Telomerase maintains telomere structure in normal human cells. (Q52551445)

3 May 2018

title

Telomerase maintains telomere structure in normal human cells. (English)

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3 May 2018

William C Hahn

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3 May 2018

author name string

Kenkichi Masutomi

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3 May 2018

Evan Y Yu

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3 May 2018

Shilagardy Khurts

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3 May 2018

Ittai Ben-Porath

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3 May 2018

Jennifer L Currier

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3 May 2018

Geoffrey B Metz

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3 May 2018

Mary W Brooks

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3 May 2018

Shuichi Kaneko

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3 May 2018

Seishi Murakami

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3 May 2018

James A DeCaprio

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3 May 2018

Robert A Weinberg

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3 May 2018

Sheila A Stewart

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3 May 2018

language of work or name

English

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publication date

1 July 2003

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3 May 2018

published in

Cell

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3 May 2018

volume

114

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3 May 2018

issue

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3 May 2018

page(s)

241-253

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3 May 2018

Telomere shortening accompanies increased cell cycle activity during serial transplantation of hematopoietic stem cells

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7 January 2021

Constitutive telomerase expression promotes mammary carcinomas in aging mice

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Switching and signaling at the telomere

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7 January 2021

Telomere shortening and tumor formation by mouse cells lacking telomerase RNA

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7 January 2021

Extension of life-span by introduction of telomerase into normal human cells

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7 January 2021

Telomerase activity in normal and malignant hematopoietic cells

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7 January 2021

The length of telomeric G-rich strand 3'-overhang measured by oligonucleotide ligation assay

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7 January 2021

Dissociation among in vitro telomerase activity, telomere maintenance, and cellular immortalization

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7 January 2021

Telomerase activity is restored in human cells by ectopic expression of hTERT (hEST2), the catalytic subunit of telomerase

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7 January 2021

A biomarker that identifies senescent human cells in culture and in aging skin in vivo

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7 January 2021

Cell cycle-regulated generation of single-stranded G-rich DNA in the absence of telomerase

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7 January 2021

MEC3, MEC1, and DDC2 are essential components of a telomere checkpoint pathway required for cell cycle arrest during senescence in Saccharomyces cerevisiae

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7 January 2021

The nucleolar localization domain of the catalytic subunit of human telomerase

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7 January 2021

The RNA component of human telomerase

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7 January 2021

Telomerase-deficient mice with short telomeres are resistant to skin tumorigenesis.

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7 January 2021

The absence of the dna-dependent protein kinase catalytic subunit in mice results in anaphase bridges and in increased telomeric fusions with normal telomere length and G-strand overhang.

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7 January 2021

A telomeric sequence in the RNA of Tetrahymena telomerase required for telomere repeat synthesis

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7 January 2021

Mammalian telomeres end in a large duplex loop

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7 January 2021

Creation of human tumour cells with defined genetic elements

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7 January 2021

Inhibition of telomerase limits the growth of human cancer cells.

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7 January 2021

Enumeration of the simian virus 40 early region elements necessary for human cell transformation

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7 January 2021

Cooperative effect of antisense-Rb and antisense-p53 oligomers on the extension of life span in human diploid fibroblasts, TIG-1.

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7 January 2021

Telomerase activity in the regenerative basal layer of the epidermis inhuman skin and in immortal and carcinoma-derived skin keratinocytes

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7 January 2021

Telomeres shorten during ageing of human fibroblasts

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7 January 2021

Telomerase, Cell Immortality, and Cancer

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7 January 2021

Short telomeres induce a DNA damage response in Saccharomyces cerevisiae

1 reference

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7 January 2021

Generation of Telomeric G Strand Overhangs Involves Both G and C Strand Cleavage

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7 January 2021

Senescence Induced by Altered Telomere State, Not Telomere Loss

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7 January 2021

Isolation of a candidate human telomerase catalytic subunit gene, which reveals complex splicing patterns in different cell types.

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7 January 2021

Specific Association of Human Telomerase Activity with Immortal Cells and Cancer

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7 January 2021

Hypervariable ultra-long telomeres in mice

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7 January 2021

Block in anaphase chromosome separation caused by a telomerase template mutation.

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7 January 2021

Expression of TERT in early premalignant lesions and a subset of cells in normal tissues

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7 January 2021

Evidence that exposure of the telomere 3' overhang sequence induces senescence

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7 January 2021

Constitutive and regulated expression of telomerase reverse transcriptase (hTERT) in human lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900550-6

7 January 2021

Expression of mouse telomerase catalytic subunit in embryos and adult tissues.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900550-6

7 January 2021

Connecting chromosomes, crisis, and cancer

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https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900550-6

7 January 2021

Telomerase activity reconstituted in vitro with purified human telomerase reverse transcriptase and human telomerase RNA component.

1 reference

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7 January 2021

Telomerase activity and telomere length in thyroid neoplasia: biological and clinical implications

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7 January 2021

Reversing time: origin of telomerase

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7 January 2021

Telomerase Catalytic Subunit Homologs from Fission Yeast and Human

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7 January 2021

Presence of telomeric G-strand tails in the telomerase catalytic subunit TERT knockout mice

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7 January 2021

Quantitation of the frequency of immortalization of normal human diploid fibroblasts by SV40 large T-antigen

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https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900550-6

7 January 2021

Different telomere damage signaling pathways in human and mouse cells

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https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900550-6

7 January 2021

Lineage-specific telomere shortening and unaltered capacity for telomerase expression in human T and B lymphocytes with age

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900550-6

7 January 2021

Transient expression of human telomerase extends the life span of normal human fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900550-6

7 January 2021

Erosion of the telomeric single-strand overhang at replicative senescence

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7 January 2021

Lentivirus-delivered stable gene silencing by RNAi in primary cells

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7 January 2021

Est1p as a cell cycle-regulated activator of telomere-bound telomerase

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900550-6

7 January 2021

Immuno-histochemical detection of human telomerase catalytic component, hTERT, in human colorectal tumor and non-tumor tissue sections

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900550-6

7 January 2021

Analysis of genomic integrity and p53-dependent G1 checkpoint in telomerase-induced extended-life-span human fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900550-6

7 January 2021

Differentiation between senescence (M1) and crisis (M2) in human fibroblast cultures

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900550-6

7 January 2021

Subnuclear shuttling of human telomerase induced by transformation and DNA damage.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900550-6

7 January 2021

Historical claims and current interpretations of replicative aging

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900550-6

7 January 2021

Cell cycle-dependent modulation of telomerase activity in tumor cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900550-6

7 January 2021

10.1016/S0092-8674(03)00550-6

Identifiers

DOI

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3 May 2018

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3 May 2018