrase mutants in nonpermissive T cells and monocyte-derived macrophages

6 July 2018

1 reference

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Analysis of early human immunodeficiency virus type 1 DNA synthesis by use of a new sensitive assay for quantifying integrated provirus

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4213484

Human immunodeficiency virus type 1 nucleocapsid zn(2+) fingers are required for efficient reverse transcription, initial integration processes, and protection of newly synthesized viral DNA.

6 July 2018

1 reference

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Visualization of the intracellular behavior of HIV in living cells

6 July 2018

1 reference

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HIV-1 integration in the human genome favors active genes and local hotspots

6 July 2018

1 reference

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Isolation of a human gene that inhibits HIV-1 infection and is suppressed by the viral Vif protein

6 July 2018

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The human genome browser at UCSC

6 July 2018

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BLAT—The BLAST-Like Alignment Tool

6 July 2018

1 reference

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The antiviral dynamin family member, MxA, tubulates lipids and localizes to the smooth endoplasmic reticulum

6 July 2018

1 reference

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Role of the non-homologous DNA end joining pathway in the early steps of retroviral infection

6 July 2018

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A quantitative assay for HIV DNA integration in vivo

6 July 2018

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Characterization of intracellular reverse transcription complexes of human immunodeficiency virus type 1.

6 July 2018

1 reference

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Nuclear Cotransport Mechanism of Cytoplasmic Human MxB Protein

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4213484

Human MxB protein, an interferon-alpha-inducible GTPase, contains a nuclear targeting signal and is localized in the heterochromatin region beneath the nuclear envelope

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4213484

Human immunodeficiency virus type 1 integrase: effects of mutations on viral ability to integrate, direct viral gene expression from unintegrated viral DNA templates, and sustain viral propagation in primary cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4213484

Analysis of human immunodeficiency virus type 1 integrase mutants

6 July 2018

1 reference

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Multiple effects of mutations in human immunodeficiency virus type 1 integrase on viral replication

6 July 2018

1 reference

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Nucleotide sequence of cloned unintegrated avian sarcoma virus DNA: viral DNA contains direct and inverted repeats similar to those in transposable elements

6 July 2018

1 reference

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Molecular characterization of human immunodeficiency virus type 1 cloned directly from uncultured human brain tissue: identification of replication-competent and -defective viral genomes

6 July 2018

1 reference

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Efficacy and safety analyses of a recombinant human immunodeficiency virus type 1 derived vector system

6 July 2018

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Crossref

https://api.crossref.org/works/10.1186%2FS12977-014-0090-Z

Quantitative analysis of HIV-1 preintegration complexes

21 January 2018

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10.1186/S12977-014-0090-Z

21 January 2018

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DOI

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7 June 2020

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7 June 2020

25348155

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