Monoclonal antibody therapy directed against human acute myeloid leukemia stem cells (Q37809460)

23 August 2017

title

Monoclonal antibody therapy directed against human acute myeloid leukemia stem cells (English)

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23 August 2017

1 reference

1 reference

acute myeloid leukemia

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R. Majeti

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21076471

26 August 2024

language of work or name

English

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publication date

15 November 2010

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full work available at URL

23 August 2017

https://www.nature.com/articles/onc2010511.pdf

file format

Portable Document Format

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21076471

https://www.nature.com/articles/onc2010511.pdf

26 August 2024

file format

Portable Document Format

1 reference

https://api.crossref.org/works/10.1038/ONC.2010.511

https://www.nature.com/articles/onc2010511

26 August 2024

1 reference

https://api.crossref.org/works/10.1038/ONC.2010.511

26 August 2024

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23 August 2017

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23 August 2017

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23 August 2017

page(s)

1009-1019

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C-type lectin-like molecule-1: a novel myeloid cell surface marker associated with acute myeloid leukemia

23 August 2017

cites work

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Integrin-associated protein (CD47) and its ligands

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Monoclonal Antibody Therapy for B-Cell Non-Hodgkin's Lymphoma

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CD96 is a leukemic stem cell-specific marker in human acute myeloid leukemia

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CD47 is upregulated on circulating hematopoietic stem cells and leukemia cells to avoid phagocytosis

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Analysis of factors that affect in vitro chemosensitivity of leukaemic stem and progenitor cells to gemtuzumab ozogamicin (Mylotarg) in acute myeloid leukaemia.

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Targeting of CD44 eradicates human acute myeloid leukemic stem cells

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Monoclonal antibody-mediated targeting of CD123, IL-3 receptor alpha chain, eliminates human acute myeloid leukemic stem cells

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The interleukin-3 receptor alpha chain is a unique marker for human acute myelogenous leukemia stem cells

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A cell initiating human acute myeloid leukaemia after transplantation into SCID mice

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Internal tandem duplications of the FLT3 gene are present in leukemia stem cells

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Acute myeloid leukemia

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CD47 is an adverse prognostic factor and therapeutic antibody target on human acute myeloid leukemia stem cells.

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Identification of a hierarchy of multipotent hematopoietic progenitors in human cord blood

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AML1/ETO-expressing nonleukemic stem cells in acute myelogenous leukemia with 8;21 chromosomal translocation

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Negative regulation of phagocytosis in macrophages by the CD47-SHPS-1 system

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CD47-signal regulatory protein alpha (SIRPalpha) regulates Fcgamma and complement receptor-mediated phagocytosis

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Role of CD47 as a marker of self on red blood cells

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Identification of therapeutic targets for quiescent, chemotherapy-resistant human leukemia stem cells

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Human lymphoid and myeloid cell development in NOD/LtSz-scid IL2R gamma null mice engrafted with mobilized human hemopoietic stem cells

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Species- and cell type-specific interactions between CD47 and human SIRPalpha.

21 January 2018

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Polymorphism in Sirpa modulates engraftment of human hematopoietic stem cells.

21 January 2018

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The cancer stem cell hypothesis: a work in progress

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Hematopoietic stem cells express multiple myeloid markers: implications for the origin and targeted therapy of acute myeloid leukemia

21 January 2018

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Leukemia-initiating cells from some acute myeloid leukemia patients with mutated nucleophosmin reside in the CD34(-) fraction

21 January 2018

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Interleukin-2 receptor alpha-chain (CD25) expression on leukaemic blasts is predictive for outcome and level of residual disease in AML.

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Interleukin-3 receptor in acute leukemia

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High stem cell frequency in acute myeloid leukemia at diagnosis predicts high minimal residual disease and poor survival

21 January 2018

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The novel AML stem cell associated antigen CLL-1 aids in discrimination between normal and leukemic stem cells

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Expression of interleukin-3 receptor subunits on defined subpopulations of acute myeloid leukemia blasts predicts the cytotoxicity of diphtheria toxin interleukin-3 fusion protein against malignant progenitors that engraft in immunodeficient mice.

21 January 2018

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21 January 2018

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Monoclonal antibody therapy of cancer

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Ligation of the CD44 adhesion molecule reverses blockage of differentiation in human acute myeloid leukemia

31 March 2020

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31 March 2020

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The molecular basis of leukemia

31 March 2020

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31 March 2020

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Tumor growth need not be driven by rare cancer stem cells

31 March 2020

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Gemtuzumab ozogamicin in the treatment of acute myeloid leukemia

31 March 2020

1 reference

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Anti-CD38 antibody-mediated clearance of human repopulating cells masks the heterogeneity of leukemia-initiating cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.511

31 March 2020

Identifiers

DOI

10.1038/ONC.2010.511

1 reference

23 August 2017

1 reference