Ibuprofen attenuates oxidative damage through NOX2 inhibition in Alzheimer's disease (Q34306241)

1 August 2017

title

Ibuprofen attenuates oxidative damage through NOX2 inhibition in Alzheimer's disease (English)

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1 August 2017

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Brandy L Wilkinson

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1 August 2017

Paige E Cramer

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1 August 2017

Nicholas H Varvel

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1 August 2017

Erin Reed-Geaghan

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1 August 2017

Qingguang Jiang

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1 August 2017

Alison Szabo

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1 August 2017

Karl Herrup

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1 August 2017

Bruce T Lamb

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1 August 2017

Gary E Landreth

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1 August 2017

publication date

8 August 2010

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1 August 2017

published in

Neurobiology of Aging

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1 August 2017

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1 August 2017

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1 August 2017

page(s)

197.e21-32

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Formation and maintenance of Alzheimer's disease beta-amyloid plaques in the absence of microglia

1 August 2017

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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Ibuprofen suppresses plaque pathology and inflammation in a mouse model for Alzheimer's disease.

6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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Relation of NSAIDs to incident AD, change in cognitive function, and AD pathology

6 July 2018

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Cyclooxygenase-2 inhibition improves amyloid-beta-mediated suppression of memory and synaptic plasticity

28 October 2018

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Naproxen and celecoxib do not prevent AD in early results from a randomized controlled trial

28 October 2018

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Deletion of the prostaglandin E2 EP2 receptor reduces oxidative damage and amyloid burden in a model of Alzheimer's disease.

28 October 2018

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Microglial phagocytosis induced by fibrillar beta-amyloid and IgGs are differentially regulated by proinflammatory cytokines.

28 October 2018

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Nonsteroidal anti-inflammatory drugs lower Abeta42 and change presenilin 1 conformation

28 October 2018

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Lipid peroxidation and oxidative imbalance: early functional events in Alzheimer's disease.

28 October 2018

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Rofecoxib: no effect on Alzheimer's disease in a 1-year, randomized, blinded, controlled study

28 October 2018

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28 October 2018

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Anti-inflammatory drug therapy alters beta-amyloid processing and deposition in an animal model of Alzheimer's disease.

28 October 2018

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28 October 2018

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28 October 2018

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28 October 2018

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Ibuprofen effects on Alzheimer pathology and open field activity in APPsw transgenic mice

28 October 2018

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Neuropathological characterization of mutant amyloid precursor protein yeast artificial chromosome transgenic mice

28 October 2018

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A subset of NSAIDs lower amyloidogenic Abeta42 independently of cyclooxygenase activity

28 October 2018

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Increased lipid peroxidation precedes amyloid plaque formation in an animal model of Alzheimer amyloidosis.

28 October 2018

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28 October 2018

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Amyloid production and deposition in mutant amyloid precursor protein and presenilin-1 yeast artificial chromosome transgenic mice.

28 October 2018

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RNA oxidation is a prominent feature of vulnerable neurons in Alzheimer's disease.

28 October 2018

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beta-Amyloid fibrils activate parallel mitogen-activated protein kinase pathways in microglia and THP1 monocytes.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2980562

4-Hydroxynonenal-derived advanced lipid peroxidation end products are increased in Alzheimer's disease

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2980562

Widespread peroxynitrite-mediated damage in Alzheimer's disease

28 October 2018

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Amyloid fibrils activate tyrosine kinase-dependent signaling and superoxide production in microglia.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2980562

Nonsteroidal Antiinflammatory Drugs and the Risk of Alzheimer's Disease

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2980562

Roles of p38 MAPK, PKC and PI3-K in the signaling pathways of NADPH oxidase activation and phagocytosis in bovine polymorphonuclear leukocytes

28 October 2018

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12 December 2020

Fibrillar beta-amyloid-stimulated intracellular signaling cascades require Vav for induction of respiratory burst and phagocytosis in monocytes and microglia

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12 December 2020

Role of stress-activated mitogen-activated protein kinase (p38) in beta 2-integrin-dependent neutrophil adhesion and the adhesion-dependent oxidative burst

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12 December 2020

Spin trapping of ibuprofen radicals: evidence that ibuprofen is a hydroxyl radical scavenger

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12 December 2020

10.1016/J.NEUROBIOLAGING.2010.06.014

Identifiers

DOI

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1 August 2017

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1 August 2017

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