Hepatitis B virus X mutants, present in hepatocellular carcinoma tissue abrogate both the antiproliferative and transactivation effects of HBx. (Q45747173)

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scientific article published in August 1999

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English	Hepatitis B virus X mutants, present in hepatocellular carcinoma tissue abrogate both the antiproliferative and transactivation effects of HBx.	scientific article published in August 1999

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

15 December 2017

http://europepmc.org/abstract/MED/10490818

Hepatitis B virus X mutants, present in hepatocellular carcinoma tissue abrogate both the antiproliferative and transactivation effects of HBx. (English)

1 reference

Europe PubMed Central

PubMed publication ID

15 December 2017

http://europepmc.org/abstract/MED/10490818

Hepatitis B virus

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based on heuristic

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hepatocellular carcinoma

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based on heuristic

inferred from title

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author name string

Sirma H

1

1 reference

Europe PubMed Central

PubMed publication ID

15 December 2017

http://europepmc.org/abstract/MED/10490818

Giannini C

2

1 reference

Europe PubMed Central

PubMed publication ID

15 December 2017

http://europepmc.org/abstract/MED/10490818

Poussin K

3

1 reference

Europe PubMed Central

PubMed publication ID

15 December 2017

http://europepmc.org/abstract/MED/10490818

Paterlini P

4

1 reference

Europe PubMed Central

PubMed publication ID

15 December 2017

http://europepmc.org/abstract/MED/10490818

Kremsdorf D

5

1 reference

Europe PubMed Central

PubMed publication ID

15 December 2017

http://europepmc.org/abstract/MED/10490818

Bréchot C

6

1 reference

Europe PubMed Central

PubMed publication ID

15 December 2017

http://europepmc.org/abstract/MED/10490818

language of work or name

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publication date

1 August 1999

1 reference

Europe PubMed Central

PubMed publication ID

15 December 2017

http://europepmc.org/abstract/MED/10490818

1 reference

Europe PubMed Central

PubMed publication ID

15 December 2017

http://europepmc.org/abstract/MED/10490818

18

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Europe PubMed Central

PubMed publication ID

15 December 2017

http://europepmc.org/abstract/MED/10490818

34

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Europe PubMed Central

PubMed publication ID

15 December 2017

http://europepmc.org/abstract/MED/10490818

4848-4859

1 reference

Europe PubMed Central

PubMed publication ID

15 December 2017

http://europepmc.org/abstract/MED/10490818

Hepatitis B virus HBx protein activates Ras-GTP complex formation and establishes a Ras, Raf, MAP kinase signaling cascade

1 reference

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Hepatitis B virus HBx protein deregulates cell cycle checkpoint controls

1 reference

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The hepatitis B virus X gene induces p53-mediated programmed cell death

1 reference

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Expression of the papillomavirus E2 protein in HeLa cells leads to apoptosis

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Hepatitis B virus X protein and p53 tumor suppressor interactions in the modulation of apoptosis

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HBx protein of hepatitis B virus interacts with the C-terminal portion of a novel human proteasome alpha-subunit

1 reference

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Hepatitis B virus transactivator HBx uses a tumour promoter signalling pathway

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21 January 2018

HBx gene of hepatitis B virus induces liver cancer in transgenic mice

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X-gene product of hepatitis B virus induces apoptosis in liver cells

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p53: puzzle and paradigm

1 reference

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Induction of cell cycle progression by hepatitis B virus HBx gene expression in quiescent mouse fibroblasts

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Establishment and characterization of cell lines constitutively expressing hepatitis B virus X-protein

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Suppression of steady-state, but not stimulus-induced NF-kappaB activity inhibits alphavirus-induced apoptosis

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HBV X protein alters the DNA binding specificity of CREB and ATF-2 by protein-protein interactions

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Analysis of the tumorigenicity of the X gene of hepatitis B virus in a nontransformed hepatocyte cell line and the effects of cotransfection with a murine p53 mutant equivalent to human codon 249.

1 reference

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21 January 2018

Effect of hepatocyte proliferation and cellular DNA synthesis on hepatitis B virus replication

1 reference

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21 January 2018

Expression of mutated hepatitis B virus X genes in human hepatocellular carcinomas

1 reference

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21 January 2018

Hepatitis B virus transactivator protein X interacts with the TATA-binding protein.

1 reference

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Review: hepatitis B virus X-gene product: a promiscuous transcriptional activator

1 reference

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The X gene of hepatitis B virus induced growth stimulation and tumorigenic transformation of mouse NIH3T3 cells

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Cytosol is the prime compartment of hepatitis B virus X protein where it colocalizes with the proteasome

1 reference

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Increased sensitivity to the hepatocarcinogen diethylnitrosamine in transgenic mice carrying the hepatitis B virus X gene

1 reference

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Hepatitis B virus HBx protein sensitizes cells to apoptotic killing by tumor necrosis factor alpha

1 reference

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Expression of hepatitis B virus X protein in HBV-infected human livers and hepatocellular carcinomas

1 reference

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The hepatitis B virus X gene potentiates c-myc-induced liver oncogenesis in transgenic mice

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p53-independent apoptotic effects of the hepatitis B virus HBx protein in vivo and in vitro

1 reference

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Genetic heterogeneity of hepatocellular carcinoma

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Isolation and molecular characterization of hepatitis B virus X-protein from a baculovirus expression system

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21 January 2018

Suppression of TNF-alpha-induced apoptosis by NF-kappaB

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Hepatitis B virus X protein inhibits p53 sequence-specific DNA binding, transcriptional activity, and association with transcription factor ERCC3

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21 January 2018

Sensitization of T cells to CD95-mediated apoptosis by HIV-1 Tat and gp120.

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21 January 2018

The hepatitis B virus X protein targets the basic region-leucine zipper domain of CREB.

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21 January 2018

Hepadnaviral X Protein:Review of Recent Progress

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21 January 2018

The woodchuck hepatitis virus X gene is important for establishment of virus infection in woodchucks.

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7 January 2021

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Human RPB5, a subunit shared by eukaryotic nuclear RNA polymerases, binds human hepatitis B virus X protein and may play a role in X transactivation

1 reference

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The hepatitis B virus HBx protein is a dual specificity cytoplasmic activator of Ras and nuclear activator of transcription factors

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Transactivation-competent bovine papillomavirus E2 protein is specifically required for efficient repression of human papillomavirus oncogene expression and for acute growth inhibition of cervical carcinoma cell lines

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Selective accumulation of the X transcript of hepatitis B virus in patients negative for hepatitis B surface antigen with hepatocellular carcinoma

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Identifiers

10.1038/SJ.ONC.1202867

1 reference

Europe PubMed Central

PubMed publication ID

15 December 2017

http://europepmc.org/abstract/MED/10490818

Dimensions Publication ID

0 references

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

15 December 2017

http://europepmc.org/abstract/MED/10490818

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