Salinomycin as a drug for targeting human cancer stem cells (Q21285139)

PubMed publication ID

19 August 2022

Roman Steinhart

Roman

Steinhart

1 reference

PubMed publication ID

23251084

Journal of Biomedicine and Biotechnology

19 August 2022

language of work or name

English

0 references

publication date

2012

0 references

21 November 2012

2 references

17 September 2019

12 October 2019

2 references

17 September 2019

12 October 2019

2012

0 references

page(s)

950658

0 references

Creative Commons Attribution 3.0 Unported

start time

1 January 2012

1 reference

April 2022 Public Data File from Crossref

copyrighted

1 reference

April 2022 Public Data File from Crossref

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12 September 2017

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12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516046

Phase I dose escalation trial of docetaxel plus curcumin in patients with advanced and metastatic breast cancer

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516046

Salinomycin induces apoptosis and overcomes apoptosis resistance in human cancer cells

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516046

Tumour-initiating cells: challenges and opportunities for anticancer drug discovery

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516046

Metformin selectively targets cancer stem cells, and acts together with chemotherapy to block tumor growth and prolong remission

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516046

ABCG2: the key to chemoresistance in cancer stem cells?

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516046

Acquisition of epithelial-mesenchymal transition phenotype of gemcitabine-resistant pancreatic cancer cells is linked with activation of the notch signaling pathway

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516046

Stemming resistance to HER-2 targeted therapy

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516046

ABC transporters, drug resistance, and cancer stem cells

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516046

Hedgehog signalling is essential for maintenance of cancer stem cells in myeloid leukaemia

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516046

PTEN, stem cells, and cancer stem cells

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516046

Cancer stem cell-directed therapies: recent data from the laboratory and clinic

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516046

Stem cell concepts renew cancer research

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516046

Targeting cancer stem cells with phytochemicals

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516046

Targeting cancer stem cells with monoclonal antibodies: a new perspective in cancer therapy and diagnosis

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516046

Colorectal cancer stem cells are enriched in xenogeneic tumors following chemotherapy

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516046

Crucial role of interleukin-4 in the survival of colon cancer stem cells

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516046

Identification of CD133-positive radioresistant cells in atypical teratoid/rhabdoid tumor

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516046

PI3K pathway regulates survival of cancer stem cells residing in the perivascular niche following radiation in medulloblastoma in vivo

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516046

Cancer stem cells: at the headwaters of tumor development

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516046

NF-kappaB pathway inhibitors preferentially inhibit breast cancer stem-like cells

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516046

Transformation of human mesenchymal stem cells increases their dependency on oxidative phosphorylation for energy production

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516046

WNT/beta-catenin mediates radiation resistance of mouse mammary progenitor cells

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516046

Ionophores: their use as ruminant growth promotants and impact on food safety

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516046

Antimicrobial growth promoters used in animal feed: effects of less well known antibiotics on gram-positive bacteria

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516046

Preferential induction of apoptosis for primary human leukemic stem cells

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516046

Human breast cancer cells generated by oncogenic transformation of primary mammary epithelial cells.

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516046

Salinomycin-induced polyneuropathy in cats: morphologic and epidemiologic data

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516046

Salinomycin, a new polyether antibiotic.

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516046

Salinomycin: A new monovalent cation ionophore

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516046

Inhibition of ataxia telangiectasia- and Rad3-related function abrogates the in vitro and in vivo tumorigenicity of human colon cancer cells through depletion of the CD133(+) tumor-initiating cell fraction

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516046

Salinomycin Selectively Targets ‘CD133+’ Cell Subpopulations and Decreases Malignant Traits in Colorectal Cancer Lines

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516046

Effects of Salinomycin on Cancer Stem Cell in Human Lung Adenocarcinoma A549 Cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516046

β-Catenin mediates the establishment and drug resistance of MLL leukemic stem cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516046

The anti-diabetic drug metformin suppresses self-renewal and proliferation of trastuzumab-resistant tumor-initiating breast cancer stem cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516046

The cancer stem cell selective inhibitor salinomycin is a p-glycoprotein inhibitor.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516046

High expression of large-conductance Ca2+-activated K+ channel in the CD133+ subpopulation of SH-SY5Y neuroblastoma cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516046

Wnt/beta-catenin signaling regulates cancer stem cells in lung cancer A549 cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516046

Involvement of Pin1 induction in epithelial-mesenchymal transition of tamoxifen-resistant breast cancer cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516046

Combined targeted treatment to eliminate tumorigenic cancer stem cells in human pancreatic cancer.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516046

Comparative analysis of DNA repair in stem and nonstem glioma cell cultures

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516046

HERG K+ channel expression in CD34+/CD38-/CD123(high) cells and primary leukemia cells and analysis of its regulation in leukemia cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516046

Colon cancer stem cells dictate tumor growth and resist cell death by production of interleukin-4.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516046

CD133+ HCC cancer stem cells confer chemoresistance by preferential expression of the Akt/PKB survival pathway.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516046

Wnt/beta-catenin mediates radiation resistance of Sca1+ progenitors in an immortalized mammary gland cell line

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516046

Induction of apoptosis by intracellular potassium ion depletion: using the fluorescent dye PBFI in a 96-well plate method in cultured lung cancer cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516046

Salinomycin Effects on Mitochondrial Ion Translocation and Respiration

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516046

Salinomycin in cancer: A new mission for an old agent

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516046

Curcumin and gemcitabine in patients with advanced pancreatic cancer

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516046

Comparison of Eimeria Species Distribution and Salinomycin Resistance in Commercial Broiler Operations Utilizing Different Coccidiosis Control Strategies

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516046

Persistent malignant stem cells in del(5q) myelodysplasia in remission

30 May 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F950658

Drug resistance is dramatically restored by hedgehog inhibitors in CD34+ leukemic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F950658

Cell-cycle restriction limits DNA damage and maintains self-renewal of leukaemia stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F950658

Immunoselection of breast and ovarian cancer cells with trastuzumab and natural killer cells: selective escape of CD44high/CD24low/HER2low breast cancer stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F950658

CD24+ cells from hierarchically organized ovarian cancer are enriched in cancer stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F950658

Cancer Stem Cells and Chemosensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F950658

Leukemia-initiating cells in human T-lymphoblastic leukemia exhibit glucocorticoid resistance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F950658

Targeting breast cancer stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F950658

Kitlow stem cells cause resistance to Kit/platelet-derived growth factor alpha inhibitors in murine gastrointestinal stromal tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F950658

Synergistic activity of sorafenib and sulforaphane abolishes pancreatic cancer stem cell characteristics

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F950658

Incorporating the antidiabetic drug metformin in HER2-positive breast cancer treated with neo-adjuvant chemotherapy and trastuzumab: an ongoing clinical-translational research experience at the Catalan Institute of Oncology.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F950658

Targeting cancer stem cells for more effective therapies: Taking out cancer's locomotive engine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F950658

Comparative efficacy of anticoccidials under the conditions of commercial broiler production and in battery trials.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F950658

Synthesis and antimicrobial activity of amide derivatives of polyether antibiotic-salinomycin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F950658

Acute Salinomycin Toxicosis of Pigs

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F950658

An unaddressed issue of agricultural terrorism: a case study on feed security

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F950658

Salinomycin toxicosis in horses

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F950658

The prognostic role of a gene signature from tumorigenic breast-cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F950658

Association of breast cancer stem cells identified by aldehyde dehydrogenase 1 expression with resistance to sequential Paclitaxel and epirubicin-based chemotherapy for breast cancers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F950658

Stromal niche cells protect early leukemic FLT3-ITD+ progenitor cells against first-generation FLT3 tyrosine kinase inhibitors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F950658

Multidrug Efflux Pumps and Cancer Stem Cells: Insights Into Multidrug Resistance and Therapeutic Development

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F950658

A case of human poisoning by salinomycin, an agricultural antibiotic

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516046

Persistence of malignant hematopoietic progenitors in chronic myelogenous leukemia patients in complete cytogenetic remission following imatinib mesylate treatment

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516046

Effect of salinomycin-Na on malaria parasites (Plasmodium falciparum and P. berghei)

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516046

Salinomycin poisoning in horses

29 November 2018

1 reference

12 December 2020

Apoptosis and cancer stem cells: Implications for apoptosis targeted therapy

1 reference

12 December 2020

Salinomycin can effectively kill ALDH(high) stem-like cells on gastric cancer

1 reference

12 December 2020

Comparative study of the effects of salinomycin and monensin on electrophysiologic and contractile properties of canine myocardium

1 reference

12 December 2020

A primary role for K+ and Na+ efflux in the activation of apoptosis

1 reference

12 December 2020

Anticoccidial Activity of Salinomycin in Battery Raised Broiler Chickens

1 reference

12 December 2020

Comparison of the effects of the ionophore salinomycin and adrenaline on the haemodynamics and work efficiency of the dog heart

1 reference

12 December 2020

A phase I/II study of gemcitabine-based chemotherapy plus curcumin for patients with gemcitabine-resistant pancreatic cancer

1 reference

12 December 2020

Identifiers

DOI

10.1155/2012/950658

1 reference

1 reference

1 reference

PubMed publication ID

23251084

1 reference