The cancer stem cell: premises, promises and challenges (Q37851011)

24 August 2017

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title

The cancer stem cell: premises, promises and challenges (English)

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24 August 2017

main subject

neoplastic stem cells

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Hans Clevers

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24 August 2017

language of work or name

English

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publication date

1 March 2011

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24 August 2017

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24 August 2017

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24 August 2017

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24 August 2017

page(s)

313-319

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Models, mechanisms and clinical evidence for cancer dormancy

24 August 2017

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Stem cell concepts renew cancer research

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Further evidence favoring the concept of the stem cell in ascites tumors of rats

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Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell

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A human colon cancer cell capable of initiating tumour growth in immunodeficient mice

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Isolation and molecular characterization of cancer stem cells in MMTV-Wnt-1 murine breast tumors

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Cutaneous cancer stem cell maintenance is dependent on beta-catenin signalling

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Cytokine-dependent imatinib resistance in mouse BCR-ABL+, Arf-null lymphoblastic leukemia

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Epithelial stem cells: turning over new leaves

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Glioma stem cells promote radioresistance by preferential activation of the DNA damage response

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Clinical and biological implications of CD133-positive and CD133-negative cells in glioblastomas.

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CD133 negative glioma cells form tumors in nude rats and give rise to CD133 positive cells

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A hierarchy of self-renewing tumor-initiating cell types in glioblastoma

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Biological and molecular heterogeneity of breast cancers correlates with their cancer stem cell content

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Mutational evolution in a lobular breast tumour profiled at single nucleotide resolution

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Genome remodelling in a basal-like breast cancer metastasis and xenograft

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The patterns and dynamics of genomic instability in metastatic pancreatic cancer

21 January 2018

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Distant metastasis occurs late during the genetic evolution of pancreatic cancer

21 January 2018

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A Quantitative Assay for the Number of Murine Lymphoma Cells capable of Proliferation in vivo

21 January 2018

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Microenvironmental reprogramming of thymic epithelial cells to skin multipotent stem cells

21 January 2018

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Tumors as caricatures of the process of tissue renewal: prospects for therapy by directing differentiation

21 January 2018

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12 December 2020

Tumor growth need not be driven by rare cancer stem cells

2 references

12 December 2020

7 January 2021

inferred from DOI database lookup

Acute leukemia: is there a relationship between cell growth kinetics and response to chemotherapy?

1 reference

12 December 2020

CD133 expression is not restricted to stem cells, and both CD133+ and CD133- metastatic colon cancer cells initiate tumors

1 reference

12 December 2020

MULTIPOTENTIALITY OF SINGLE EMBRYONAL CARCINOMA CELLS

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12 December 2020

Review of recent studies of cellular proliferation in acute leukemia.

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12 December 2020

Differentiation of malignant to benign cells

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12 December 2020

Improved engraftment of human acute myeloid leukemia progenitor cells in beta 2-microglobulin-deficient NOD/SCID mice and in NOD/SCID mice transgenic for human growth factors

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12 December 2020

Leukemic cell growth in SCID mice as a predictor of relapse in high-risk B-lineage acute lymphoblastic leukemia

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12 December 2020

A method for locating radioactive elements in tissues by covering histological sections with a photographic emulsion

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12 December 2020

Treatment of acute leukemia in adults

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12 December 2020

Renewal of spermatogonia in the rat

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12 December 2020

Estimation of phases of the life cycle of leukemic cells from labeling in human beings in vivo with tritiated thymidine

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12 December 2020

Studies of cellular proliferation in human leukemia. 3. Behavior of leukemic cells in three adults with acute leukemia given continuous infusions of 3H-thymidine for 8 or 10 days

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12 December 2020

Changing concepts of treatment in acute leukemia

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12 December 2020

Identification of A2B5+CD133- tumor-initiating cells in adult human gliomas

1 reference

12 December 2020

Comment on "Tumor growth need not be driven by rare cancer stem cells".

1 reference

12 December 2020

The mammary progenitor marker CD61/beta3 integrin identifies cancer stem cells in mouse models of mammary tumorigenesis

1 reference

12 December 2020

Induction of cell cycle entry eliminates human leukemia stem cells in a mouse model of AML.

1 reference

12 December 2020

Comment on "Tumor Growth Need Not Be Driven by Rare Cancer Stem Cells"

1 reference

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1038/NM.2304

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24 August 2017

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