Serine proteases, serine protease inhibitors, and protease-activated receptors: roles in synaptic function and behavior (Q28741929)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21782155%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

review article

1 reference

title

Serine proteases, serine protease inhibitors, and protease-activated receptors: roles in synaptic function and behavior (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21782155%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21782155%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21782155%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

author name string

J David Sweatt

series ordinal

0 references

language of work or name

English

0 references

publication date

24 June 2011

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21782155%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21782155%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

volume

1407

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21782155%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

page(s)

107-122

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21782155%20AND%20SRC:MED&resulttype=core&format=json

DNA methylation and memory formation

8 February 2020

cites work

1 reference

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17 March 2017

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17 March 2017

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PAR1 and PAR2 couple to overlapping and distinct sets of G proteins and linked signaling pathways to differentially regulate cell physiology

17 March 2017

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Cellular expression pattern of the protease-activated receptor 4 in the hippocampus in naïve rats and after global ischaemia

17 March 2017

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Human neuroserpin: structure and time-dependent inhibition

17 March 2017

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17 March 2017

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The serine protease plasmin cleaves the amino-terminal domain of the NR2A subunit to relieve zinc inhibition of the N-methyl-D-aspartate receptors

17 March 2017

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Dendritic cell PAR1-S1P3 signalling couples coagulation and inflammation

17 March 2017

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17 March 2017

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17 March 2017

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Specific cleavage of agrin by neurotrypsin, a synaptic protease linked to mental retardation

17 March 2017

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The emergence of proteinase-activated receptor-2 as a novel target for the treatment of inflammation-related CNS disorders

17 March 2017

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The rewards of nicotine: regulation by tissue plasminogen activator-plasmin system through protease activated receptor-1

17 March 2017

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Protease-activated receptors in cardiovascular diseases

17 March 2017

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Neuroserpin binds Abeta and is a neuroprotective component of amyloid plaques in Alzheimer disease

17 March 2017

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Neuropsin is essential for early processes of memory acquisition and Schaffer collateral long-term potentiation in adult mouse hippocampus in vivo

17 March 2017

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Constitutive secretion of protease nexin-1 by glial cells and its regulation by G-protein-coupled receptors

17 March 2017

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Regulation of brain proteolytic activity is necessary for the in vivo function of NMDA receptors

17 March 2017

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Rapid, activity-induced increase in tissue plasminogen activator is mediated by metabotropic glutamate receptor-dependent mRNA translation

17 March 2017

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Human Mesotrypsin Is a Unique Digestive Protease Specialized for the Degradation of Trypsin Inhibitors

17 March 2017

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NMDA-dependent proteolysis of presynaptic adhesion molecule L1 in the hippocampus by neuropsin

17 March 2017

1 reference

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Acyl-enzyme complexes between tissue-type plasminogen activator and neuroserpin are short-lived in vitro

17 March 2017

1 reference

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Association between conformational mutations in neuroserpin and onset and severity of dementia

17 March 2017

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Regulation of seizure spreading by neuroserpin and tissue-type plasminogen activator is plasminogen-independent

17 March 2017

1 reference

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Crystal structure of neuroserpin: a neuronal serpin involved in a conformational disease

17 March 2017

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Abnormalities of synapses and neurons in the hippocampus of neuropsin-deficient mice

17 March 2017

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Structure of a serpin-protease complex shows inhibition by deformation

17 March 2017

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Familial dementia caused by polymerization of mutant neuroserpin

17 March 2017

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Changes in the expression of protease-activated receptor 1 and protease nexin-1 mRNA during rat nervous system development and after nerve lesion

17 March 2017

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Neuroserpin, a brain-associated inhibitor of tissue plasminogen activator is localized primarily in neurons. Implications for the regulation of motor learning and neuronal survival

17 March 2017

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Endogenous serine protease inhibitor modulates epileptic activity and hippocampal long-term potentiation

17 March 2017

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17 March 2017

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Synaptic scaling mediated by glial TNF-alpha

17 March 2017

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Thrombin signalling and protease-activated receptors

7 April 2017

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Protease-activated receptor-1 modulates hippocampal memory formation and synaptic plasticity

7 April 2017

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Neuropsin cleaves EphB2 in the amygdala to control anxiety

3 June 2018

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Neuroserpin Protects Neurons from Ischemia-Induced Plasmin-Mediated Cell Death Independently of Tissue-Type Plasminogen Activator Inhibition

3 June 2018

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Neuroserpin regulates the density of dendritic protrusions and dendritic spine shape in cultured hippocampal neurons.

3 June 2018

1 reference

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An active role for astrocytes in synaptic plasticity?

3 June 2018

1 reference

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Impaired fear extinction in mice lacking protease nexin-1.

3 June 2018

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Tissue-type plasminogen activator is a neuroprotectant in the mouse hippocampus

3 June 2018

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Do astrocytes really exocytose neurotransmitters?

3 June 2018

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Hippocampal short- and long-term plasticity are not modulated by astrocyte Ca2+ signaling

3 June 2018

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A mental retardation gene, motopsin/neurotrypsin/prss12, modulates hippocampal function and social interaction

3 June 2018

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Deficiency of PAR4 attenuates cerebral ischemia/reperfusion injury in mice

3 June 2018

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Long-term potentiation depends on release of D-serine from astrocytes

3 June 2018

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Proteinase-activated receptors in the nucleus of the solitary tract: evidence for glial-neural interactions in autonomic control of the stomach

3 June 2018

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Communication between neurons and astrocytes: relevance to the modulation of synaptic and network activity

3 June 2018

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3 June 2018

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3 June 2018

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Sorting out astrocyte physiology from pharmacology

3 June 2018

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3 June 2018

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Tissue-type plasminogen activator requires a co-receptor to enhance NMDA receptor function

3 June 2018

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Two forms of astrocyte calcium excitability have distinct effects on NMDA receptor-mediated slow inward currents in pyramidal neurons.

3 June 2018

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Rho-family GTPases modulate Ca(2+) -dependent ATP release from astrocytes.

3 June 2018

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Plasmin potentiates synaptic N-methyl-D-aspartate receptor function in hippocampal neurons through activation of protease-activated receptor-1.

3 June 2018

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Thrombin-promoted release of UDP-glucose from human astrocytoma cells.

3 June 2018

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Proteinases and signalling: pathophysiological and therapeutic implications via PARs and more.

3 June 2018

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Trypsin and trypsin-like proteases in the brain: proteolysis and cellular functions

3 June 2018

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'Role reversal' for the receptor PAR1 in sepsis-induced vascular damage

3 June 2018

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Protease-activated receptors in the brain: receptor expression, activation, and functions in neurodegeneration and neuroprotection

3 June 2018

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Tissue plasminogen activator: beyond thrombolysis

3 June 2018

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Modulation of NR2B-regulated contextual fear in the hippocampus by the tissue plasminogen activator system

3 June 2018

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Trypsin IV or mesotrypsin and p23 cleave protease-activated receptors 1 and 2 to induce inflammation and hyperalgesia

3 June 2018

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Learning and memory deficits in mice lacking protease activated receptor-1.

3 June 2018

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Protease-activated receptor signaling: new roles and regulatory mechanisms

3 June 2018

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Astrocytic control of synaptic NMDA receptors

3 June 2018

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Astrocyte control of synaptic transmission and neurovascular coupling.

3 June 2018

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Tissue-type plasminogen activator: a multifaceted modulator of neurotransmission and synaptic plasticity.

3 June 2018

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Neuroserpin: a serpin to think about

3 June 2018

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Tissue plasminogen activator and plasminogen mediate stress-induced decline of neuronal and cognitive functions in the mouse hippocampus

3 June 2018

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Activity of recombinant trypsin isoforms on human proteinase-activated receptors (PAR): mesotrypsin cannot activate epithelial PAR-1, -2, but weakly activates brain PAR-1.

3 June 2018

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Modification by the tissue plasminogen activator-plasmin system of morphine-induced dopamine release and hyperlocomotion, but not anti-nociceptive effect in mice

3 June 2018

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Glutamate receptor activation triggers a calcium-dependent and SNARE protein-dependent release of the gliotransmitter D-serine

3 June 2018

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Ethanol-withdrawal seizures are controlled by tissue plasminogen activator via modulation of NR2B-containing NMDA receptors

3 June 2018

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New functions for an old enzyme: nonhemostatic roles for tissue-type plasminogen activator in the central nervous system.

3 June 2018

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Protease-activated receptors in neuronal development, neurodegeneration, and neuroprotection: thrombin as signaling molecule in the brain

3 June 2018

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Tissue-type plasminogen activator and neuroserpin: a well-balanced act in the nervous system?

3 June 2018

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Mitogen-activated protein kinases in synaptic plasticity and memory.

3 June 2018

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Protease-activated receptor-1 in human brain: localization and functional expression in astrocytes

3 June 2018

1 reference

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Src kinases: a hub for NMDA receptor regulation

3 June 2018

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Proteinase-activated receptors in the nervous system

3 June 2018

1 reference

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Tissue-type plasminogen activator induces opening of the blood-brain barrier via the LDL receptor-related protein.

3 June 2018

1 reference

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The contribution of protease-activated receptor 1 to neuronal damage caused by transient focal cerebral ischemia

3 June 2018

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Extracellular proteases and their inhibitors in genetic diseases of the central nervous system

3 June 2018

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The role of thrombin and thrombin receptors in ischemic, hemorrhagic and traumatic brain injury: deleterious or protective?

3 June 2018

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Proteases involved in long-term potentiation

3 June 2018

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International Union of Pharmacology. XXVIII. Proteinase-activated receptors

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148282

Loss of hippocampal serine protease BSP1/neuropsin predisposes to global seizure activity.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148282

Proteinase-activated receptors.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148282

Protease activated receptors: theme and variations

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148282

Protease-activated receptors in inflammation, neuronal signaling and pain

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148282

The proteolytic activity of tissue-plasminogen activator enhances NMDA receptor-mediated signaling.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148282

The endocytic receptor protein LRP also mediates neuronal calcium signaling via N-methyl-D-aspartate receptors

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148282

Thrombin: a neuronal cell modulator

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148282

Serine proteases and brain damage - is there a link?

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148282

Role of tissue plasminogen activator receptor LRP in hippocampal long-term potentiation

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148282

Familial encephalopathy with neuroserpin inclusion bodies

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148282

A rho exchange factor mediates thrombin and Galpha(12)-induced cytoskeletal responses

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148282

Transforming growth factor-beta1 as a regulator of the serpins/t-PA axis in cerebral ischemia

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148282

Enhanced hippocampal long-term potentiation and learning by increased neuronal expression of tissue-type plasminogen activator in transgenic mice

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148282

Serine proteases in rodent hippocampus.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148282

Thrombin induced inhibition of neurite outgrowth from dorsal root ganglion neurons

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148282

Expression of Neuroserpin, an Inhibitor of Tissue Plasminogen Activator, in the Developing and Adult Nervous System of the Mouse

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148282

Protease‐Activated Receptor‐2 (PAR‐2) Is Present in the Rat Hippocampus and Is Associated with Neurodegeneration

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148282

Molecular Cloning of a Novel Brain-Specific Serine Protease with a Kringle-like Structure and Three Scavenger Receptor Cysteine-Rich Motifs1

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148282

Neurotrypsin, a novel multidomain serine protease expressed in the nervous system

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148282

Thrombin induces apoptosis in cultured neurons and astrocytes via a pathway requiring tyrosine kinase and RhoA activities.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148282

Seizures induced by intracerebral injection of thrombin: a model of intracerebral hemorrhage

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148282

Possible involvement of plasmin in long-term potentiation of rat hippocampal slices

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148282

Mice lacking the gene encoding tissue-type plasminogen activator show a selective interference with late-phase long-term potentiation in both Schaffer collateral and mossy fiber pathways

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148282

Thrombin functions as an inflammatory mediator through activation of its receptor

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148282

Tissue-plasminogen activator is induced as an immediate-early gene during seizure, kindling and long-term potentiation

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148282

Expression and activity-dependent changes of a novel limbic-serine protease gene in the hippocampus.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148282

Thrombin modulates and reverses neuroblastoma neurite outgrowth

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148282

Thrombin accumulation in brains of patients with Alzheimer's disease

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148282

Thrombin receptor activation causes rapid neural cell rounding and neurite retraction independent of classic second messengers

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148282

Cloned platelet thrombin receptor is necessary for thrombin-induced platelet activation

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148282

Channel-mediated tonic GABA release from glia.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148282

Astrocytic activation and an inhibition of MAP kinases are required for proteinase-activated receptor-2-mediated protection from neurotoxicity.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148282

Bestrophin-1 encodes for the Ca2+-activated anion channel in hippocampal astrocytes

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148282

Tissue-type plasminogen activator-plasmin-BDNF modulate glutamate-induced phase-shifts of the mouse suprachiasmatic circadian clock in vitro.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148282

A regulatory role for protease-activated receptor-2 in motivational learning in rats.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148282

Plasminogen activator activity is inhibited while neuroserpin is up-regulated in the Alzheimer disease brain

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148282

Plasmin is involved in inflammation via protease-activated receptor-1 activation in human dental pulp

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148282

Protease-activated receptor-2 regulates trypsin expression in the brain and protects against seizures and epileptogenesis.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148282

Thrombin induces long-term potentiation of reactivity to afferent stimulation and facilitates epileptic seizures in rat hippocampal slices: toward understanding the functional consequences of cerebrovascular insults.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148282

Plasma and CSF serpins in Alzheimer disease and dementia with Lewy bodies.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148282

Exacerbation of dopaminergic terminal damage in a mouse model of Parkinson's disease by the G-protein-coupled receptor protease-activated receptor 1.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148282

Regional distribution of human trypsinogen 4 in human brain at mRNA and protein level

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148282

Possible involvement of protease-activated receptor-1 in the regulation of morphine-induced dopamine release and hyperlocomotion by the tissue plasminogen activator-plasmin system

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148282

Anti-NR1 N-terminal-domain vaccination unmasks the crucial action of tPA on NMDA-receptor-mediated toxicity and spatial memory.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148282

Mesotrypsin, a brain trypsin, activates selectively proteinase-activated receptor-1, but not proteinase-activated receptor-2, in rat astrocytes.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148282

Activity-dependent release of tissue plasminogen activator from the dendritic spines of hippocampal neurons revealed by live-cell imaging

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148282

Characterization of proteinase-activated receptor 2 signalling and expression in rat hippocampal neurons and astrocytes

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148282

The brain-specific tissue-type plasminogen activator inhibitor, neuroserpin, protects neurons against excitotoxicity both in vitro and in vivo

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148282

Activation of protease-activated receptor-1 triggers astrogliosis after brain injury.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148282

Deficiency of PAR-2 gene increases acute focal ischemic brain injury

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148282

Cleavage of proBDNF by tPA/plasmin is essential for long-term hippocampal plasticity

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148282

PAR-1 deficiency protects against neuronal damage and neurologic deficits after unilateral cerebral hypoxia/ischemia

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148282

Thrombin, a mediator of neurotoxicity and memory impairment

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148282

Trypsin IV, a novel agonist of protease-activated receptors 2 and 4.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148282

Transient focal ischemia in rat brain differentially regulates mRNA expression of protease-activated receptors 1 to 4.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148282

Expression of proteinase-activated receptors in mouse microglial cells

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148282

Common signaling pathways link activation of murine PAR-1, LPA, and S1P receptors to proliferation of astrocytes.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148282

Absence of tissue plasminogen activator gene or activity impairs mouse cerebellar motor learning.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148282

Impaired explorative behavior and neophobia in genetically modified mice lacking or overexpressing the extracellular serine protease inhibitor neuroserpin

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148282

Tissue plasminogen activator and NMDA receptor cleavage

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148282

Tissue plasminogen activator in the amygdala is critical for stress-induced anxiety-like behavior

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148282

Truncating neurotrypsin mutation in autosomal recessive nonsyndromic mental retardation

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148282

Rapid, specific and active site-catalyzed effect of tissue-plasminogen activator on hippocampus-dependent learning in mice

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148282

Neuroserpin, a neuroprotective factor in focal ischemic stroke

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148282

Localization and regulation of the tissue plasminogen activator-plasmin system in the hippocampus.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148282

alpha 2-Macroglobulin exposure reduces calcium responses to N-methyl-D-aspartate via low density lipoprotein receptor-related protein in cultured hippocampal neurons

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148282

Four different types of protease-activated receptors are widely expressed in the brain and are up-regulated in hippocampus by severe ischemia.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148282

Tissue plasminogen activator controls multiple forms of synaptic plasticity and memory

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148282

Plasmin Desensitization of the PAR1 Thrombin Receptor: Kinetics, Sites of Truncation, and Implications for Thrombolytic Therapy†

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148282

Tissue plasminogen activator contributes to the late phase of LTP and to synaptic growth in the hippocampal mossy fiber pathway

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148282

Role of the thrombin receptor in development and evidence for a second receptor.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148282

A different form of long-lasting potentiation revealed in tissue plasminogen activator mutant mice.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148282

Modulatory effect of plasminogen on NMDA-induced increase in intracellular free calcium concentration in rat cultured hippocampal neurons.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148282

Cellular localization of thrombin receptor mRNA in rat brain: expression by mesencephalic dopaminergic neurons and codistribution with prothrombin mRNA.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148282

Excitotoxin-induced neuronal degeneration and seizure are mediated by tissue plasminogen activator.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148282

Focal ischemia induces expression of protease-activated receptor1 (PAR1) and PAR3 on microglia and enhances PAR4 labeling in the penumbra

27 November 2018

1 reference

12 December 2020

Prothrombin/thrombin and the thrombin receptors PAR-1 and PAR-4 in the brain: localization, expression and participation in neurodegenerative diseases

1 reference

12 December 2020

The role of thrombin-like (serine) proteases in the development, plasticity and pathology of the nervous system

1 reference

12 December 2020

Inhibitors of Na+/H+ exchange block stimulus-provoked arachidonic acid release in human platelets. Selective effects on platelet activation by epinephrine, ADP, and lower concentrations of thrombin

1 reference

12 December 2020

Thrombin causes neurite retraction in neuronal cells through activation of cell surface receptors

1 reference

12 December 2020

Variable and multiple expression of Protease Nexin-1 during mouse organogenesis and nervous system development

1 reference

12 December 2020

Hippocampal long-term potentiation and neural cell adhesion molecules L1 and NCAM

1 reference

12 December 2020

Thrombin-induced growth cone collapse: involvement of phospholipase A(2) and eicosanoid generation

1 reference

12 December 2020

Neuronal Depolarization Enhances the Transcription of the Neuronal Serine Protease Inhibitor Neuroserpin

1 reference

12 December 2020

Laminin degradation by plasmin regulates long-term potentiation

1 reference

12 December 2020

Neuropsin regulates an early phase of schaffer-collateral long-term potentiation in the murine hippocampus

1 reference

12 December 2020

Potentiation of NMDA receptor function by the serine protease thrombin

1 reference

12 December 2020

10.1016/J.BRAINRES.2011.06.042

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21782155%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21782155%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

PubMed publication ID

21782155

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21782155%20AND%20SRC:MED&resulttype=core&format=json