Exogenous IFN-gamma ex vivo shapes the alloreactive T-cell repertoire by inhibition of Th17 responses and generation of functional Foxp3+ regulatory T cells (Q34333949)

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English	Exogenous IFN-gamma ex vivo shapes the alloreactive T-cell repertoire by inhibition of Th17 responses and generation of functional Foxp3+ regulatory T cells	scientific article

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scholarly article

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Europe PubMed Central

PubMed publication ID

1 August 2017

Exogenous IFN-gamma ex vivo shapes the alloreactive T-cell repertoire by inhibition of Th17 responses and generation of functional Foxp3+ regulatory T cells (English)

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

author name string

Gang Feng

1

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Europe PubMed Central

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1 August 2017

Wenda Gao

2

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Europe PubMed Central

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1 August 2017

Terry B Strom

3

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Europe PubMed Central

PubMed publication ID

1 August 2017

Mohamed Oukka

4

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Europe PubMed Central

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1 August 2017

Ross S Francis

5

1 reference

Europe PubMed Central

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1 August 2017

Kathryn J Wood

6

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Europe PubMed Central

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1 August 2017

Andrew Bushell

7

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Europe PubMed Central

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1 August 2017

language of work or name

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publication date

1 September 2008

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Europe PubMed Central

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1 August 2017

European Journal of Immunology

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Europe PubMed Central

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1 August 2017

38

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Europe PubMed Central

PubMed publication ID

1 August 2017

9

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

2512-2527

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

Antagonistic nature of T helper 1/2 developmental programs in opposing peripheral induction of Foxp3+ regulatory T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2988413

6 July 2018

Nitric oxide induces CD4+CD25+ Foxp3 regulatory T cells from CD4+CD25 T cells via p53, IL-2, and OX40

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2988413

6 July 2018

IFN-gamma acts directly on activated CD4+ T cells during mycobacterial infection to promote apoptosis by inducing components of the intracellular apoptosis machinery and by inducing extracellular proapoptotic signals

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2988413

6 July 2018

Genome-wide profiles of STAT1 DNA association using chromatin immunoprecipitation and massively parallel sequencing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2988413

6 July 2018

IFN-gamma mediates CD4+ T-cell loss and impairs secondary antitumor responses after successful initial immunotherapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2988413

6 July 2018

Nonredundant roles for Stat5a/b in directly regulating Foxp3

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2988413

6 July 2018

IL-17 family cytokines and the expanding diversity of effector T cell lineages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2988413

6 July 2018

Role of IFN-gamma in induction of Foxp3 and conversion of CD4+ CD25- T cells to CD4+ Tregs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2988413

6 July 2018

Interleukin 27 limits autoimmune encephalomyelitis by suppressing the development of interleukin 17-producing T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2988413

6 July 2018

TGF-beta-mediated suppression by CD4+CD25+ T cells is facilitated by CTLA-4 signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2988413

6 July 2018

Anti-IL-23 therapy inhibits multiple inflammatory pathways and ameliorates autoimmune encephalomyelitis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2988413

6 July 2018

Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2988413

6 July 2018

Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2988413

6 July 2018

A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2988413

6 July 2018

Regulation of immune responses by L-arginine metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2988413

6 July 2018

TGF-beta1 maintains suppressor function and Foxp3 expression in CD4+CD25+ regulatory T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2988413

6 July 2018

IDO expression by dendritic cells: tolerance and tryptophan catabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2988413

6 July 2018

Loss of T-bet, but not STAT1, prevents the development of experimental autoimmune encephalomyelitis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2988413

6 July 2018

Impaired development of CD4+ CD25+ regulatory T cells in the absence of STAT1: increased susceptibility to autoimmune disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2988413

6 July 2018

Effector mechanisms in transplant rejection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2988413

6 July 2018

Regulatory T cells in transplantation tolerance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2988413

6 July 2018

Interferon gamma is required for activation-induced death of T lymphocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2988413

6 July 2018

SB-431542 is a potent and specific inhibitor of transforming growth factor-beta superfamily type I activin receptor-like kinase (ALK) receptors ALK4, ALK5, and ALK7

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2988413

6 July 2018

Multiple pathways to allograft rejection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2988413

6 July 2018

Impaired response to interferon-gamma in activated macrophages due to tyrosine nitration of STAT1 by endogenous nitric oxide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2988413

6 July 2018

Failure to suppress the expansion of the activated CD4 T cell population in interferon gamma-deficient mice leads to exacerbation of experimental autoimmune encephalomyelitis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2988413

6 July 2018

Interferon gamma eliminates responding CD4 T cells during mycobacterial infection by inducing apoptosis of activated CD4 T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2988413

6 July 2018

Interleukin 12 protects from a T helper type 1-mediated autoimmune disease, experimental autoimmune uveitis, through a mechanism involving interferon gamma, nitric oxide, and apoptosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2988413

6 July 2018

Nitric oxide regulates Th1 cell development through the inhibition of IL-12 synthesis by macrophages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2988413

6 July 2018

Immune suppression by recombinant interleukin (rIL)-12 involves interferon gamma induction of nitric oxide synthase 2 (iNOS) activity: inhibitors of NO generation reveal the extent of rIL-12 vaccine adjuvant effect

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2988413

6 July 2018

Long-term survival of skin allografts induced by donor splenocytes and anti-CD154 antibody in thymectomized mice requires CD4(+) T cells, interferon-gamma, and CTLA4.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2988413

6 July 2018

Cytokines induce the development of functionally heterogeneous T helper cell subsets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2988413

6 July 2018

High susceptibility to collagen-induced arthritis in mice lacking IFN-gamma receptors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2988413

6 July 2018

Cellular responses to interferon-gamma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2988413

6 July 2018

A direct role for IFN-gamma in regulation of Th1 cell development.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2988413

6 July 2018

Targeted disruption of the mouse Stat1 gene results in compromised innate immunity to viral disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2988413

6 July 2018

Targeted disruption of the Stat1 gene in mice reveals unexpected physiologic specificity in the JAK-STAT signaling pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2988413

6 July 2018

Altered immune responses in mice lacking inducible nitric oxide synthase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2988413

6 July 2018

Interferon gamma plays a critical role in induced cell death of effector T cell: a possible third mechanism of self-tolerance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2988413

6 July 2018

Induction of tolerance in peripheral T cells with monoclonal antibodies.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2988413

6 July 2018

Generation of large numbers of dendritic cells from mouse bone marrow cultures supplemented with granulocyte/macrophage colony-stimulating factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2988413

6 July 2018

The presence of interleukin 4 during in vitro priming determines the lymphokine-producing potential of CD4+ T cells from T cell receptor transgenic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2988413

6 July 2018

Interferon γ: a crucial role in the function of induced regulatory T cells in vivo

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838411

21 January 2018

CD40Ig treatment results in allograft acceptance mediated by CD8CD45RC T cells, IFN-gamma, and indoleamine 2,3-dioxygenase

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838411

21 January 2018

Self-limitation of Th1-mediated inflammation by IFN-gamma.

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838411

21 January 2018

IFN-gamma production by alloantigen-reactive regulatory T cells is important for their regulatory function in vivo

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838411

21 January 2018

CTLA-4-Ig regulates tryptophan catabolism in vivo.

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838411

21 January 2018

Generation ex vivo of TGF-beta-producing regulatory T cells from CD4+CD25- precursors.

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838411

21 January 2018

Transforming growth factor-beta: taking control of T cells' life and death

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838411

21 January 2018

Requirement for T-cell apoptosis in the induction of peripheral transplantation tolerance.

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838411

21 January 2018

Blocking both signal 1 and signal 2 of T-cell activation prevents apoptosis of alloreactive T cells and induction of peripheral allograft tolerance

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838411

21 January 2018

Rapamycin selectively expands CD4+CD25+FoxP3+ regulatory T cells.

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838411

21 January 2018

CD4+ regulatory T cells are spared from deletion by antilymphocyte serum, a polyclonal anti-T cell antibody.

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838411

21 January 2018

When ligand becomes receptor--tolerance via B7 signaling on DCs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2988413

27 October 2018

IFN-gamma is critical for long-term allograft survival induced by blocking the CD28 and CD40 ligand T cell costimulation pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2988413

27 October 2018

Mice with a disrupted IFN-gamma gene are susceptible to the induction of experimental autoimmune encephalomyelitis (EAE).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2988413

27 October 2018

Macrophages driven to a novel state of activation have anti-inflammatory properties in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/18792404

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IFN-gamma is critical to the control of murine autoimmune encephalomyelitis and regulates both in the periphery and in the target tissue: a possible role for nitric oxide

1 reference

https://pubmed.ncbi.nlm.nih.gov/18792404

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Susceptibility to collagen-induced arthritis: cytokine-mediated regulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/18792404

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunobiology of allograft rejection in the absence of IFN-gamma: CD8+ effector cells develop independently of CD4+ cells and CD40-CD40 ligand interactions

1 reference

https://pubmed.ncbi.nlm.nih.gov/18792404

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The infusion of ex vivo activated and expanded CD4(+)CD25(+) immune regulatory cells inhibits graft-versus-host disease lethality

1 reference

https://pubmed.ncbi.nlm.nih.gov/18792404

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nitric oxide suppresses human T lymphocyte proliferation through IFN-gamma-dependent and IFN-gamma-independent induction of apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/18792404

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inducing and expanding regulatory T cell populations by foreign antigen

1 reference

https://pubmed.ncbi.nlm.nih.gov/18792404

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Yin and Yang of IFN-gamma in allograft rejection

1 reference

https://pubmed.ncbi.nlm.nih.gov/18792404

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anti-proliferative effect of IFN-gamma in immune regulation. I. IFN-gamma inhibits the proliferation of Th2 but not Th1 murine helper T lymphocyte clones

1 reference

https://pubmed.ncbi.nlm.nih.gov/18792404

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of human peripheral blood mononuclear cells by nitric oxide-generating compounds

1 reference

https://pubmed.ncbi.nlm.nih.gov/18792404

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Roles of IFN-gamma and IFN-alpha in IL-12-induced T helper cell-1 development

1 reference

https://pubmed.ncbi.nlm.nih.gov/18792404

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acute rejection of vascularized heart allografts in the absence of IFNgamma

1 reference

https://pubmed.ncbi.nlm.nih.gov/18792404

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Contrasting effects of TGF-beta 1 and TNF-alpha on the development of dendritic cells from progenitors in mouse bone marrow

1 reference

https://pubmed.ncbi.nlm.nih.gov/18792404

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Accelerated collagen-induced arthritis in IFN-gamma receptor-deficient mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/18792404

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of tolerance by IL-10-treated dendritic cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/18792404

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nitric oxide synthase plays a signaling role in TCR-triggered apoptotic death

1 reference

https://pubmed.ncbi.nlm.nih.gov/18792404

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1002/EJI.200838411

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

ResearchGate publication ID

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