Immune suppression by recombinant interleukin (rIL)-12 involves interferon gamma induction of nitric oxide synthase 2 (iNOS) activity: inhibitors of NO generation reveal the extent of rIL-12 vaccine adjuvant effect (Q36401702)

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English	Immune suppression by recombinant interleukin (rIL)-12 involves interferon gamma induction of nitric oxide synthase 2 (iNOS) activity: inhibitors of NO generation reveal the extent of rIL-12 vaccine adjuvant effect	scientific article

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Immune suppression by recombinant interleukin (rIL)-12 involves interferon gamma induction of nitric oxide synthase 2 (iNOS) activity: inhibitors of NO generation reveal the extent of rIL-12 vaccine adjuvant effect (English)

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

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author name string

H K Koblish

1

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

C A Hunter

2

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

M Wysocka

3

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

G Trinchieri

4

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

W M Lee

5

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Europe PubMed Central

PMC publication ID

14 August 2017

language of work or name

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publication date

1 November 1998

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Europe PubMed Central

PMC publication ID

14 August 2017

Journal of Experimental Medicine

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Europe PubMed Central

PMC publication ID

14 August 2017

188

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Europe PubMed Central

PMC publication ID

14 August 2017

9

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

1603-1610

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Phase I evaluation of intravenous recombinant human interleukin 12 in patients with advanced malignancies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212512

30 September 2017

Macrophage-derived nitric oxide regulates T cell activation via reversible disruption of the Jak3/STAT5 signaling pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212512

30 September 2017

Interleukin-12 and interleukin-18 synergistically induce murine tumor regression which involves inhibition of angiogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212512

30 September 2017

Interleukin-12 is critical for induction of nitric oxide-mediated immunosuppression following vaccination of mice with attenuated Salmonella typhimurium.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212512

30 September 2017

Nitric oxide and macrophage function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212512

30 September 2017

Role of IL12 as an anti-tumour agent: current status and future directions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212512

30 September 2017

Gene gun-mediated skin transfection with interleukin 12 gene results in regression of established primary and metastatic murine tumors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212512

30 September 2017

Mice lacking the tumour necrosis factor receptor 1 are resistant to TNF-mediated toxicity but highly susceptible to infection by Listeria monocytogenes

1 reference

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30 September 2017

Mitogen- and antigen-specific proliferation of T cells in murine toxoplasmosis is inhibited by reactive nitrogen intermediates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212512

30 September 2017

Influence of interleukin 12 on p53 peptide vaccination against established Meth A sarcoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212512

30 September 2017

Mechanism of interleukin 12-mediated toxicities during experimental viral infections: role of tumor necrosis factor and glucocorticoids

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212512

30 September 2017

Roles of gamma interferon and other cytokines in suppression of the spleen cell proliferative response to concanavalin A and toxoplasma antigen during acute toxoplasmosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212512

30 September 2017

Interleukin-12: a proinflammatory cytokine with immunoregulatory functions that bridge innate resistance and antigen-specific adaptive immunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212512

30 September 2017

Analysis of nitrate, nitrite, and [15N]nitrate in biological fluids

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212512

30 September 2017

Morphine enhances macrophage apoptosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212512

28 June 2018

Inhibition of angiogenesis in vivo by interleukin 12.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212512

28 June 2018

Role of interferon-gamma in interleukin 12-induced pathology in mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212512

28 June 2018

Studies on the role of interleukin-12 in acute murine toxoplasmosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212512

21 September 2018

Interleukin-12 is required for interferon-gamma production and lethality in lipopolysaccharide-induced shock in mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212512

21 September 2018

Trypanosoma cruzi: Tc52 released protein-induced increased expression of nitric oxide synthase and nitric oxide production by macrophages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212512

5 December 2018

Activation-induced CD4+ T cell death by apoptosis in experimental Chagas' disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212512

5 December 2018

Recombinant interleukin 12 enhances cellular immune responses to vaccination only after a period of suppression

1 reference

https://pubmed.ncbi.nlm.nih.gov/9802972

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

B7-1 and interleukin 12 synergistically induce effective antitumor immunity

1 reference

https://pubmed.ncbi.nlm.nih.gov/9802972

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IL-12 deaths: explanation and a puzzle

1 reference

https://pubmed.ncbi.nlm.nih.gov/9802972

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of angiogenesis by interleukin-12 is mediated by the interferon-inducible protein 10

1 reference

https://pubmed.ncbi.nlm.nih.gov/9802972

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tumor necrosis factor receptors (Tnfr) in mouse fibroblasts deficient in Tnfr1 or Tnfr2 are signaling competent and activate the mitogen-activated protein kinase pathway with differential kinetics

1 reference

https://pubmed.ncbi.nlm.nih.gov/9802972

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effect of interleukin 12 desensitization on the antitumor efficacy of recombinant interleukin 12

1 reference

https://pubmed.ncbi.nlm.nih.gov/9802972

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reactive nitrogen intermediates suppress the primary immunologic response to Listeria

1 reference

https://pubmed.ncbi.nlm.nih.gov/9802972

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immune response in mice that lack the interferon-gamma receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/9802972

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of IL-12 on the response and susceptibility to experimental viral infections

1 reference

https://pubmed.ncbi.nlm.nih.gov/9802972

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Macrophage-derived nitric oxide is involved in the depressed concanavalin A responsiveness of splenic lymphocytes from rats administered morphine in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/9802972

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1084/JEM.188.9.1603

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

ResearchGate publication ID

0 references

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