Cooperation of tumor-derived HBx mutants and p53-249(ser) mutant in regulating cell proliferation, anchorage-independent growth and aneuploidy in a telomerase-immortalized normal human hepatocyte-derived cell line (Q34177169)

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English	Cooperation of tumor-derived HBx mutants and p53-249(ser) mutant in regulating cell proliferation, anchorage-independent growth and aneuploidy in a telomerase-immortalized normal human hepatocyte-derived cell line	scientific article

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scholarly article

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Europe PubMed Central

PubMed publication ID

31 July 2017

Cooperation of tumor-derived HBx mutants and p53-249(ser) mutant in regulating cell proliferation, anchorage-independent growth and aneuploidy in a telomerase-immortalized normal human hepatocyte-derived cell line (English)

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31 July 2017

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S. Perwez Hussain

6

object named as

S Perwez Hussain

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31 July 2017

author name string

Weidong Jiang

1

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31 July 2017

Xin Wei Wang

2

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31 July 2017

Tamar Unger

3

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31 July 2017

Marshonna Forgues

4

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31 July 2017

Jin Woo Kim

5

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31 July 2017

Elise Bowman

7

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31 July 2017

Elisa A Spillare

8

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31 July 2017

Michael M Lipsky

9

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31 July 2017

Jeanne M Meck

10

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31 July 2017

Luciane R Cavalli

11

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31 July 2017

Bassem R Haddad

12

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31 July 2017

Curtis C Harris

13

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31 July 2017

language of work or name

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publication date

1 September 2010

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31 July 2017

International Journal of Cancer

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31 July 2017

127

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31 July 2017

5

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31 July 2017

1011-1020

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31 July 2017

Premature cell cycle entry induced by hepatitis B virus regulatory HBx protein during compensatory liver regeneration

1 reference

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5 July 2018

Hepatitis B virus X protein affects S phase progression leading to chromosome segregation defects by binding to damaged DNA binding protein 1.

1 reference

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5 July 2018

COOH-terminal truncated HBV X protein plays key role in hepatocarcinogenesis

1 reference

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Interaction of hepatitis B viral oncoprotein with cellular target HBXIP dysregulates centrosome dynamics and mitotic spindle formation.

1 reference

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TP53 mutations and hepatocellular carcinoma: insights into the etiology and pathogenesis of liver cancer

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Temporal and spatial control of nucleophosmin by the Ran-Crm1 complex in centrosome duplication

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Hepatitis B virus-related insertional mutagenesis in chronic hepatitis B patients as an early drastic genetic change leading to hepatocarcinogenesis

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Hepatitis B 1762T/1764A mutations, hepatitis C infection, and codon 249 p53 mutations in hepatocellular carcinomas from Thailand

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Natural variants of hepatitis B virus X protein have differential effects on the expression of cyclin-dependent kinase inhibitor p21 gene

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Inhibition of tumorigenicity of the hepatitis B virus X gene in Chang liver cell line

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Characterisation of hepatitis B virus X protein mutants in tumour and non-tumour liver cells using laser capture microdissection.

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5 July 2018

Involvement of Crm1 in hepatitis B virus X protein-induced aberrant centriole replication and abnormal mitotic spindles

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Molecular pathogenesis of human hepatocellular carcinoma.

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5 July 2018

Hepatitis B virus X mutants derived from human hepatocellular carcinoma retain the ability to abrogate p53-induced apoptosis

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Activated ras oncogene collaborates with HBx gene of hepatitis B virus to transform cells by suppressing HBx-mediated apoptosis

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5 July 2018

Expression of integrated hepatitis B virus X variants in human hepatocellular carcinomas and its significance

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5 July 2018

Retroviral expression of the hepatitis B virus x gene promotes liver cell susceptibility to carcinogen-induced site specific mutagenesis

1 reference

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Interactions between hepatitis B virus infection and exposure to aflatoxins in the development of hepatocellular carcinoma: a molecular epidemiological approach

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5 July 2018

Hepatitis B virus X mutants, present in hepatocellular carcinoma tissue abrogate both the antiproliferative and transactivation effects of HBx.

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5 July 2018

Incidence of hepatocellular carcinoma in transgenic mice expressing the hepatitis B virus X-protein

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5 July 2018

Differential immediate early gene expression in conditional hepatitis B virus pX-transforming versus nontransforming hepatocyte cell lines

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Development of In Vitro Models for Cellular and Molecular Studies in Toxicology and Chemoprevention

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Epidemiological characteristics and risk factors of hepatocellular carcinoma

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Analysis of the tumorigenicity of the X gene of hepatitis B virus in a nontransformed hepatocyte cell line and the effects of cotransfection with a murine p53 mutant equivalent to human codon 249.

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Hepatocarcinoma-specific mutant p53-249ser induces mitotic activity but has no effect on transforming growth factor beta 1-mediated apoptosis

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HBx gene of hepatitis B virus induces liver cancer in transgenic mice

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Mutational hot spot in the p53 gene in human hepatocellular carcinomas

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10.1002/IJC.25118

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Europe PubMed Central

PubMed publication ID

31 July 2017

PMC publication ID

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Europe PubMed Central

PubMed publication ID

31 July 2017

PubMed publication ID

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Europe PubMed Central

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31 July 2017

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