Impaired development of CD4+ CD25+ regulatory T cells in the absence of STAT1: increased susceptibility to autoimmune disease (Q24816789)

4 July 2017

title

Impaired development of CD4+ CD25+ regulatory T cells in the absence of STAT1: increased susceptibility to autoimmune disease (English)

1 reference

4 July 2017

1 reference

Takeaki Nishibori

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4 July 2017

Yoshinari Tanabe

series ordinal

1 reference

4 July 2017

Leon Su

series ordinal

1 reference

4 July 2017

Michael David

series ordinal

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4 July 2017

language of work or name

English

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publication date

29 December 2003

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Journal of Experimental Medicine

4 July 2017

published in

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4 July 2017

volume

199

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4 July 2017

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4 July 2017

page(s)

25-34

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Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases

4 July 2017

cites work

1 reference

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B7/CD28 costimulation is essential for the homeostasis of the CD4+CD25+ immunoregulatory T cells that control autoimmune diabetes

7 April 2017

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CD4+CD25+ immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production

7 April 2017

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Targeted disruption of the mouse Stat1 gene results in compromised innate immunity to viral disease

7 April 2017

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Targeted disruption of the Stat1 gene in mice reveals unexpected physiologic specificity in the JAK-STAT signaling pathway

7 April 2017

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Transcriptional responses to polypeptide ligands: the JAK-STAT pathway

7 April 2017

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CD4(+)CD25(+) immunoregulatory T cells: gene expression analysis reveals a functional role for the glucocorticoid-induced TNF receptor

7 April 2017

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An integrative model of regulation centered on recognition of TCR peptide/MHC complexes

28 September 2017

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Regulatory T cells in the control of immune pathology.

28 September 2017

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Control of autoimmunity by regulatory T cells

28 September 2017

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Interferons alpha and beta as immune regulators--a new look

28 September 2017

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Certified professionals: CD4(+)CD25(+) suppressor T cells

28 September 2017

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Regulatory T cells: key controllers of immunologic self-tolerance

28 September 2017

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28 September 2017

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STAT1 affects lymphocyte survival and proliferation partially independent of its role downstream of IFN-gamma

28 September 2017

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Interferon beta in multiple sclerosis: is IL-12 suppression the key?

28 September 2017

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Suppressor effector function of CD4+CD25+ immunoregulatory T cells is antigen nonspecific

28 September 2017

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Assessment of animal models for MS and demyelinating disease in the design of rational therapy

28 September 2017

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CD4(+) T cells prevent spontaneous experimental autoimmune encephalomyelitis in anti-myelin basic protein T cell receptor transgenic mice

28 September 2017

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An interleukin (IL)-10/IL-12 immunoregulatory circuit controls susceptibility to autoimmune disease.

28 September 2017

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Defective TNF-α-Induced Apoptosis in STAT1-Null Cells Due to Low Constitutive Levels of Caspases

28 September 2017

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Multiple sclerosis: a coordinated immunological attack against myelin in the central nervous system

28 September 2017

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Complementation of a mutant cell line: central role of the 91 kDa polypeptide of ISGF3 in the interferon-alpha and -gamma signal transduction pathways

28 September 2017

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Surface expression of alpha 4 integrin by CD4 T cells is required for their entry into brain parenchyma

28 September 2017

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Failure to suppress the expansion of the activated CD4 T cell population in interferon gamma-deficient mice leads to exacerbation of experimental autoimmune encephalomyelitis

28 September 2017

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Regulatory CD4 T cells: expression of IL-2R alpha chain, resistance to clonal deletion and IL-2 dependency

31 May 2018

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CD4+CD25+ T cells inhibit both the induction and effector function of autoreactive T cells and represent a unique lineage of immunoregulatory cells.

31 May 2018

1 reference

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CD4+ T-cell subsets in autoimmunity

31 May 2018

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Transgenic mice that express a myelin basic protein-specific T cell receptor develop spontaneous autoimmunity

31 May 2018

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Type I IFN modulates innate and specific antiviral immunity.

21 January 2018

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High incidence of spontaneous autoimmune encephalomyelitis in immunodeficient anti-myelin basic protein T cell receptor transgenic mice

21 January 2018

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Naturally anergic and suppressive CD25(+)CD4(+) T cells as a functionally and phenotypically distinct immunoregulatory T cell subpopulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20020509

CD62L is required on effector cells for local interactions in the CNS to cause myelin damage in experimental allergic encephalomyelitis

21 January 2018

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https://api.crossref.org/works/10.1084%2FJEM.20020509

IFN-gamma plays a critical down-regulatory role in the induction and effector phase of myelin oligodendrocyte glycoprotein-induced autoimmune encephalomyelitis

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/14699080

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1084/JEM.20020509

1 reference

4 July 2017

1 reference

4 July 2017

1 reference