A cell surface receptor complex for fibrillar beta-amyloid mediates microglial activation. (Q40657503)

PubMed publication ID

12684452

22 September 2017

title

A cell surface receptor complex for fibrillar beta-amyloid mediates microglial activation (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6742111&resulttype=core&format=json

12 May 2020

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Maria E Bamberger

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6742111&resulttype=core&format=json

12 May 2020

Meera E Harris

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6742111&resulttype=core&format=json

12 May 2020

Douglas R McDonald

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6742111&resulttype=core&format=json

12 May 2020

Jens Husemann

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6742111&resulttype=core&format=json

12 May 2020

Gary E Landreth

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6742111&resulttype=core&format=json

12 May 2020

language of work or name

English

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publication date

1 April 2003

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PubMed publication ID

12684452

22 September 2017

published in

Journal of Neuroscience

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12 May 2020

volume

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12 May 2020

issue

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12 May 2020

page(s)

2665-2674

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The thrombospondin receptor integrin-associated protein (CD47) functionally couples to heterotrimeric Gi

12 May 2020

cites work

1 reference

12 December 2020

The amino-terminus of the amyloid-beta protein is critical for the cellular binding and consequent activation of the respiratory burst of human macrophages

1 reference

12 December 2020

beta-amyloid activates the O-2 forming NADPH oxidase in microglia, monocytes, and neutrophils. A possible inflammatory mechanism of neuronal damage in Alzheimer's disease

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12 December 2020

Proinflammatory profile of cytokine production by human monocytes and murine microglia stimulated with beta-amyloid[25-35].

1 reference

12 December 2020

Thrombospondin-1 acts via IAP/CD47 to synergize with collagen in alpha2beta1-mediated platelet activation

1 reference

12 December 2020

Integrin-associated protein stimulates alpha2beta1-dependent chemotaxis via Gi-mediated inhibition of adenylate cyclase and extracellular-regulated kinases

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12 December 2020

The betaA4 amyloid peptide complexes to and enhances the uptake of beta-very low density lipoproteins by the low density lipoprotein receptor-related protein and heparan sulfate proteoglycans pathway

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12 December 2020

Elimination of the class A scavenger receptor does not affect amyloid plaque formation or neurodegeneration in transgenic mice expressing human amyloid protein precursors

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12 December 2020

Signals leading to apoptosis-dependent inhibition of neovascularization by thrombospondin-1

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12 December 2020

Inflammatory mechanisms in Alzheimer's disease: inhibition of beta-amyloid-stimulated proinflammatory responses and neurotoxicity by PPARgamma agonists.

1 reference

12 December 2020

Amyloid beta and amylin fibrils induce increases in proinflammatory cytokine and chemokine production by THP-1 cells and murine microglia

1 reference

12 December 2020

SHPS-1 induces aggregation of Ba/F3 pro-B cells via an interaction with CD47.

1 reference

12 December 2020

Association of beta 1 integrin with focal adhesion kinase and paxillin in differentiating Schwann cells.

1 reference

12 December 2020

Inflammation and Alzheimer's disease

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12 December 2020

The Integrins α3β1and α6β1 Physically and Functionally Associate with CD36 in Human Melanoma Cells

1 reference

12 December 2020

beta-Amyloid(1-42) peptide directly modulates nicotinic receptors in the rat hippocampal slice.

1 reference

12 December 2020

beta-Amyloid stimulation of microglia and monocytes results in TNFalpha-dependent expression of inducible nitric oxide synthase and neuronal apoptosis.

1 reference

12 December 2020

Amyloid (beta)42 activates a G-protein-coupled chemoattractant receptor, FPR-like-1

1 reference

12 December 2020

Effect of lipopolysaccharide on the morphology and integrin immunoreactivity of ramified microglia in the mouse brain and in cell culture

1 reference

12 December 2020

CD36 associates with CD9 and integrins on human blood platelets

1 reference

12 December 2020

Scavenger receptor class B type I (SR-BI) mediates adhesion of neonatal murine microglia to fibrillar beta-amyloid

1 reference

12 December 2020

Integrin-associated protein (CD47) and its ligands

1 reference

12 December 2020

Antihypertensive drugs and incidence of dementia: the Rotterdam Study

1 reference

12 December 2020

Signaling networks regulating beta1 integrin-mediated adhesion of T lymphocytes to extracellular matrix.

1 reference

12 December 2020

Beta-amyloid activates the mitogen-activated protein kinase cascade via hippocampal alpha7 nicotinic acetylcholine receptors: In vitro and in vivo mechanisms related to Alzheimer's disease

1 reference

12 December 2020

Involvement of microglial receptor for advanced glycation endproducts (RAGE) in Alzheimer's disease: identification of a cellular activation mechanism.

1 reference

12 December 2020

CD36, a class B scavenger receptor, is expressed on microglia in Alzheimer's disease brains and can mediate production of reactive oxygen species in response to beta-amyloid fibrils

1 reference

12 December 2020

A CD36-initiated signaling cascade mediates inflammatory effects of beta-amyloid.

1 reference

12 December 2020

A 109-amino-acid C-terminal fragment of Alzheimer's-disease amyloid precursor protein contains a sequence, -RHDS-, that promotes cell adhesion

1 reference

12 December 2020

β-Amyloid stimulates glial cells in vitro to produce growth factors that accumulate in senile plaques in Alzheimer's disease

1 reference

12 December 2020

Tyrosine phosphorylation systems in Alzheimer's disease pathology

1 reference

12 December 2020

Membrane glycoprotein IV (CD36) is physically associated with the Fyn, Lyn, and Yes protein-tyrosine kinases in human platelets

1 reference

12 December 2020

Assembly and aggregation properties of synthetic Alzheimer's A4/beta amyloid peptide analogs

1 reference

12 December 2020

Microassays for superoxide and hydrogen peroxide production and nitroblue tetrazolium reduction using an enzyme immunoassay microplate reader

1 reference

12 December 2020

Stimulation of the scavenger receptor on monocytes-macrophages evokes release of arachidonic acid metabolites and reduced oxygen species

1 reference

12 December 2020

Activation of macrophages by Alzheimer beta amyloid peptide

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12 December 2020

1 reference

12 December 2020

Recombinant GST/CD36 fusion proteins define a thrombospondin binding domain. Evidence for a single calcium-dependent binding site on CD36.

1 reference

12 December 2020

Integrin-mediated tyrosine phosphorylation and cytokine message induction in monocytic cells. A possible signaling role for the Syk tyrosine kinase.

1 reference

12 December 2020

Diversity of function is inherent in matricellular proteins: an appraisal of thrombospondin 1

1 reference

12 December 2020

Activation of microglial cells by beta-amyloid protein and interferon-gamma.

1 reference

12 December 2020

Nonsteroidal anti-inflammatory drugs in Alzheimer's disease.

1 reference

12 December 2020

Bordetella pertussis filamentous hemagglutinin interacts with a leukocyte signal transduction complex and stimulates bacterial adherence to monocyte CR3 (CD11b/CD18).

1 reference

12 December 2020

Structures and functions of multiligand lipoprotein receptors: macrophage scavenger receptors and LDL receptor-related protein (LRP).

1 reference

12 December 2020

Beta-amyloid neurotoxicity requires fibril formation and is inhibited by congo red.

1 reference

12 December 2020

Alzheimer beta-amyloid peptide 25-35: electrostatic interactions with phospholipid membranes.

1 reference

12 December 2020

Neurodegeneration induced by beta-amyloid peptides in vitro: the role of peptide assembly state

1 reference

12 December 2020

Integrin-associated protein is a receptor for the C-terminal domain of thrombospondin

1 reference

12 December 2020

Inhibition of macrophage scavenger receptor activity by tumor necrosis factor-alpha is transcriptionally and post-transcriptionally regulated

1 reference

12 December 2020

The serpin-enzyme complex receptor recognizes soluble, nontoxic amyloid-beta peptide but not aggregated, cytotoxic amyloid-beta peptide

1 reference

12 December 2020

Mechanisms of pertussis toxin-induced myelomonocytic cell adhesion: role of Mac-1(CD11b/CD18) and urokinase receptor (CD87)

1 reference

12 December 2020

beta-Amyloid induces increased release of interleukin-1 beta from lipopolysaccharide-activated human monocytes

1 reference

12 December 2020

The role of anti-inflammatory drugs in the prevention and treatment of Alzheimer's disease

1 reference

12 December 2020

RAGE and amyloid-beta peptide neurotoxicity in Alzheimer's disease

1 reference

12 December 2020

Scavenger receptor-mediated adhesion of microglia to beta-amyloid fibrils

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12 December 2020

Beta-amyloid (25-35) peptide and IFN-gamma synergistically induce the production of the chemotactic cytokine MCP-1/JE in monocytes and microglial cells.

1 reference

12 December 2020

Microglial cells internalize aggregates of the Alzheimer's disease amyloid beta-protein via a scavenger receptor

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12 December 2020

Amyloid fibrils activate tyrosine kinase-dependent signaling and superoxide production in microglia.

1 reference

12 December 2020

Risk of Alzheimer's disease and duration of NSAID use.

1 reference

12 December 2020

beta-Amyloid-induced IL-1 beta release from an activated human monocyte cell line is calcium- and G-protein-dependent

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12 December 2020

Thrombspondin acts via integrin-associated protein to activate the platelet integrin alphaIIbbeta3

1 reference

12 December 2020

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1 reference

12 December 2020

The thrombospondin receptor CD47 (IAP) modulates and associates with alpha2 beta1 integrin in vascular smooth muscle cells

1 reference

12 December 2020

Nonsteroidal anti-inflammatory drug use and Alzheimer-type pathology in aging

1 reference

12 December 2020

PPARgamma promotes monocyte/macrophage differentiation and uptake of oxidized LDL

1 reference

12 December 2020

The alpha5beta1 integrin mediates elimination of amyloid-beta peptide and protects against apoptosis

1 reference

12 December 2020

beta-Amyloid fibrils activate parallel mitogen-activated protein kinase pathways in microglia and THP1 monocytes.

1 reference

12 December 2020

Macrophage colony-stimulating factor augments beta-amyloid-induced interleukin-1, interleukin-6, and nitric oxide production by microglial cells

1 reference

12 December 2020

Amyloid-beta induces chemokine secretion and monocyte migration across a human blood--brain barrier model

1 reference

12 December 2020

Integrins take partners: cross-talk between integrins and other membrane receptors

1 reference

12 December 2020

The HHQK domain of beta-amyloid provides a structural basis for the immunopathology of Alzheimer's disease

1 reference

12 December 2020

Complementary roles for scavenger receptor A and CD36 of human monocyte-derived macrophages in adhesion to surfaces coated with oxidized low-density lipoproteins and in secretion of H2O2.

1 reference

12 December 2020

Integrin-associated protein is a ligand for the P84 neural adhesion molecule

1 reference

12 December 2020

Identification of microglial signal transduction pathways mediating a neurotoxic response to amyloidogenic fragments of beta-amyloid and prion proteins

1 reference

12 December 2020

10.1523/JNEUROSCI.23-07-02665.2003

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6742111&resulttype=core&format=json

12 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6742111&resulttype=core&format=json

12 May 2020

PubMed publication ID

12684452

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6742111&resulttype=core&format=json