Structural insight into HIV-1 restriction by MxB. (Q34615762)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25312384%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

title

Structural insight into HIV-1 restriction by MxB (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25312384%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25312384%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25312384%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

Frances Joan D Alvarez

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25312384%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

Jennifer L Fribourgh

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25312384%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

Brady J Summers

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25312384%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

Tamaria G Dewdney

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25312384%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

Christopher Aiken

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25312384%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

Peijun Zhang

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25312384%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

Alan Engelman

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25312384%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

Yong Xiong

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25312384%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

publication date

9 October 2014

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25312384%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25312384%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

volume

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25312384%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

issue

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25312384%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

page(s)

627-638

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25312384%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

21 February 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4252739/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

MxB binds to the HIV-1 core and prevents the uncoating process of HIV-1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4252739

Transfer of the amino-terminal nuclear envelope targeting domain of human MX2 converts MX1 into an HIV-1 resistance factor

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4252739

Host and viral determinants of Mx2 antiretroviral activity

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4252739

HIV-1 uncoating: connection to nuclear entry and regulation by host proteins

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4252739

Nucleoporin NUP153 phenylalanine-glycine motifs engage a common binding pocket within the HIV-1 capsid protein to mediate lentiviral infectivity

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4252739

MX2 is an interferon-induced inhibitor of HIV-1 infection

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4252739

Viral and cellular requirements for the nuclear entry of retroviral preintegration nucleoprotein complexes

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4252739

The interferon-inducible MxB protein inhibits HIV-1 infection.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4252739

Human MX2 is an interferon-induced post-entry inhibitor of HIV-1 infection

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4252739

CPSF6 Defines a Conserved Capsid Interface that Modulates HIV-1 Replication

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4252739

HIV-1 capsid-cyclophilin interactions determine nuclear import pathway, integration targeting and replication efficiency

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4252739

Structure of myxovirus resistance protein a reveals intra- and intermolecular domain interactions required for the antiviral function

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4252739

Structure of the MxA stalk elucidates the assembly of ring-like units of an antiviral module

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4252739

TRIM5 is an innate immune sensor for the retrovirus capsid lattice

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4252739

Human MxA Protein: An Interferon-Induced Dynamin-Like GTPase with Broad Antiviral Activity

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4252739

Dynamin-like MxA GTPase: structural insights into oligomerization and implications for antiviral activity

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4252739

Structural basis of oligomerization in the stalk region of dynamin-like MxA

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4252739

Flexible use of nuclear import pathways by HIV-1.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4252739

PHENIX: a comprehensive Python-based system for macromolecular structure solution

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4252739

X-ray structures of the hexameric building block of the HIV capsid

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4252739

Phasercrystallographic software

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4252739

Specific recognition and accelerated uncoating of retroviral capsids by the TRIM5alpha restriction factor

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4252739

Coot: model-building tools for molecular graphics

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4252739

Refinement of macromolecular structures by the maximum-likelihood method

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4252739

The CCP4 suite: programs for protein crystallography

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4252739

Inhibition of nuclear import and cell-cycle progression by mutated forms of the dynamin-like GTPase MxB

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4252739

Antivirally active MxA protein sequesters La Crosse virus nucleocapsid protein into perinuclear complexes

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4252739

Self-assembly of human MxA GTPase into highly ordered dynamin-like oligomers

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4252739

An approach to multi-copy search in molecular replacement

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4252739

Structure of human guanylate-binding protein 1 representing a unique class of GTP-binding proteins

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4252739

Intramolecular backfolding of the carboxyl-terminal end of MxA protein is a prerequisite for its oligomerization

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4252739

Human MxA protein protects mice lacking a functional alpha/beta interferon system against La crosse virus and other lethal viral infections

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4252739

Interferon-induced human MxA GTPase blocks nuclear import of Thogoto virus nucleocapsids

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4252739

GTP-bound human MxA protein interacts with the nucleocapsids of Thogoto virus (Orthomyxoviridae).

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4252739

Nuclear Cotransport Mechanism of Cytoplasmic Human MxB Protein

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4252739

Human MxB protein, an interferon-alpha-inducible GTPase, contains a nuclear targeting signal and is localized in the heterochromatin region beneath the nuclear envelope

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4252739

Mx proteins: GTPases involved in the interferon-induced antiviral state

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4252739

cDNA structures and regulation of two interferon-induced human Mx proteins

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4252739

Interferon-induced Mx proteins form oligomers and contain a putative leucine zipper

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4252739

In vivo functions of CPSF6 for HIV-1 as revealed by HIV-1 capsid evolution in HLA-B27-positive subjects

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4252739

Electron density sharpening as a general technique in crystallographic studies

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4252739

A novel inhibitor-binding site on the HIV-1 capsid N-terminal domain leads to improved crystallization via compound-mediated dimerization

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4252739

Missorting of LaCrosse virus nucleocapsid protein by the interferon-induced MxA GTPase involves smooth ER membranes

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4252739

Unexpected structural requirements for GTPase activity of the interferon-induced MxA protein.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4252739

10.1016/J.CHOM.2014.09.021

26 October 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25312384%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25312384%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

PubMed publication ID

25312384

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25312384%20AND%20SRC:MED&resulttype=core&format=json